MotifMAX.H14CORE.2.S.C
Gene (human)MAX
(GeneCards)
Gene synonyms (human)BHLHD4
Gene (mouse)Max
Gene synonyms (mouse)Myn
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length22
ConsensusnndbCACGTGvbnnnCACGYGn
GC content60.07%
Information content (bits; total / per base)20.336 / 0.924
Data sourcesHT-SELEX
Aligned words4815
Previous namesMAX.H12CORE.2.S.C

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 39 (261) 0.809 0.953 0.729 0.91 0.756 0.888 2.489 3.355 101.092 282.06
Mouse 6 (39) 0.786 0.918 0.711 0.853 0.751 0.834 2.422 2.927 97.886 249.721

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.997 0.996 0.992 0.988 0.933 0.933
best 1.0 1.0 1.0 0.999 0.997 0.997
Methyl HT-SELEX, 1 experiments median 0.98 0.971 0.956 0.939 0.893 0.872
best 0.98 0.971 0.956 0.939 0.893 0.872
Non-Methyl HT-SELEX, 5 experiments median 0.998 0.997 0.993 0.989 0.967 0.958
best 1.0 1.0 1.0 0.999 0.997 0.997

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 25.713 21.169 0.284 0.251
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyMYC {1.2.6.5} (TFClass)
TFClass IDTFClass: 1.2.6.5.5
HGNCHGNC:6913
MGIMGI:96921
EntrezGene (human)GeneID:4149
(SSTAR profile)
EntrezGene (mouse)GeneID:17187
(SSTAR profile)
UniProt ID (human)MAX_HUMAN
UniProt ID (mouse)MAX_MOUSE
UniProt AC (human)P61244
(TFClass)
UniProt AC (mouse)P28574
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 39 human, 6 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
011254.751050.751354.751154.75
021537.5726.51388.51162.5
032193.0643.01280.0699.0
04577.02190.01325.0723.0
050.04815.00.00.0
064813.00.00.02.0
070.04813.00.02.0
083.00.04812.00.0
090.00.00.04815.0
100.00.04813.02.0
11863.01444.01927.0581.0
12784.01205.0793.02033.0
131458.01007.0810.01540.0
141800.01040.0962.01013.0
151003.01786.01146.0880.0
16433.04270.076.036.0
173967.0149.0628.071.0
18138.04437.029.0211.0
19297.0164.04351.03.0
2078.01132.0145.03460.0
2176.25157.253858.25723.25
22810.51383.51517.51103.5
PFM
ACGT
010.2610.2180.2810.24
020.3190.1510.2880.241
030.4550.1340.2660.145
040.120.4550.2750.15
050.01.00.00.0
061.00.00.00.0
070.01.00.00.0
080.0010.00.9990.0
090.00.00.01.0
100.00.01.00.0
110.1790.30.40.121
120.1630.250.1650.422
130.3030.2090.1680.32
140.3740.2160.20.21
150.2080.3710.2380.183
160.090.8870.0160.007
170.8240.0310.130.015
180.0290.9210.0060.044
190.0620.0340.9040.001
200.0160.2350.030.719
210.0160.0330.8010.15
220.1680.2870.3150.229
PWM
ACGT
010.041-0.1360.118-0.041
020.244-0.5040.143-0.035
030.599-0.6260.061-0.542
04-0.7330.5980.096-0.509
05-6.3441.385-6.344-6.344
061.385-6.344-6.344-5.679
07-6.3441.385-6.344-5.679
08-5.462-6.3441.384-6.344
09-6.344-6.344-6.3441.385
10-6.344-6.3441.385-5.679
11-0.3320.1820.47-0.727
12-0.4280.001-0.4160.523
130.191-0.178-0.3950.246
140.402-0.146-0.224-0.172
15-0.1820.394-0.049-0.313
16-1.0191.265-2.737-3.454
171.191-2.077-0.649-2.803
18-2.1521.303-3.657-1.733
19-1.394-1.9821.284-5.462
20-2.711-0.061-2.1041.055
21-2.734-2.0241.164-0.508
22-0.3950.1390.231-0.087
Standard thresholds
P-value Threshold
0.001 -3.29709
0.0005 -1.31374
0.0001 2.83151