MotifONEC2.H14RSNP.3.P.D
Gene (human)ONECUT2
(GeneCards)
Gene synonyms (human)HNF6B
Gene (mouse)Onecut2
Gene synonyms (mouse)Oc2
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
D
Motif length22
ConsensusATKKWTTKATTGATTKWTTKWT
GC content22.34%
Information content (bits; total / per base)28.307 / 1.287
Data sourcesChIP-Seq
Aligned words257
Previous namesONEC2.H12RSNP.3.P.D

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (22) 0.762 0.89 0.676 0.846 0.684 0.769 2.388 2.9 20.194 62.921
Mouse 2 (12) 0.962 0.978 0.934 0.959 0.742 0.793 5.064 6.505 245.37 325.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.967 0.95 0.885 0.867 0.783 0.765
best 0.994 0.991 0.99 0.984 0.981 0.972
Methyl HT-SELEX, 3 experiments median 0.993 0.988 0.99 0.983 0.967 0.958
best 0.994 0.991 0.99 0.984 0.981 0.972
Non-Methyl HT-SELEX, 5 experiments median 0.905 0.858 0.839 0.794 0.729 0.711
best 0.983 0.969 0.977 0.96 0.963 0.943
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.2
HGNCHGNC:8139
MGIMGI:1891408
EntrezGene (human)GeneID:9480
(SSTAR profile)
EntrezGene (mouse)GeneID:225631
(SSTAR profile)
UniProt ID (human)ONEC2_HUMAN
UniProt ID (mouse)ONEC2_MOUSE
UniProt AC (human)O95948
(TFClass)
UniProt AC (mouse)Q6XBJ3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01203.07.07.040.0
0222.011.09.0215.0
0319.012.020.0206.0
0421.014.0191.031.0
05191.024.010.032.0
0613.015.07.0222.0
077.08.013.0229.0
084.010.0127.0116.0
09257.00.00.00.0
100.00.00.0257.0
110.01.00.0256.0
120.00.0257.00.0
13257.00.00.00.0
140.00.00.0257.0
150.04.00.0253.0
1611.07.0154.085.0
17179.013.020.045.0
186.020.04.0227.0
196.07.013.0231.0
2012.016.0185.044.0
21176.023.017.041.0
2213.022.015.0207.0
PFM
ACGT
010.790.0270.0270.156
020.0860.0430.0350.837
030.0740.0470.0780.802
040.0820.0540.7430.121
050.7430.0930.0390.125
060.0510.0580.0270.864
070.0270.0310.0510.891
080.0160.0390.4940.451
091.00.00.00.0
100.00.00.01.0
110.00.0040.00.996
120.00.01.00.0
131.00.00.00.0
140.00.00.01.0
150.00.0160.00.984
160.0430.0270.5990.331
170.6960.0510.0780.175
180.0230.0780.0160.883
190.0230.0270.0510.899
200.0470.0620.720.171
210.6850.0890.0660.16
220.0510.0860.0580.805
PWM
ACGT
011.136-2.057-2.057-0.461
02-1.032-1.667-1.8441.193
03-1.169-1.59-1.1211.15
04-1.076-1.4511.075-0.706
051.075-0.95-1.752-0.676
06-1.518-1.388-2.0571.225
07-2.057-1.945-1.5181.256
08-2.5-1.7520.6710.581
091.37-3.857-3.857-3.857
10-3.857-3.857-3.8571.37
11-3.857-3.314-3.8571.366
12-3.857-3.8571.37-3.857
131.37-3.857-3.857-3.857
14-3.857-3.857-3.8571.37
15-3.857-2.5-3.8571.355
16-1.667-2.0570.8620.275
171.011-1.518-1.121-0.347
18-2.184-1.121-2.51.247
19-2.184-2.057-1.5181.264
20-1.59-1.3281.044-0.369
210.994-0.99-1.272-0.437
22-1.518-1.032-1.3881.155
Standard thresholds
P-value Threshold
0.001 -3.64719
0.0005 -1.99139
0.0001 1.55491