MotifMEF2B.H14INVIVO.1.SM.B
Gene (human)MEF2B
(GeneCards)
Gene synonyms (human)XMEF2
Gene (mouse)Mef2b
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusnhSWTWCCWWAWhbGKhn
GC content43.41%
Information content (bits; total / per base)12.681 / 0.704
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9895
Previous namesMEF2B.H12INVIVO.1.SM.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 16 (100) 0.7 0.763 0.534 0.614 0.613 0.68 1.535 1.838 56.576 160.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.98 0.974 0.914 0.899 0.794 0.79
best 0.999 0.998 0.988 0.985 0.921 0.917
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.988 0.985 0.921 0.917
best 0.999 0.998 0.988 0.985 0.921 0.917
Non-Methyl HT-SELEX, 2 experiments median 0.753 0.751 0.709 0.705 0.645 0.647
best 0.98 0.974 0.914 0.899 0.794 0.79

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.036 2.414 0.112 0.079

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.775 0.336 0.422 0.275
batch 2 0.788 0.354 0.559 0.444
TF superclassalpha-Helices exposed by beta-structures {5} (TFClass)
TF classMADS box factors {5.1} (TFClass)
TF familyRegulators of differentiation {5.1.1} (TFClass)
TF subfamilyMEF2 {5.1.1.1} (TFClass)
TFClass IDTFClass: 5.1.1.1.2
HGNCHGNC:6995
MGIMGI:104526
EntrezGene (human)GeneID:100271849
(SSTAR profile)
GeneID:4207
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)MEF2B_HUMAN
UniProt ID (mouse)MEF2B_MOUSE
UniProt AC (human)Q02080
(TFClass)
UniProt AC (mouse)O55087
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 16 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
012535.52232.52983.52143.5
021263.03839.01054.03739.0
03563.0943.07865.0524.0
041371.0607.01220.06697.0
05892.0379.0380.08244.0
065892.0403.01462.02138.0
0717.09850.021.07.0
086.09271.037.0581.0
096393.01054.0717.01731.0
103680.0488.0476.05251.0
118005.048.047.01795.0
122161.0281.0110.07343.0
132783.01746.01209.04157.0
141263.01634.02864.04134.0
151761.0161.07787.0186.0
16565.0404.07392.01534.0
173653.03233.01329.01680.0
183793.52151.51646.52303.5
PFM
ACGT
010.2560.2260.3020.217
020.1280.3880.1070.378
030.0570.0950.7950.053
040.1390.0610.1230.677
050.090.0380.0380.833
060.5950.0410.1480.216
070.0020.9950.0020.001
080.0010.9370.0040.059
090.6460.1070.0720.175
100.3720.0490.0480.531
110.8090.0050.0050.181
120.2180.0280.0110.742
130.2810.1760.1220.42
140.1280.1650.2890.418
150.1780.0160.7870.019
160.0570.0410.7470.155
170.3690.3270.1340.17
180.3830.2170.1660.233
PWM
ACGT
010.025-0.1030.187-0.143
02-0.6710.439-0.8520.413
03-1.477-0.9631.156-1.549
04-0.589-1.402-0.7060.995
05-1.018-1.871-1.8681.203
060.867-1.81-0.525-0.146
07-4.8541.381-4.666-5.584
08-5.6981.32-4.143-1.446
090.949-0.852-1.236-0.357
100.397-1.619-1.6440.752
111.174-3.896-3.916-0.32
12-0.135-2.168-3.0931.087
130.118-0.348-0.7150.519
14-0.671-0.4140.1460.513
15-0.339-2.7191.146-2.576
16-1.474-1.8071.094-0.477
170.390.267-0.621-0.387
180.427-0.139-0.407-0.071
Standard thresholds
P-value Threshold
0.001 3.96791
0.0005 4.98386
0.0001 7.05401