OSR2.H14RSNP.1.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	OSR2.H14RSNP.1.M.C
Gene (human)	OSR2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Osr2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	18
Consensus	nbhGCTACTGWWKbvSYn
GC content	48.19%
Information content (bits; total / per base)	18.198 / 1.011
Data sources	Methyl-HT-SELEX
Aligned words	1058
Previous names	OSR2.H12RSNP.1.M.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.607	0.651	0.49	0.547	0.66	0.74	1.696	2.017	33.443	146.215

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.844	0.828	0.69	0.694	0.595	0.615
Overall, 2 experiments	best	0.85	0.832	0.713	0.704	0.615	0.626
Methyl HT-SELEX, 1 experiments	median	0.838	0.832	0.667	0.685	0.574	0.605
Methyl HT-SELEX, 1 experiments	best	0.838	0.832	0.667	0.685	0.574	0.605
Non-Methyl HT-SELEX, 1 experiments	median	0.85	0.824	0.713	0.704	0.615	0.626
Non-Methyl HT-SELEX, 1 experiments	best	0.85	0.824	0.713	0.704	0.615	0.626

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	5.917	1.971	0.091	0.067

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.9
HGNC	HGNC:15830
MGI	MGI:1930813
EntrezGene (human)	GeneID:116039 (SSTAR profile)
EntrezGene (mouse)	GeneID:107587 (SSTAR profile)
UniProt ID (human)	OSR2_HUMAN
UniProt ID (mouse)	OSR2_MOUSE
UniProt AC (human)	Q8N2R0 (TFClass)
UniProt AC (mouse)	Q91ZD1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	OSR2.H14RSNP.1.M.C.pcm
PWM	OSR2.H14RSNP.1.M.C.pwm
PFM	OSR2.H14RSNP.1.M.C.pfm
Threshold to P-value map	OSR2.H14RSNP.1.M.C.thr
Motif in other formats
JASPAR format	OSR2.H14RSNP.1.M.C_jaspar_format.txt
MEME format	OSR2.H14RSNP.1.M.C_meme_format.meme
Transfac format	OSR2.H14RSNP.1.M.C_transfac_format.txt
Homer format	OSR2.H14RSNP.1.M.C_homer_format_0.001.txt OSR2.H14RSNP.1.M.C_homer_format_0.0005.txt OSR2.H14RSNP.1.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	334.75	195.75	286.75	240.75
02	137.0	147.0	371.0	403.0
03	190.0	150.0	93.0	625.0
04	0.0	2.0	1056.0	0.0
05	0.0	1058.0	0.0	0.0
06	0.0	0.0	0.0	1058.0
07	1058.0	0.0	0.0	0.0
08	0.0	1058.0	0.0	0.0
09	0.0	3.0	0.0	1055.0
10	0.0	0.0	1022.0	36.0
11	525.0	19.0	19.0	495.0
12	554.0	1.0	219.0	284.0
13	31.0	126.0	562.0	339.0
14	102.0	136.0	225.0	595.0
15	623.0	158.0	191.0	86.0
16	86.0	167.0	697.0	108.0
17	98.5	761.5	69.5	128.5
18	416.0	199.0	184.0	259.0

PFM

	A	C	G	T
01	0.316	0.185	0.271	0.228
02	0.129	0.139	0.351	0.381
03	0.18	0.142	0.088	0.591
04	0.0	0.002	0.998	0.0
05	0.0	1.0	0.0	0.0
06	0.0	0.0	0.0	1.0
07	1.0	0.0	0.0	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.003	0.0	0.997
10	0.0	0.0	0.966	0.034
11	0.496	0.018	0.018	0.468
12	0.524	0.001	0.207	0.268
13	0.029	0.119	0.531	0.32
14	0.096	0.129	0.213	0.562
15	0.589	0.149	0.181	0.081
16	0.081	0.158	0.659	0.102
17	0.093	0.72	0.066	0.121
18	0.393	0.188	0.174	0.245

PWM

	A	C	G	T
01	0.234	-0.299	0.08	-0.093
02	-0.652	-0.582	0.336	0.419
03	-0.328	-0.562	-1.033	0.856
04	-5.03	-4.265	1.379	-5.03
05	-5.03	1.381	-5.03	-5.03
06	-5.03	-5.03	-5.03	1.381
07	1.381	-5.03	-5.03	-5.03
08	-5.03	1.381	-5.03	-5.03
09	-5.03	-4.028	-5.03	1.379
10	-5.03	-5.03	1.347	-1.954
11	0.682	-2.552	-2.552	0.624
12	0.736	-4.576	-0.187	0.071
13	-2.096	-0.734	0.75	0.247
14	-0.943	-0.659	-0.161	0.807
15	0.853	-0.511	-0.323	-1.11
16	-1.11	-0.456	0.965	-0.886
17	-0.977	1.053	-1.318	-0.715
18	0.45	-0.282	-0.36	-0.021

Standard thresholds

P-value	Threshold
0.001	-0.51324
0.0005	1.23861
0.0001	4.69886