MotifMEIS2.H14INVIVO.2.SM.B
Gene (human)MEIS2
(GeneCards)
Gene synonyms (human)MRG1
Gene (mouse)Meis2
Gene synonyms (mouse)Mrg1, Stra10
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length14
ConsensusnWTGACAGCTKdhh
GC content48.32%
Information content (bits; total / per base)16.229 / 1.159
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words1448
Previous namesMEIS2.H12INVIVO.2.SM.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.679 0.69 0.544 0.561 0.614 0.642 1.506 1.643 67.678 100.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.963 0.946 0.899 0.876 0.789 0.778
best 0.997 0.995 0.993 0.989 0.983 0.977
Methyl HT-SELEX, 2 experiments median 0.963 0.946 0.899 0.876 0.789 0.778
best 0.972 0.959 0.915 0.895 0.789 0.786
Non-Methyl HT-SELEX, 6 experiments median 0.908 0.883 0.837 0.812 0.735 0.727
best 0.997 0.995 0.993 0.989 0.983 0.977

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.732 3.646 0.18 0.182

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.686 0.315 0.399 0.166
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyMEIS {3.1.4.2} (TFClass)
TFClass IDTFClass: 3.1.4.2.2
HGNCHGNC:7001
MGIMGI:108564
EntrezGene (human)GeneID:4212
(SSTAR profile)
EntrezGene (mouse)GeneID:17536
(SSTAR profile)
UniProt ID (human)MEIS2_HUMAN
UniProt ID (mouse)MEIS2_MOUSE
UniProt AC (human)O14770
(TFClass)
UniProt AC (mouse)P97367
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01345.5314.5330.5457.5
02332.75146.7598.75869.75
030.00.00.01448.0
040.00.01448.00.0
051448.00.00.00.0
060.01448.00.00.0
071448.00.00.00.0
080.00.01447.01.0
096.01068.0373.01.0
106.0152.013.01277.0
11148.068.0863.0369.0
12321.0128.0373.0626.0
13228.75826.75150.75241.75
14669.75346.75198.75232.75
PFM
ACGT
010.2390.2170.2280.316
020.230.1010.0680.601
030.00.00.01.0
040.00.01.00.0
051.00.00.00.0
060.01.00.00.0
071.00.00.00.0
080.00.00.9990.001
090.0040.7380.2580.001
100.0040.1050.0090.882
110.1020.0470.5960.255
120.2220.0880.2580.432
130.1580.5710.1040.167
140.4630.2390.1370.161
PWM
ACGT
01-0.046-0.14-0.0910.233
02-0.084-0.896-1.2860.874
03-5.298-5.298-5.2981.383
04-5.298-5.2981.383-5.298
051.383-5.298-5.298-5.298
06-5.2981.383-5.298-5.298
071.383-5.298-5.298-5.298
08-5.298-5.2981.382-4.86
09-3.841.0790.03-4.86
10-3.84-0.861-3.2011.257
11-0.887-1.6510.8660.019
12-0.12-1.0310.030.546
13-0.4560.823-0.869-0.401
140.613-0.043-0.595-0.439
Standard thresholds
P-value Threshold
0.001 0.28731
0.0005 2.13166
0.0001 5.20522