| Motif | ONEC2.H14INVIVO.3.P.B |
| Gene (human) | ONECUT2 (GeneCards) |
| Gene synonyms (human) | HNF6B |
| Gene (mouse) | Onecut2 |
| Gene synonyms (mouse) | Oc2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 3 |
| Quality | B |
| Motif | ONEC2.H14INVIVO.3.P.B |
| Gene (human) | ONECUT2 (GeneCards) |
| Gene synonyms (human) | HNF6B |
| Gene (mouse) | Onecut2 |
| Gene synonyms (mouse) | Oc2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 3 |
| Quality | B |
| Motif length | 22 |
| Consensus | KKATTGATTKWTTKWhTKRKWK |
| GC content | 25.97% |
| Information content (bits; total / per base) | 25.543 / 1.161 |
| Data sources | ChIP-Seq |
| Aligned words | 324 |
| Previous names | ONEC2.H12INVIVO.3.P.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 4 (22) | 0.741 | 0.882 | 0.603 | 0.772 | 0.72 | 0.797 | 2.523 | 3.094 | 24.561 | 95.959 |
| Mouse | 2 (12) | 0.893 | 0.924 | 0.844 | 0.889 | 0.787 | 0.835 | 5.381 | 6.746 | 279.353 | 350.854 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.962 | 0.945 | 0.87 | 0.856 | 0.79 | 0.764 |
| best | 0.994 | 0.989 | 0.99 | 0.984 | 0.976 | 0.967 | |
| Methyl HT-SELEX, 3 experiments | median | 0.994 | 0.989 | 0.984 | 0.977 | 0.91 | 0.904 |
| best | 0.994 | 0.989 | 0.99 | 0.984 | 0.976 | 0.967 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.86 | 0.811 | 0.787 | 0.741 | 0.704 | 0.677 |
| best | 0.97 | 0.952 | 0.947 | 0.921 | 0.918 | 0.885 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-CUT {3.1.9} (TFClass) |
| TF subfamily | ONECUT {3.1.9.1} (TFClass) |
| TFClass ID | TFClass: 3.1.9.1.2 |
| HGNC | HGNC:8139 |
| MGI | MGI:1891408 |
| EntrezGene (human) | GeneID:9480 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:225631 (SSTAR profile) |
| UniProt ID (human) | ONEC2_HUMAN |
| UniProt ID (mouse) | ONEC2_MOUSE |
| UniProt AC (human) | O95948 (TFClass) |
| UniProt AC (mouse) | Q6XBJ3 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 4 human, 2 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 3 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | ONEC2.H14INVIVO.3.P.B.pcm |
| PWM | ONEC2.H14INVIVO.3.P.B.pwm |
| PFM | ONEC2.H14INVIVO.3.P.B.pfm |
| Threshold to P-value map | ONEC2.H14INVIVO.3.P.B.thr |
| Motif in other formats | |
| JASPAR format | ONEC2.H14INVIVO.3.P.B_jaspar_format.txt |
| MEME format | ONEC2.H14INVIVO.3.P.B_meme_format.meme |
| Transfac format | ONEC2.H14INVIVO.3.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 29.0 | 33.0 | 40.0 | 222.0 |
| 02 | 3.0 | 18.0 | 103.0 | 200.0 |
| 03 | 324.0 | 0.0 | 0.0 | 0.0 |
| 04 | 0.0 | 0.0 | 0.0 | 324.0 |
