NFAC4.H14INVIVO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFAC4.H14INVIVO.0.P.D
Gene (human)	NFATC4 (GeneCards)
Gene synonyms (human)	NFAT3
Gene (mouse)	Nfatc4
Gene synonyms (mouse)	Nfat3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	10
Consensus	dGGAAARhdW
GC content	35.69%
Information content (bits; total / per base)	11.136 / 1.114
Data sources	ChIP-Seq
Aligned words	19
Previous names	NFAC4.H12INVIVO.0.P.D; NFAC4_HUMAN.H11MO.0.C; NFAC4_HUMAN.H10MO.C; NFAC4_f1

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (4)	0.529	0.532	0.347	0.348	0.562	0.577	1.172	1.201	0.0	0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.945	0.901	0.936	0.892	0.884	0.849
Overall, 4 experiments	best	0.973	0.949	0.966	0.941	0.952	0.924
Methyl HT-SELEX, 2 experiments	median	0.945	0.901	0.936	0.892	0.884	0.849
Methyl HT-SELEX, 2 experiments	best	0.963	0.929	0.957	0.924	0.932	0.899
Non-Methyl HT-SELEX, 2 experiments	median	0.927	0.881	0.914	0.868	0.855	0.824
Non-Methyl HT-SELEX, 2 experiments	best	0.973	0.949	0.966	0.941	0.952	0.924

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Rel homology region (RHR) factors {6.1} (TFClass)
TF family	NFAT-related {6.1.3} (TFClass)
TF subfamily	{6.1.3.0} (TFClass)
TFClass ID	TFClass: 6.1.3.0.4
HGNC	HGNC:7778
MGI	MGI:1920431
EntrezGene (human)	GeneID:4776 (SSTAR profile)
EntrezGene (mouse)	GeneID:73181 (SSTAR profile)
UniProt ID (human)	NFAC4_HUMAN
UniProt ID (mouse)	NFAC4_MOUSE
UniProt AC (human)	Q14934 (TFClass)
UniProt AC (mouse)	Q8K120 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	NFAC4.H14INVIVO.0.P.D.pcm
PWM	NFAC4.H14INVIVO.0.P.D.pwm
PFM	NFAC4.H14INVIVO.0.P.D.pfm
Threshold to P-value map	NFAC4.H14INVIVO.0.P.D.thr
Motif in other formats
JASPAR format	NFAC4.H14INVIVO.0.P.D_jaspar_format.txt
MEME format	NFAC4.H14INVIVO.0.P.D_meme_format.meme
Transfac format	NFAC4.H14INVIVO.0.P.D_transfac_format.txt
Homer format	NFAC4.H14INVIVO.0.P.D_homer_format_0.001.txt NFAC4.H14INVIVO.0.P.D_homer_format_0.0005.txt NFAC4.H14INVIVO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	7.893	2.723	3.933	4.483
02	0.0	0.0	18.04	0.99
03	0.0	0.0	19.03	0.0
04	19.03	0.0	0.0	0.0
05	19.03	0.0	0.0	0.0
06	19.03	0.0	0.0	0.0
07	11.99	2.97	3.08	0.99
08	3.96	4.95	2.09	8.03
09	3.08	2.97	4.07	8.91
10	5.94	0.0	4.07	9.02

PFM

	A	C	G	T
01	0.415	0.143	0.207	0.236
02	0.0	0.0	0.948	0.052
03	0.0	0.0	1.0	0.0
04	1.0	0.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.63	0.156	0.162	0.052
08	0.208	0.26	0.11	0.422
09	0.162	0.156	0.214	0.468
10	0.312	0.0	0.214	0.474

PWM

	A	C	G	T
01	0.451	-0.463	-0.163	-0.051
02	-2.009	-2.009	1.229	-1.158
03	-2.009	-2.009	1.28	-2.009
04	1.28	-2.009	-2.009	-2.009
05	1.28	-2.009	-2.009	-2.009
06	1.28	-2.009	-2.009	-2.009
07	0.84	-0.394	-0.364	-1.158
08	-0.157	0.034	-0.665	0.467
09	-0.364	-0.394	-0.134	0.563
10	0.195	-2.009	-0.134	0.574

Standard thresholds

P-value	Threshold
0.001	4.89599
0.0005	5.700815
0.0001	7.234575