| Motif | NACC2.H14INVIVO.0.PSGIB.A |
| Gene (human) | NACC2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nacc2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | NACC2.H14INVIVO.0.PSGIB.A |
| Gene (human) | NACC2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nacc2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 15 |
| Consensus | WdKKdRCATGTRWSW |
| GC content | 41.59% |
| Information content (bits; total / per base) | 13.52 / 0.901 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM |
| Aligned words | 138 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 3 (3) | 0.865 | 0.866 | 0.742 | 0.767 | 0.773 | 0.789 | 35.409 | 71.921 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 4 experiments | median | 0.72 | 0.68 | 0.64 | 0.62 | 0.582 | 0.578 |
| best | 0.988 | 0.98 | 0.978 | 0.967 | 0.957 | 0.94 | |
| Lysate, 1 experiments | median | 0.817 | 0.776 | 0.699 | 0.68 | 0.612 | 0.614 |
| best | 0.817 | 0.776 | 0.699 | 0.68 | 0.612 | 0.614 | |
| IVT, 2 experiments | median | 0.58 | 0.555 | 0.552 | 0.539 | 0.534 | 0.527 |
| best | 0.624 | 0.584 | 0.581 | 0.56 | 0.551 | 0.541 | |
| GFPIVT, 1 experiments | median | 0.988 | 0.98 | 0.978 | 0.967 | 0.957 | 0.94 |
| best | 0.988 | 0.98 | 0.978 | 0.967 | 0.957 | 0.94 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 2 experiments | median | 75.456 | 0.793 | 0.872 | 0.729 |
| best | 223.602 | 0.842 | 0.93 | 0.822 | |
| Lysate, 1 experiments | median | 166.409 | 0.829 | 0.913 | 0.792 |
| best | 166.409 | 0.829 | 0.913 | 0.792 | |
| GFPIVT, 1 experiments | median | 46.3 | 0.737 | 0.826 | 0.702 |
| best | 223.602 | 0.842 | 0.93 | 0.822 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.797 | 0.768 | 0.748 | 0.727 | 0.7 | 0.683 |
| best | 0.959 | 0.935 | 0.926 | 0.894 | 0.856 | 0.827 | |
| PBM benchmarking | auROC, QNZS | auPR, QNZS | auROC, SD | auPR, SD | |
|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.88 | 0.034 | 0.836 | 0.045 |
| best | 0.885 | 0.034 | 0.89 | 0.051 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Other {3.0} (TFClass) |
| TF family | BEN {3.0.257} (TFClass) |
| TF subfamily | {3.0.257.0} (TFClass) |
| TFClass ID | TFClass: 3.0.257.0.1 |
| HGNC | |
| MGI | |
| EntrezGene (human) | |
| EntrezGene (mouse) | |
| UniProt ID (human) | NACC2_HUMAN |
| UniProt ID (mouse) | NACC2_MOUSE |
| UniProt AC (human) | Q96BF6 (TFClass) |
| UniProt AC (mouse) | Q9DCM7 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 0 mouse |
| HT-SELEX | 4 overall: 1 Lysate, 2 IVT, 1 GFPIVT |
| Genomic HT-SELEX | 2 overall: 1 Lysate, 0 IVT, 1 GFPIVT |
| SMiLE-Seq | 2 |
| PBM | 4 |
| PCM | NACC2.H14INVIVO.0.PSGIB.A.pcm |
| PWM | NACC2.H14INVIVO.0.PSGIB.A.pwm |
| PFM | NACC2.H14INVIVO.0.PSGIB.A.pfm |
| Threshold to P-value map | NACC2.H14INVIVO.0.PSGIB.A.thr |
| Motif in other formats | |
| JASPAR format | NACC2.H14INVIVO.0.PSGIB.A_jaspar_format.txt |
| MEME format | NACC2.H14INVIVO.0.PSGIB.A_meme_format.meme |
| Transfac format | NACC2.H14INVIVO.0.PSGIB.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 37.0 | 4.0 | 16.0 | 81.0 |
| 02 | 19.0 | 6.0 | 69.0 | 44.0 |
| 03 | 15.0 | 3.0 | 36.0 | 84.0 |
| 04 | 6.0 | 7.0 | 70.0 | 55.0 |
| 05 | 22.0 | 14.0 | 46.0 | 56.0 |
| 06 | 82.0 | 5.0 | 47.0 | 4.0 |
| 07 | 4.0 | 130.0 | 1.0 | 3.0 |
| 08 | 128.0 | 4.0 | 3.0 | 3.0 |
| 09 | 3.0 | 2.0 | 4.0 | 129.0 |
| 10 | 11.0 | 1.0 | 125.0 | 1.0 |
| 11 | 1.0 | 13.0 | 1.0 | 123.0 |
| 12 | 30.0 | 7.0 | 98.0 | 3.0 |
| 13 | 31.0 | 8.0 | 2.0 | 97.0 |
| 14 | 14.0 | 16.0 | 98.0 | 10.0 |
| 15 | 16.0 | 12.0 | 13.0 | 97.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.268 | 0.029 | 0.116 | 0.587 |
| 02 | 0.138 | 0.043 | 0.5 | 0.319 |
| 03 | 0.109 | 0.022 | 0.261 | 0.609 |
| 04 | 0.043 | 0.051 | 0.507 | 0.399 |
| 05 | 0.159 | 0.101 | 0.333 | 0.406 |
| 06 | 0.594 | 0.036 | 0.341 | 0.029 |
| 07 | 0.029 | 0.942 | 0.007 | 0.022 |
| 08 | 0.928 | 0.029 | 0.022 | 0.022 |
| 09 | 0.022 | 0.014 | 0.029 | 0.935 |
| 10 | 0.08 | 0.007 | 0.906 | 0.007 |
| 11 | 0.007 | 0.094 | 0.007 | 0.891 |
| 12 | 0.217 | 0.051 | 0.71 | 0.022 |
| 13 | 0.225 | 0.058 | 0.014 | 0.703 |
| 14 | 0.101 | 0.116 | 0.71 | 0.072 |
| 15 | 0.116 | 0.087 | 0.094 | 0.703 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.068 | -1.921 | -0.729 | 0.834 |
| 02 | -0.569 | -1.598 | 0.676 | 0.236 |
| 03 | -0.789 | -2.133 | 0.041 | 0.869 |
| 04 | -1.598 | -1.468 | 0.69 | 0.453 |
| 05 | -0.431 | -0.853 | 0.279 | 0.471 |
| 06 | 0.846 | -1.746 | 0.3 | -1.921 |
| 07 | -1.921 | 1.301 | -2.773 | -2.133 |
| 08 | 1.286 | -1.921 | -2.133 | -2.133 |
| 09 | -2.133 | -2.403 | -1.921 | 1.293 |
| 10 | -1.072 | -2.773 | 1.262 | -2.773 |
| 11 | -2.773 | -0.921 | -2.773 | 1.246 |
| 12 | -0.135 | -1.468 | 1.021 | -2.133 |
| 13 | -0.103 | -1.353 | -2.403 | 1.011 |
| 14 | -0.853 | -0.729 | 1.021 | -1.157 |
| 15 | -0.729 | -0.993 | -0.921 | 1.011 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.04766 |
| 0.0005 | 4.99816 |
| 0.0001 | 6.99526 |