| 05 | 1.0 | 0.0 | 0.0 | 323.0 |
| 06 | 0.0 | 0.0 | 323.0 | 1.0 |
| 07 | 324.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 3.0 | 0.0 | 321.0 |
| 09 | 0.0 | 12.0 | 0.0 | 312.0 |
| 10 | 23.0 | 13.0 | 170.0 | 118.0 |
| 11 | 217.0 | 23.0 | 27.0 | 57.0 |
| 12 | 15.0 | 19.0 | 8.0 | 282.0 |
| 13 | 12.0 | 16.0 | 9.0 | 287.0 |
| 14 | 15.0 | 17.0 | 234.0 | 58.0 |
| 15 | 242.0 | 20.0 | 27.0 | 35.0 |
| 16 | 23.0 | 23.0 | 20.0 | 258.0 |
| 17 | 13.0 | 12.0 | 25.0 | 274.0 |
| 18 | 29.0 | 17.0 | 219.0 | 59.0 |
| 19 | 221.0 | 29.0 | 42.0 | 32.0 |
| 20 | 23.0 | 29.0 | 35.0 | 237.0 |
| 21 | 34.0 | 29.0 | 23.0 | 238.0 |
| 22 | 33.0 | 32.0 | 201.0 | 58.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.09 | 0.102 | 0.123 | 0.685 |
| 02 | 0.009 | 0.056 | 0.318 | 0.617 |
| 03 | 1.0 | 0.0 | 0.0 | 0.0 |
| 04 | 0.0 | 0.0 | 0.0 | 1.0 |
| 05 | 0.003 | 0.0 | 0.0 | 0.997 |
| 06 | 0.0 | 0.0 | 0.997 | 0.003 |
| 07 | 1.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.009 | 0.0 | 0.991 |
| 09 | 0.0 | 0.037 | 0.0 | 0.963 |
| 10 | 0.071 | 0.04 | 0.525 | 0.364 |
| 11 | 0.67 | 0.071 | 0.083 | 0.176 |
| 12 | 0.046 | 0.059 | 0.025 | 0.87 |
| 13 | 0.037 | 0.049 | 0.028 | 0.886 |
| 14 | 0.046 | 0.052 | 0.722 | 0.179 |
| 15 | 0.747 | 0.062 | 0.083 | 0.108 |
| 16 | 0.071 | 0.071 | 0.062 | 0.796 |
| 17 | 0.04 | 0.037 | 0.077 | 0.846 |
| 18 | 0.09 | 0.052 | 0.676 | 0.182 |
| 19 | 0.682 | 0.09 | 0.13 | 0.099 |
| 20 | 0.071 | 0.09 | 0.108 | 0.731 |
| 21 | 0.105 | 0.09 | 0.071 | 0.735 |
| 22 | 0.102 | 0.099 | 0.62 | 0.179 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.996 | -0.873 | -0.688 | 0.997 |
| 02 | -2.92 | -1.445 | 0.237 | 0.893 |
| 03 | 1.373 | -4.044 | -4.044 | -4.044 |
| 04 | -4.044 | -4.044 | -4.044 | 1.373 |
| 05 | -3.518 | -4.044 | -4.044 | 1.37 |
| 06 | -4.044 | -4.044 | 1.37 | -3.518 |
| 07 | 1.373 | -4.044 | -4.044 | -4.044 |
| 08 | -4.044 | -2.92 | -4.044 | 1.364 |
| 09 | -4.044 | -1.814 | -4.044 | 1.335 |
| 10 | -1.216 | -1.742 | 0.732 | 0.371 |
| 11 | 0.974 | -1.216 | -1.064 | -0.344 |
| 12 | -1.612 | -1.394 | -2.167 | 1.235 |
| 13 | -1.814 | -1.553 | -2.066 | 1.252 |
| 14 | -1.612 | -1.497 | 1.049 | -0.327 |
| 15 | 1.083 | -1.347 | -1.064 | -0.816 |
| 16 | -1.216 | -1.216 | -1.347 | 1.146 |
| 17 | -1.742 | -1.814 | -1.137 | 1.206 |
| 18 | -0.996 | -1.497 | 0.984 | -0.31 |
| 19 | 0.993 | -0.996 | -0.641 | -0.902 |
| 20 | -1.216 | -0.996 | -0.816 | 1.062 |
| 21 | -0.844 | -0.996 | -1.216 | 1.066 |
| 22 | -0.873 | -0.902 | 0.898 | -0.327 |
| P-value | Threshold |
|---|---|
| 0.001 | -2.25924 |
| 0.0005 | -0.66299 |
| 0.0001 | 2.73986 |