| Motif | MEF2D.H14INVITRO.0.PS.A |
| Gene (human) | MEF2D (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Mef2d |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | MEF2D.H14INVITRO.0.PS.A |
| Gene (human) | MEF2D (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Mef2d |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 19 |
| Consensus | nnnnnddKCTATTWATAGh |
| GC content | 33.59% |
| Information content (bits; total / per base) | 16.338 / 0.86 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 9980 |
| Previous names | MEF2D.H12INVITRO.0.PS.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (7) | 0.672 | 0.704 | 0.628 | 0.655 | 0.711 | 0.741 | 3.132 | 3.296 | 94.721 | 130.678 |
| Mouse | 8 (46) | 0.872 | 0.926 | 0.82 | 0.885 | 0.884 | 0.93 | 4.199 | 5.098 | 202.833 | 524.745 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 3 experiments | median | 0.737 | 0.743 | 0.639 | 0.625 | 0.573 | 0.577 |
| best | 0.98 | 0.98 | 0.725 | 0.77 | 0.583 | 0.646 | |
| Methyl HT-SELEX, 1 experiments | median | 0.737 | 0.703 | 0.639 | 0.625 | 0.573 | 0.577 |
| best | 0.737 | 0.703 | 0.639 | 0.625 | 0.573 | 0.577 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.851 | 0.861 | 0.655 | 0.694 | 0.557 | 0.604 |
| best | 0.98 | 0.98 | 0.725 | 0.77 | 0.583 | 0.646 | |
| TF superclass | alpha-Helices exposed by beta-structures {5} (TFClass) |
| TF class | MADS box factors {5.1} (TFClass) |
| TF family | Regulators of differentiation {5.1.1} (TFClass) |
| TF subfamily | MEF2 {5.1.1.1} (TFClass) |
| TFClass ID | TFClass: 5.1.1.1.4 |
| HGNC | HGNC:6997 |
| MGI | MGI:99533 |
| EntrezGene (human) | GeneID:4209 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17261 (SSTAR profile) |
| UniProt ID (human) | MEF2D_HUMAN |
| UniProt ID (mouse) | MEF2D_MOUSE |
| UniProt AC (human) | Q14814 (TFClass) |
| UniProt AC (mouse) | Q63943 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 8 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | MEF2D.H14INVITRO.0.PS.A.pcm |
| PWM | MEF2D.H14INVITRO.0.PS.A.pwm |
| PFM | MEF2D.H14INVITRO.0.PS.A.pfm |
| Threshold to P-value map | MEF2D.H14INVITRO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | MEF2D.H14INVITRO.0.PS.A_jaspar_format.txt |
| MEME format | MEF2D.H14INVITRO.0.PS.A_meme_format.meme |
| Transfac format | MEF2D.H14INVITRO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2262.5 | 2841.5 | 2418.5 | 2457.5 |
| 02 | 2211.25 | 2932.25 | 2398.25 | 2438.25 |
| 03 | 2156.0 | 3037.0 | 2555.0 | 2232.0 |
| 04 | 2391.0 | 2579.0 | 2655.0 | 2355.0 |
| 05 | 2561.0 | 2212.0 | 2967.0 | 2240.0 |
| 06 | 2867.0 | 1436.0 | 3718.0 | 1959.0 |
| 07 | 2871.0 | 911.0 | 2566.0 | 3632.0 |
| 08 | 873.0 | 311.0 | 4471.0 | 4325.0 |
| 09 | 52.0 | 9797.0 | 25.0 | 106.0 |
| 10 | 12.0 | 43.0 | 11.0 | 9914.0 |
| 11 | 9929.0 | 30.0 | 8.0 | 13.0 |
| 12 | 1982.0 | 6.0 | 5.0 | 7987.0 |
| 13 | 4172.0 | 0.0 | 1.0 | 5807.0 |
| 14 | 4925.0 | 3.0 | 6.0 | 5046.0 |
| 15 | 7277.0 | 27.0 | 19.0 | 2657.0 |
| 16 | 41.0 | 37.0 | 42.0 | 9860.0 |
| 17 | 9756.0 | 13.0 | 191.0 | 20.0 |
| 18 | 273.75 | 111.75 | 9465.75 | 128.75 |
| 19 | 4046.5 | 2557.5 | 1277.5 | 2098.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.227 | 0.285 | 0.242 | 0.246 |
| 02 | 0.222 | 0.294 | 0.24 | 0.244 |
| 03 | 0.216 | 0.304 | 0.256 | 0.224 |
| 04 | 0.24 | 0.258 | 0.266 | 0.236 |
| 05 | 0.257 | 0.222 | 0.297 | 0.224 |
| 06 | 0.287 | 0.144 | 0.373 | 0.196 |
| 07 | 0.288 | 0.091 | 0.257 | 0.364 |
| 08 | 0.087 | 0.031 | 0.448 | 0.433 |
| 09 | 0.005 | 0.982 | 0.003 | 0.011 |
| 10 | 0.001 | 0.004 | 0.001 | 0.993 |
| 11 | 0.995 | 0.003 | 0.001 | 0.001 |
| 12 | 0.199 | 0.001 | 0.001 | 0.8 |
| 13 | 0.418 | 0.0 | 0.0 | 0.582 |
| 14 | 0.493 | 0.0 | 0.001 | 0.506 |
| 15 | 0.729 | 0.003 | 0.002 | 0.266 |
| 16 | 0.004 | 0.004 | 0.004 | 0.988 |
| 17 | 0.978 | 0.001 | 0.019 | 0.002 |
| 18 | 0.027 | 0.011 | 0.948 | 0.013 |
| 19 | 0.405 | 0.256 | 0.128 | 0.21 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.098 | 0.13 | -0.031 | -0.015 |
| 02 | -0.121 | 0.161 | -0.04 | -0.023 |
| 03 | -0.146 | 0.196 | 0.024 | -0.111 |
| 04 | -0.043 | 0.033 | 0.062 | -0.058 |
| 05 | 0.026 | -0.12 | 0.173 | -0.108 |
| 06 | 0.139 | -0.552 | 0.399 | -0.242 |
| 07 | 0.14 | -1.006 | 0.028 | 0.375 |
| 08 | -1.048 | -2.076 | 0.583 | 0.55 |
| 09 | -3.828 | 1.367 | -4.516 | -3.138 |
| 10 | -5.163 | -4.01 | -5.235 | 1.379 |
| 11 | 1.38 | -4.348 | -5.491 | -5.095 |
| 12 | -0.23 | -5.706 | -5.835 | 1.163 |
| 13 | 0.514 | -6.989 | -6.628 | 0.844 |
| 14 | 0.68 | -6.155 | -5.706 | 0.704 |
| 15 | 1.07 | -4.445 | -4.764 | 0.063 |
| 16 | -4.055 | -4.152 | -4.032 | 1.374 |
| 17 | 1.363 | -5.095 | -2.559 | -4.718 |
| 18 | -2.202 | -3.086 | 1.333 | -2.947 |
| 19 | 0.483 | 0.025 | -0.669 | -0.173 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.35116 |
| 0.0005 | 1.85351 |
| 0.0001 | 5.51271 |