MRFL.H14INVIVO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MRFL.H14INVIVO.0.PSG.A
Gene (human)	MYRFL (GeneCards)
Gene synonyms (human)
Gene (mouse)	Myrfl
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	21
Consensus	GTRMCASSYdGdRMYRKShMY
GC content	63.22%
Information content (bits; total / per base)	14.937 / 0.711
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	497
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.863	0.868	0.757	0.765	0.73	0.734	113.361	115.119

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Lysate, 2 experiments	median	1.0	1.0	0.999	0.998	0.869	0.888
Lysate, 2 experiments	best	1.0	1.0	0.999	0.998	0.878	0.895

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 2 experiments	median	184.357	0.914	0.936	0.91
Lysate, 2 experiments	best	486.114	0.974	0.979	0.962

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	NDT80 domain factors {6.6} (TFClass)
TF family	MYRF-related {6.6.1} (TFClass)
TF subfamily	{6.6.1.0} (TFClass)
TFClass ID	TFClass: 6.6.1.0.255
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	MRFL_HUMAN
UniProt ID (mouse)	MRFL_MOUSE
UniProt AC (human)	Q96LU7 (TFClass)
UniProt AC (mouse)	Q3UN70 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
Genomic HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	MRFL.H14INVIVO.0.PSG.A.pcm
PWM	MRFL.H14INVIVO.0.PSG.A.pwm
PFM	MRFL.H14INVIVO.0.PSG.A.pfm
Threshold to P-value map	MRFL.H14INVIVO.0.PSG.A.thr
Motif in other formats
JASPAR format	MRFL.H14INVIVO.0.PSG.A_jaspar_format.txt
MEME format	MRFL.H14INVIVO.0.PSG.A_meme_format.meme
Transfac format	MRFL.H14INVIVO.0.PSG.A_transfac_format.txt
Homer format	MRFL.H14INVIVO.0.PSG.A_homer_format_0.001.txt MRFL.H14INVIVO.0.PSG.A_homer_format_0.0005.txt MRFL.H14INVIVO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	20.0	6.0	469.0	2.0
02	22.0	25.0	35.0	415.0
03	152.0	11.0	327.0	7.0
04	53.0	353.0	43.0	48.0
05	28.0	425.0	14.0	30.0
06	420.0	10.0	26.0	41.0
07	29.0	122.0	289.0	57.0
08	13.0	185.0	232.0	67.0
09	51.0	326.0	51.0	69.0
10	178.0	42.0	120.0	157.0
11	13.0	59.0	422.0	3.0
12	86.0	75.0	84.0	252.0
13	66.0	27.0	392.0	12.0
14	254.0	208.0	22.0	13.0
15	14.0	345.0	27.0	111.0
16	270.0	18.0	156.0	53.0
17	16.0	15.0	224.0	242.0
18	16.0	281.0	165.0	35.0
19	96.0	219.0	50.0	132.0
20	136.0	296.0	30.0	35.0
21	37.0	305.0	67.0	88.0

PFM

	A	C	G	T
01	0.04	0.012	0.944	0.004
02	0.044	0.05	0.07	0.835
03	0.306	0.022	0.658	0.014
04	0.107	0.71	0.087	0.097
05	0.056	0.855	0.028	0.06
06	0.845	0.02	0.052	0.082
07	0.058	0.245	0.581	0.115
08	0.026	0.372	0.467	0.135
09	0.103	0.656	0.103	0.139
10	0.358	0.085	0.241	0.316
11	0.026	0.119	0.849	0.006
12	0.173	0.151	0.169	0.507
13	0.133	0.054	0.789	0.024
14	0.511	0.419	0.044	0.026
15	0.028	0.694	0.054	0.223
16	0.543	0.036	0.314	0.107
17	0.032	0.03	0.451	0.487
18	0.032	0.565	0.332	0.07
19	0.193	0.441	0.101	0.266
20	0.274	0.596	0.06	0.07
21	0.074	0.614	0.135	0.177

PWM

	A	C	G	T
01	-1.764	-2.813	1.319	-3.567
02	-1.675	-1.556	-1.236	1.197
03	0.199	-2.305	0.96	-2.689
04	-0.836	1.036	-1.038	-0.932
05	-1.449	1.221	-2.091	-1.383
06	1.209	-2.388	-1.519	-1.084
07	-1.415	-0.018	0.837	-0.765
08	-2.157	0.394	0.619	-0.607
09	-0.873	0.957	-0.873	-0.578
10	0.356	-1.061	-0.034	0.231
11	-2.157	-0.731	1.214	-3.319
12	-0.362	-0.497	-0.386	0.701
13	-0.622	-1.483	1.141	-2.228
14	0.709	0.51	-1.675	-2.157
15	-2.091	1.013	-1.483	-0.111
16	0.769	-1.862	0.225	-0.836
17	-1.97	-2.028	0.584	0.661
18	-1.97	0.809	0.281	-1.236
19	-0.254	0.561	-0.892	0.06
20	0.089	0.861	-1.383	-1.236
21	-1.183	0.891	-0.607	-0.34

Standard thresholds

P-value	Threshold
0.001	3.47486
0.0005	4.49466
0.0001	6.65291