P63.H14INVITRO.1.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	P63.H14INVITRO.1.PS.A
Gene (human)	TP63 (GeneCards)
Gene synonyms (human)	KET, P63, P73H, P73L, TP73L
Gene (mouse)	Tp63
Gene synonyms (mouse)	P63, P73l, Tp73l, Trp63
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	9
Consensus	ndYATGKhn
GC content	43.05%
Information content (bits; total / per base)	7.388 / 0.821
Data sources	ChIP-Seq + HT-SELEX
Aligned words	7381
Previous names	P63.H12INVITRO.1.PS.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	41 (268)	0.663	0.79	0.517	0.656	0.618	0.759	1.526	2.155	98.569	281.745
Mouse	3 (16)	0.575	0.66	0.405	0.507	0.517	0.63	1.125	1.592	16.456	25.066

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.682	0.656	0.628	0.604	0.589	0.573
Non-Methyl HT-SELEX, 1 experiments	best	0.682	0.656	0.628	0.604	0.589	0.573

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.766	11.405	0.212	0.169

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	p53 domain factors {6.3} (TFClass)
TF family	p53-related {6.3.1} (TFClass)
TF subfamily	{6.3.1.0} (TFClass)
TFClass ID	TFClass: 6.3.1.0.2
HGNC	HGNC:15979
MGI	MGI:1330810
EntrezGene (human)	GeneID:8626 (SSTAR profile)
EntrezGene (mouse)	GeneID:22061 (SSTAR profile)
UniProt ID (human)	P63_HUMAN
UniProt ID (mouse)	P63_MOUSE
UniProt AC (human)	Q9H3D4 (TFClass)
UniProt AC (mouse)	O88898 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	41 human, 3 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	P63.H14INVITRO.1.PS.A.pcm
PWM	P63.H14INVITRO.1.PS.A.pwm
PFM	P63.H14INVITRO.1.PS.A.pfm
Threshold to P-value map	P63.H14INVITRO.1.PS.A.thr
Motif in other formats
JASPAR format	P63.H14INVITRO.1.PS.A_jaspar_format.txt
MEME format	P63.H14INVITRO.1.PS.A_meme_format.meme
Transfac format	P63.H14INVITRO.1.PS.A_transfac_format.txt
Homer format	P63.H14INVITRO.1.PS.A_homer_format_0.001.txt P63.H14INVITRO.1.PS.A_homer_format_0.0005.txt P63.H14INVITRO.1.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1702.0	1769.0	2286.0	1624.0
02	2822.25	706.25	2292.25	1560.25
03	501.0	5858.0	272.0	750.0
04	7381.0	0.0	0.0	0.0
05	1874.0	124.0	0.0	5383.0
06	0.0	0.0	7381.0	0.0
07	8.0	244.0	1999.0	5130.0
08	1775.25	1657.25	589.25	3359.25
09	2435.5	1989.5	1433.5	1522.5

PFM

	A	C	G	T
01	0.231	0.24	0.31	0.22
02	0.382	0.096	0.311	0.211
03	0.068	0.794	0.037	0.102
04	1.0	0.0	0.0	0.0
05	0.254	0.017	0.0	0.729
06	0.0	0.0	1.0	0.0
07	0.001	0.033	0.271	0.695
08	0.241	0.225	0.08	0.455
09	0.33	0.27	0.194	0.206

PWM

	A	C	G	T
01	-0.081	-0.042	0.214	-0.128
02	0.425	-0.958	0.217	-0.168
03	-1.301	1.154	-1.908	-0.899
04	1.385	-6.721	-6.721	-6.721
05	0.015	-2.683	-6.721	1.07
06	-6.721	-6.721	1.385	-6.721
07	-5.197	-2.015	0.08	1.022
08	-0.039	-0.107	-1.139	0.599
09	0.277	0.075	-0.252	-0.192

Standard thresholds

P-value	Threshold
0.001	5.45108
0.0005	5.991965
0.0001	6.730165