OVOL1.H14INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	OVOL1.H14INVITRO.0.SM.B
Gene (human)	OVOL1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ovol1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	ndnATAACGGThhnn
GC content	42.01%
Information content (bits; total / per base)	15.286 / 1.019
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9991
Previous names	OVOL1.H12INVITRO.0.SM.B

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	1.0	1.0	0.999	0.999	0.999
Overall, 2 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 1 experiments	median	1.0	0.999	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 1 experiments	best	1.0	0.999	1.0	0.999	0.999	0.999
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.999	0.999	0.999	0.998
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.999	0.999	0.999	0.998

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.983	0.905	0.963	0.627
batch 2	0.834	0.662	0.758	0.541

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	OVOL {2.3.3.17} (TFClass)
TFClass ID	TFClass: 2.3.3.17.1
HGNC	HGNC:8525
MGI	MGI:1330290
EntrezGene (human)	GeneID:5017 (SSTAR profile)
EntrezGene (mouse)	GeneID:18426 (SSTAR profile)
UniProt ID (human)	OVOL1_HUMAN
UniProt ID (mouse)	OVOL1_MOUSE
UniProt AC (human)	O14753 (TFClass)
UniProt AC (mouse)	Q9WTJ2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	OVOL1.H14INVITRO.0.SM.B.pcm
PWM	OVOL1.H14INVITRO.0.SM.B.pwm
PFM	OVOL1.H14INVITRO.0.SM.B.pfm
Threshold to P-value map	OVOL1.H14INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	OVOL1.H14INVITRO.0.SM.B_jaspar_format.txt
MEME format	OVOL1.H14INVITRO.0.SM.B_meme_format.meme
Transfac format	OVOL1.H14INVITRO.0.SM.B_transfac_format.txt
Homer format	OVOL1.H14INVITRO.0.SM.B_homer_format_0.001.txt OVOL1.H14INVITRO.0.SM.B_homer_format_0.0005.txt OVOL1.H14INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2096.5	2745.5	3096.5	2052.5
02	4877.0	510.0	3581.0	1023.0
03	2738.0	2053.0	3154.0	2046.0
04	7925.0	733.0	1189.0	144.0
05	13.0	17.0	14.0	9947.0
06	9953.0	18.0	14.0	6.0
07	9973.0	6.0	7.0	5.0
08	7.0	9976.0	4.0	4.0
09	12.0	11.0	9964.0	4.0
10	8.0	23.0	9942.0	18.0
11	826.0	40.0	191.0	8934.0
12	3313.0	1903.0	536.0	4239.0
13	2287.0	2963.0	480.0	4261.0
14	1935.25	2557.25	1740.25	3758.25
15	1676.0	2773.0	2724.0	2818.0

PFM

	A	C	G	T
01	0.21	0.275	0.31	0.205
02	0.488	0.051	0.358	0.102
03	0.274	0.205	0.316	0.205
04	0.793	0.073	0.119	0.014
05	0.001	0.002	0.001	0.996
06	0.996	0.002	0.001	0.001
07	0.998	0.001	0.001	0.001
08	0.001	0.998	0.0	0.0
09	0.001	0.001	0.997	0.0
10	0.001	0.002	0.995	0.002
11	0.083	0.004	0.019	0.894
12	0.332	0.19	0.054	0.424
13	0.229	0.297	0.048	0.426
14	0.194	0.256	0.174	0.376
15	0.168	0.278	0.273	0.282

PWM

	A	C	G	T
01	-0.175	0.094	0.215	-0.196
02	0.669	-1.585	0.36	-0.891
03	0.092	-0.196	0.233	-0.199
04	1.154	-1.224	-0.741	-2.838
05	-5.096	-4.864	-5.033	1.381
06	1.382	-4.813	-5.033	-5.708
07	1.384	-5.708	-5.594	-5.836
08	-5.594	1.384	-5.983	-5.983
09	-5.164	-5.236	1.383	-5.983
10	-5.492	-4.593	1.381	-4.813
11	-1.105	-4.079	-2.56	1.274
12	0.282	-0.272	-1.536	0.529
13	-0.088	0.171	-1.645	0.534
14	-0.255	0.024	-0.361	0.408
15	-0.399	0.104	0.087	0.121

Standard thresholds

P-value	Threshold
0.001	0.87276
0.0005	2.47931
0.0001	5.72151