NR2F6.H14INVIVO.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NR2F6.H14INVIVO.0.P.C
Gene (human)	NR2F6 (GeneCards)
Gene synonyms (human)	EAR2, ERBAL2
Gene (mouse)	Nr2f6
Gene synonyms (mouse)	Ear-2, Ear2, Erbal2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	17
Consensus	ddbvbvWRAGGTCAvvv
GC content	53.16%
Information content (bits; total / per base)	12.452 / 0.732
Data sources	ChIP-Seq
Aligned words	1002
Previous names	NR2F6.H12INVIVO.0.P.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.883	0.901	0.788	0.81	0.886	0.907	3.543	3.689	223.42	270.155

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 11 experiments	median	0.925	0.896	0.84	0.809	0.727	0.717
Overall, 11 experiments	best	0.999	0.999	0.991	0.988	0.976	0.966
Methyl HT-SELEX, 3 experiments	median	0.991	0.986	0.983	0.974	0.959	0.948
Methyl HT-SELEX, 3 experiments	best	0.997	0.995	0.987	0.982	0.968	0.954
Non-Methyl HT-SELEX, 8 experiments	median	0.79	0.79	0.656	0.668	0.578	0.599
Non-Methyl HT-SELEX, 8 experiments	best	0.999	0.999	0.991	0.988	0.976	0.966

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	RXR-related receptors {2.1.3} (TFClass)
TF subfamily	COUP (NR2F) {2.1.3.5} (TFClass)
TFClass ID	TFClass: 2.1.3.5.3
HGNC	HGNC:7977
MGI	MGI:1352453
EntrezGene (human)	GeneID:2063 (SSTAR profile)
EntrezGene (mouse)	GeneID:13864 (SSTAR profile)
UniProt ID (human)	NR2F6_HUMAN
UniProt ID (mouse)	NR2F6_MOUSE
UniProt AC (human)	P10588 (TFClass)
UniProt AC (mouse)	P43136 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	8
Methyl-HT-SELEX	3
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	NR2F6.H14INVIVO.0.P.C.pcm
PWM	NR2F6.H14INVIVO.0.P.C.pwm
PFM	NR2F6.H14INVIVO.0.P.C.pfm
Threshold to P-value map	NR2F6.H14INVIVO.0.P.C.thr
Motif in other formats
JASPAR format	NR2F6.H14INVIVO.0.P.C_jaspar_format.txt
MEME format	NR2F6.H14INVIVO.0.P.C_meme_format.meme
Transfac format	NR2F6.H14INVIVO.0.P.C_transfac_format.txt
Homer format	NR2F6.H14INVIVO.0.P.C_homer_format_0.001.txt NR2F6.H14INVIVO.0.P.C_homer_format_0.0005.txt NR2F6.H14INVIVO.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	275.0	156.0	396.0	175.0
02	410.0	90.0	336.0	166.0
03	145.0	163.0	535.0	159.0
04	175.0	211.0	475.0	141.0
05	142.0	278.0	192.0	390.0
06	151.0	568.0	153.0	130.0
07	708.0	78.0	92.0	124.0
08	440.0	44.0	485.0	33.0
09	833.0	0.0	165.0	4.0
10	14.0	0.0	987.0	1.0
11	11.0	5.0	970.0	16.0
12	1.0	42.0	54.0	905.0
13	5.0	917.0	39.0	41.0
14	973.0	7.0	17.0	5.0
15	353.0	207.0	334.0	108.0
16	371.0	156.0	350.0	125.0
17	286.0	173.0	380.0	163.0

PFM

	A	C	G	T
01	0.274	0.156	0.395	0.175
02	0.409	0.09	0.335	0.166
03	0.145	0.163	0.534	0.159
04	0.175	0.211	0.474	0.141
05	0.142	0.277	0.192	0.389
06	0.151	0.567	0.153	0.13
07	0.707	0.078	0.092	0.124
08	0.439	0.044	0.484	0.033
09	0.831	0.0	0.165	0.004
10	0.014	0.0	0.985	0.001
11	0.011	0.005	0.968	0.016
12	0.001	0.042	0.054	0.903
13	0.005	0.915	0.039	0.041
14	0.971	0.007	0.017	0.005
15	0.352	0.207	0.333	0.108
16	0.37	0.156	0.349	0.125
17	0.285	0.173	0.379	0.163

PWM

	A	C	G	T
01	0.093	-0.469	0.455	-0.356
02	0.49	-1.012	0.292	-0.408
03	-0.542	-0.426	0.755	-0.451
04	-0.356	-0.17	0.637	-0.569
05	-0.562	0.103	-0.264	0.44
06	-0.502	0.815	-0.489	-0.65
07	1.035	-1.152	-0.99	-0.696
08	0.56	-1.708	0.657	-1.983
09	1.197	-4.984	-0.414	-3.785
10	-2.775	-4.984	1.366	-4.527
11	-2.987	-3.624	1.349	-2.655
12	-4.527	-1.752	-1.51	1.28
13	-3.624	1.293	-1.823	-1.775
14	1.352	-3.364	-2.6	-3.624
15	0.341	-0.189	0.286	-0.832
16	0.391	-0.469	0.333	-0.688
17	0.132	-0.367	0.414	-0.426

Standard thresholds

P-value	Threshold
0.001	3.98151
0.0005	5.03016
0.0001	7.18346