NFE2.H14INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFE2.H14INVIVO.0.P.B
Gene (human)	NFE2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Nfe2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	RTGACTCAGCAndhh
GC content	44.73%
Information content (bits; total / per base)	17.508 / 1.167
Data sources	ChIP-Seq
Aligned words	994
Previous names	NFE2.H12INVIVO.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (34)	0.892	0.983	0.88	0.977	0.888	0.984	6.054	7.869	668.966	1098.42
Mouse	4 (26)	0.961	0.994	0.952	0.989	0.965	0.997	7.545	8.414	424.824	749.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.754	0.75	0.74	0.738	0.729	0.724
Overall, 4 experiments	best	0.986	0.976	0.98	0.966	0.965	0.947
Methyl HT-SELEX, 1 experiments	median	0.986	0.976	0.979	0.966	0.962	0.944
Methyl HT-SELEX, 1 experiments	best	0.986	0.976	0.979	0.966	0.962	0.944
Non-Methyl HT-SELEX, 3 experiments	median	0.522	0.525	0.502	0.51	0.496	0.503
Non-Methyl HT-SELEX, 3 experiments	best	0.986	0.974	0.98	0.966	0.965	0.947

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	5.292	3.927	0.247	0.211

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.617	0.306	0.545	0.387
batch 2	0.735	0.307	0.607	0.345

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.1
HGNC	HGNC:7780
MGI	MGI:97308
EntrezGene (human)	GeneID:4778 (SSTAR profile)
EntrezGene (mouse)	GeneID:18022 (SSTAR profile)
UniProt ID (human)	NFE2_HUMAN
UniProt ID (mouse)	NFE2_MOUSE
UniProt AC (human)	Q16621 (TFClass)
UniProt AC (mouse)	Q07279 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	3
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	NFE2.H14INVIVO.0.P.B.pcm
PWM	NFE2.H14INVIVO.0.P.B.pwm
PFM	NFE2.H14INVIVO.0.P.B.pfm
Threshold to P-value map	NFE2.H14INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	NFE2.H14INVIVO.0.P.B_jaspar_format.txt
MEME format	NFE2.H14INVIVO.0.P.B_meme_format.meme
Transfac format	NFE2.H14INVIVO.0.P.B_transfac_format.txt
Homer format	NFE2.H14INVIVO.0.P.B_homer_format_0.001.txt NFE2.H14INVIVO.0.P.B_homer_format_0.0005.txt NFE2.H14INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	682.0	32.0	279.0	1.0
02	0.0	1.0	2.0	991.0
03	0.0	2.0	984.0	8.0
04	984.0	2.0	6.0	2.0
05	15.0	825.0	126.0	28.0
06	61.0	9.0	34.0	890.0
07	52.0	872.0	35.0	35.0
08	867.0	12.0	71.0	44.0
09	8.0	0.0	971.0	15.0
10	5.0	969.0	16.0	4.0
11	866.0	11.0	71.0	46.0
12	261.0	163.0	407.0	163.0
13	286.0	101.0	165.0	442.0
14	295.0	112.0	71.0	516.0
15	355.0	211.0	109.0	319.0

PFM

	A	C	G	T
01	0.686	0.032	0.281	0.001
02	0.0	0.001	0.002	0.997
03	0.0	0.002	0.99	0.008
04	0.99	0.002	0.006	0.002
05	0.015	0.83	0.127	0.028
06	0.061	0.009	0.034	0.895
07	0.052	0.877	0.035	0.035
08	0.872	0.012	0.071	0.044
09	0.008	0.0	0.977	0.015
10	0.005	0.975	0.016	0.004
11	0.871	0.011	0.071	0.046
12	0.263	0.164	0.409	0.164
13	0.288	0.102	0.166	0.445
14	0.297	0.113	0.071	0.519
15	0.357	0.212	0.11	0.321

PWM

	A	C	G	T
01	1.005	-2.004	0.115	-4.52
02	-4.977	-4.52	-4.207	1.378
03	-4.977	-4.207	1.371	-3.248
04	1.371	-4.207	-3.478	-4.207
05	-2.705	1.195	-0.672	-2.13
06	-1.384	-3.15	-1.946	1.271
07	-1.538	1.25	-1.919	-1.919
08	1.245	-2.903	-1.236	-1.7
09	-3.248	-4.977	1.358	-2.705
10	-3.616	1.356	-2.647	-3.777
11	1.244	-2.979	-1.236	-1.657
12	0.049	-0.418	0.491	-0.418
13	0.14	-0.89	-0.406	0.573
14	0.17	-0.789	-1.236	0.727
15	0.355	-0.162	-0.815	0.248

Standard thresholds

P-value	Threshold
0.001	1.33801
0.0005	2.72016
0.0001	5.62801