| Motif | MEIS3.H14INVIVO.0.SM.D |
| Gene (human) | MEIS3 (GeneCards) |
| Gene synonyms (human) | MRG2 |
| Gene (mouse) | Meis3 |
| Gene synonyms (mouse) | Mrg2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | MEIS3.H14INVIVO.0.SM.D |
| Gene (human) | MEIS3 (GeneCards) |
| Gene synonyms (human) | MRG2 |
| Gene (mouse) | Meis3 |
| Gene synonyms (mouse) | Mrg2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 8 |
| Consensus | nTGACAbn |
| GC content | 45.97% |
| Information content (bits; total / per base) | 10.159 / 1.27 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8090 |
| Previous names | MEIS3.H12INVIVO.0.SM.D |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.992 | 0.989 | 0.977 | 0.969 | 0.9 | 0.895 |
| best | 0.999 | 0.999 | 0.998 | 0.998 | 0.993 | 0.991 | |
| Methyl HT-SELEX, 1 experiments | median | 0.998 | 0.997 | 0.991 | 0.988 | 0.982 | 0.975 |
| best | 0.998 | 0.997 | 0.991 | 0.988 | 0.982 | 0.975 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.988 | 0.983 | 0.967 | 0.955 | 0.879 | 0.872 |
| best | 0.999 | 0.999 | 0.998 | 0.998 | 0.993 | 0.991 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.968 | 0.881 | 0.954 | 0.582 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | TALE-type HD {3.1.4} (TFClass) |
| TF subfamily | MEIS {3.1.4.2} (TFClass) |
| TFClass ID | TFClass: 3.1.4.2.3 |
| HGNC | HGNC:29537 |
| MGI | MGI:108519 |
| EntrezGene (human) | GeneID:56917 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17537 (SSTAR profile) |
| UniProt ID (human) | MEIS3_HUMAN |
| UniProt ID (mouse) | MEIS3_MOUSE |
| UniProt AC (human) | Q99687 (TFClass) |
| UniProt AC (mouse) | P97368 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | MEIS3.H14INVIVO.0.SM.D.pcm |
| PWM | MEIS3.H14INVIVO.0.SM.D.pwm |
| PFM | MEIS3.H14INVIVO.0.SM.D.pfm |
| Threshold to P-value map | MEIS3.H14INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | MEIS3.H14INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | MEIS3.H14INVIVO.0.SM.D_meme_format.meme |
| Transfac format | MEIS3.H14INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2096.0 | 1979.0 | 1648.0 | 2367.0 |
| 02 | 0.0 | 0.0 | 0.0 | 8090.0 |
| 03 | 0.0 | 0.0 | 8090.0 | 0.0 |
| 04 | 8090.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.0 | 8090.0 | 0.0 | 0.0 |
| 06 | 8090.0 | 0.0 | 0.0 | 0.0 |
| 07 | 1449.0 | 1540.0 | 3428.0 | 1673.0 |
| 08 | 1618.75 | 2293.75 | 2682.75 | 1494.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.259 | 0.245 | 0.204 | 0.293 |
| 02 | 0.0 | 0.0 | 0.0 | 1.0 |
| 03 | 0.0 | 0.0 | 1.0 | 0.0 |
| 04 | 1.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.0 | 1.0 | 0.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.179 | 0.19 | 0.424 | 0.207 |
| 08 | 0.2 | 0.284 | 0.332 | 0.185 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.036 | -0.022 | -0.205 | 0.157 |
| 02 | -6.802 | -6.802 | -6.802 | 1.385 |
| 03 | -6.802 | -6.802 | 1.385 | -6.802 |
| 04 | 1.385 | -6.802 | -6.802 | -6.802 |
| 05 | -6.802 | 1.385 | -6.802 | -6.802 |
| 06 | 1.385 | -6.802 | -6.802 | -6.802 |
| 07 | -0.333 | -0.272 | 0.527 | -0.189 |
| 08 | -0.222 | 0.126 | 0.282 | -0.302 |
| P-value | Threshold |
|---|---|
| 0.001 | -0.029285 |
| 0.0005 | 6.760695 |
| 0.0001 | 7.469465 |