NR2F6.H14INVITRO.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NR2F6.H14INVITRO.1.PSM.A
Gene (human)	NR2F6 (GeneCards)
Gene synonyms (human)	EAR2, ERBAL2
Gene (mouse)	Nr2f6
Gene synonyms (mouse)	Ear-2, Ear2, Erbal2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	11
Consensus	ndRGGTSRddn
GC content	50.58%
Information content (bits; total / per base)	7.035 / 0.64
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	8385
Previous names	NR2F6.H12INVITRO.1.PSM.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.869	0.888	0.767	0.793	0.853	0.868	2.83	2.993	219.62	265.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 11 experiments	median	0.955	0.932	0.897	0.868	0.79	0.774
Overall, 11 experiments	best	0.999	0.998	0.995	0.993	0.985	0.979
Methyl HT-SELEX, 3 experiments	median	0.99	0.983	0.985	0.975	0.974	0.961
Methyl HT-SELEX, 3 experiments	best	0.997	0.996	0.994	0.991	0.985	0.979
Non-Methyl HT-SELEX, 8 experiments	median	0.815	0.811	0.68	0.687	0.6	0.615
Non-Methyl HT-SELEX, 8 experiments	best	0.999	0.998	0.995	0.993	0.981	0.972

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	RXR-related receptors {2.1.3} (TFClass)
TF subfamily	COUP (NR2F) {2.1.3.5} (TFClass)
TFClass ID	TFClass: 2.1.3.5.3
HGNC	HGNC:7977
MGI	MGI:1352453
EntrezGene (human)	GeneID:2063 (SSTAR profile)
EntrezGene (mouse)	GeneID:13864 (SSTAR profile)
UniProt ID (human)	NR2F6_HUMAN
UniProt ID (mouse)	NR2F6_MOUSE
UniProt AC (human)	P10588 (TFClass)
UniProt AC (mouse)	P43136 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	8
Methyl-HT-SELEX	3
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	NR2F6.H14INVITRO.1.PSM.A.pcm
PWM	NR2F6.H14INVITRO.1.PSM.A.pwm
PFM	NR2F6.H14INVITRO.1.PSM.A.pfm
Threshold to P-value map	NR2F6.H14INVITRO.1.PSM.A.thr
Motif in other formats
JASPAR format	NR2F6.H14INVITRO.1.PSM.A_jaspar_format.txt
MEME format	NR2F6.H14INVITRO.1.PSM.A_meme_format.meme
Transfac format	NR2F6.H14INVITRO.1.PSM.A_transfac_format.txt
Homer format	NR2F6.H14INVITRO.1.PSM.A_homer_format_0.001.txt NR2F6.H14INVITRO.1.PSM.A_homer_format_0.0005.txt NR2F6.H14INVITRO.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3360.5	1488.5	1787.5	1748.5
02	3538.5	695.5	3020.5	1130.5
03	5254.0	542.0	2004.0	585.0
04	13.0	84.0	7963.0	325.0
05	99.0	82.0	7735.0	469.0
06	6.0	127.0	647.0	7605.0
07	426.0	5629.0	1665.0	665.0
08	5216.0	350.0	2091.0	728.0
09	2420.0	1159.0	1746.0	3060.0
10	2703.75	970.75	2581.75	2128.75
11	1952.0	1236.0	3051.0	2146.0

PFM

	A	C	G	T
01	0.401	0.178	0.213	0.209
02	0.422	0.083	0.36	0.135
03	0.627	0.065	0.239	0.07
04	0.002	0.01	0.95	0.039
05	0.012	0.01	0.922	0.056
06	0.001	0.015	0.077	0.907
07	0.051	0.671	0.199	0.079
08	0.622	0.042	0.249	0.087
09	0.289	0.138	0.208	0.365
10	0.322	0.116	0.308	0.254
11	0.233	0.147	0.364	0.256

PWM

	A	C	G	T
01	0.472	-0.342	-0.159	-0.181
02	0.523	-1.101	0.365	-0.617
03	0.918	-1.35	-0.045	-1.274
04	-4.924	-3.192	1.334	-1.858
05	-3.031	-3.215	1.305	-1.494
06	-5.538	-2.787	-1.173	1.288
07	-1.589	0.987	-0.23	-1.146
08	0.911	-1.785	-0.003	-1.056
09	0.143	-0.592	-0.183	0.378
10	0.254	-0.769	0.208	0.015
11	-0.071	-0.528	0.375	0.023

Standard thresholds

P-value	Threshold
0.001	5.16919
0.0005	5.76516
0.0001	6.91626