MLXPL.H14CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MLXPL.H14CORE.0.S.B
Gene (human)	MLXIPL (GeneCards)
Gene synonyms (human)	BHLHD14, MIO, WBSCR14
Gene (mouse)	Mlxipl
Gene synonyms (mouse)	Mio, Wbscr14
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nhddKCACGTGnhn
GC content	49.95%
Information content (bits; total / per base)	13.506 / 0.965
Data sources	HT-SELEX
Aligned words	2496
Previous names	MLXPL.H12CORE.0.S.B

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.632	0.636	0.577	0.577	0.547	0.548
Non-Methyl HT-SELEX, 2 experiments	best	0.645	0.65	0.581	0.583	0.548	0.552

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MONDOlike {1.2.6.6} (TFClass)
TFClass ID	TFClass: 1.2.6.6.3
HGNC	HGNC:12744
MGI	MGI:1927999
EntrezGene (human)	GeneID:51085 (SSTAR profile)
EntrezGene (mouse)	GeneID:58805 (SSTAR profile)
UniProt ID (human)	MLXPL_HUMAN
UniProt ID (mouse)	MLXPL_MOUSE
UniProt AC (human)	Q9NP71 (TFClass)
UniProt AC (mouse)	Q99MZ3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	MLXPL.H14CORE.0.S.B.pcm
PWM	MLXPL.H14CORE.0.S.B.pwm
PFM	MLXPL.H14CORE.0.S.B.pfm
Threshold to P-value map	MLXPL.H14CORE.0.S.B.thr
Motif in other formats
JASPAR format	MLXPL.H14CORE.0.S.B_jaspar_format.txt
MEME format	MLXPL.H14CORE.0.S.B_meme_format.meme
Transfac format	MLXPL.H14CORE.0.S.B_transfac_format.txt
Homer format	MLXPL.H14CORE.0.S.B_homer_format_0.001.txt MLXPL.H14CORE.0.S.B_homer_format_0.0005.txt MLXPL.H14CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	644.25	534.25	581.25	736.25
02	428.5	426.5	399.5	1241.5
03	354.0	185.0	1332.0	625.0
04	1339.0	140.0	626.0	391.0
05	147.0	103.0	332.0	1914.0
06	3.0	2489.0	1.0	3.0
07	2494.0	1.0	1.0	0.0
08	1.0	2491.0	1.0	3.0
09	1.0	0.0	2491.0	4.0
10	7.0	11.0	8.0	2470.0
11	75.0	14.0	2369.0	38.0
12	656.0	679.0	344.0	817.0
13	761.75	517.75	291.75	924.75
14	820.5	746.5	337.5	591.5

PFM

	A	C	G	T
01	0.258	0.214	0.233	0.295
02	0.172	0.171	0.16	0.497
03	0.142	0.074	0.534	0.25
04	0.536	0.056	0.251	0.157
05	0.059	0.041	0.133	0.767
06	0.001	0.997	0.0	0.001
07	0.999	0.0	0.0	0.0
08	0.0	0.998	0.0	0.001
09	0.0	0.0	0.998	0.002
10	0.003	0.004	0.003	0.99
11	0.03	0.006	0.949	0.015
12	0.263	0.272	0.138	0.327
13	0.305	0.207	0.117	0.37
14	0.329	0.299	0.135	0.237

PWM

	A	C	G	T
01	0.032	-0.155	-0.071	0.165
02	-0.374	-0.379	-0.444	0.686
03	-0.564	-1.208	0.757	0.002
04	0.762	-1.484	0.003	-0.466
05	-1.436	-1.786	-0.628	1.119
06	-4.839	1.381	-5.356	-4.839
07	1.383	-5.356	-5.356	-5.769
08	-5.356	1.382	-5.356	-4.839
09	-5.356	-5.769	1.382	-4.655
10	-4.247	-3.878	-4.141	1.373
11	-2.096	-3.669	1.332	-2.752
12	0.05	0.084	-0.593	0.269
13	0.199	-0.186	-0.757	0.392
14	0.273	0.179	-0.612	-0.053

Standard thresholds

P-value	Threshold
0.001	2.62186
0.0005	3.93606
0.0001	7.12656