MotifOLIG2.H14CORE.0.P.B
Gene (human)OLIG2
(GeneCards)
Gene synonyms (human)BHLHB1, BHLHE19, PRKCBP2, RACK17
Gene (mouse)Olig2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length19
ConsensusMCAKCTGbYbnShdbvhbb
GC content56.75%
Information content (bits; total / per base)12.034 / 0.633
Data sourcesChIP-Seq
Aligned words999
Previous namesOLIG2.H12CORE.0.P.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (40) 0.739 0.805 0.614 0.687 0.665 0.721 1.917 2.158 43.112 110.523
Mouse 9 (60) 0.86 0.911 0.747 0.826 0.776 0.866 2.366 3.143 145.507 269.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.807 0.748 0.723 0.682 0.645 0.627
best 0.969 0.948 0.936 0.91 0.842 0.824
Methyl HT-SELEX, 2 experiments median 0.952 0.924 0.913 0.879 0.828 0.802
best 0.969 0.948 0.936 0.91 0.842 0.824
Non-Methyl HT-SELEX, 6 experiments median 0.733 0.682 0.653 0.625 0.591 0.582
best 0.947 0.917 0.902 0.867 0.818 0.79

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.022 1.785 0.426 0.18

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.868 0.309 0.803 0.532
batch 2 0.628 0.371 0.624 0.44
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyNeurogenin-ATO {1.2.3.4} (TFClass)
TFClass IDTFClass: 1.2.3.4.14
HGNCHGNC:9398
MGIMGI:1355331
EntrezGene (human)GeneID:10215
(SSTAR profile)
EntrezGene (mouse)GeneID:50913
(SSTAR profile)
UniProt ID (human)OLIG2_HUMAN
UniProt ID (mouse)OLIG2_MOUSE
UniProt AC (human)Q13516
(TFClass)
UniProt AC (mouse)Q9EQW6
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 9 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01247.0555.0176.021.0
02120.0875.02.02.0
03905.05.018.071.0
047.015.0646.0331.0
05182.0799.013.05.0
0630.08.05.0956.0
070.02.0954.043.0
088.0365.0277.0349.0
0975.0182.0101.0641.0
10125.0234.0246.0394.0
11186.0282.0258.0273.0
1267.0668.0148.0116.0
13274.0473.080.0172.0
14439.079.0298.0183.0
1586.0210.0497.0206.0
16211.0494.0190.0104.0
17186.0234.0103.0476.0
1893.0148.0513.0245.0
1997.0277.0341.0284.0
PFM
ACGT
010.2470.5560.1760.021
020.120.8760.0020.002
030.9060.0050.0180.071
040.0070.0150.6470.331
050.1820.80.0130.005
060.030.0080.0050.957
070.00.0020.9550.043
080.0080.3650.2770.349
090.0750.1820.1010.642
100.1250.2340.2460.394
110.1860.2820.2580.273
120.0670.6690.1480.116
130.2740.4730.080.172
140.4390.0790.2980.183
150.0860.210.4970.206
160.2110.4940.190.104
170.1860.2340.1030.476
180.0930.1480.5140.245
190.0970.2770.3410.284
PWM
ACGT
01-0.0110.795-0.347-2.404
02-0.7261.249-4.212-4.212
031.282-3.621-2.545-1.241
04-3.361-2.710.9460.28
05-0.3141.158-2.838-3.621
06-2.07-3.252-3.6211.337
07-4.981-4.2121.335-1.727
08-3.2520.3770.1030.333
09-1.187-0.314-0.8950.938
10-0.685-0.065-0.0150.453
11-0.2920.1210.0320.088
12-1.2970.98-0.519-0.759
130.0920.635-1.124-0.37
140.561-1.1360.176-0.308
15-1.053-0.1720.685-0.191
16-0.1670.679-0.271-0.866
17-0.292-0.065-0.8760.642
18-0.976-0.5190.716-0.019
19-0.9350.1030.310.128
Standard thresholds
P-value Threshold
0.001 4.19751
0.0005 5.19281
0.0001 7.20856