MotifMAFA.H14CORE.0.PSM.A
Gene (human)MAFA
(GeneCards)
Gene synonyms (human)
Gene (mouse)Mafa
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length18
ConsensusndWhnTGCTGACdhndbn
GC content48.14%
Information content (bits; total / per base)13.63 / 0.757
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9977
Previous namesMAFA.H12CORE.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.752 0.785 0.683 0.702 0.712 0.759 2.241 2.381 92.119 107.538

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.996 0.992 0.989 0.939 0.935
best 0.998 0.998 0.995 0.993 0.955 0.951
Methyl HT-SELEX, 1 experiments median 0.997 0.995 0.989 0.985 0.923 0.919
best 0.997 0.995 0.989 0.985 0.923 0.919
Non-Methyl HT-SELEX, 1 experiments median 0.998 0.998 0.995 0.993 0.955 0.951
best 0.998 0.998 0.995 0.993 0.955 0.951

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.644 0.35 0.607 0.387
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilyLarge MAF {1.1.3.1} (TFClass)
TFClass IDTFClass: 1.1.3.1.2
HGNCHGNC:23145
MGIMGI:2673307
EntrezGene (human)GeneID:389692
(SSTAR profile)
EntrezGene (mouse)GeneID:378435
(SSTAR profile)
UniProt ID (human)MAFA_HUMAN
UniProt ID (mouse)MAFA_MOUSE
UniProt AC (human)Q8NHW3
(TFClass)
UniProt AC (mouse)Q8CF90
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
013617.01896.02504.01960.0
024786.0806.01893.02492.0
034687.0504.0856.03930.0
044314.0787.0640.04236.0
052809.01680.02026.03462.0
06287.01173.094.08423.0
0751.0100.09776.050.0
08110.09798.020.049.0
0970.057.055.09795.0
1081.024.09655.0217.0
119808.098.031.040.0
1282.08787.0507.0601.0
131691.0867.04413.03006.0
141346.04087.01286.03258.0
153896.02159.02030.01892.0
162477.01598.04100.01802.0
171419.754501.752404.751650.75
183092.253072.252175.251637.25
PFM
ACGT
010.3630.190.2510.196
020.480.0810.190.25
030.470.0510.0860.394
040.4320.0790.0640.425
050.2820.1680.2030.347
060.0290.1180.0090.844
070.0050.010.980.005
080.0110.9820.0020.005
090.0070.0060.0060.982
100.0080.0020.9680.022
110.9830.010.0030.004
120.0080.8810.0510.06
130.1690.0870.4420.301
140.1350.410.1290.327
150.390.2160.2030.19
160.2480.160.4110.181
170.1420.4510.2410.165
180.310.3080.2180.164
PWM
ACGT
010.371-0.2740.004-0.241
020.651-1.128-0.276-0.001
030.63-1.596-1.0680.454
040.547-1.152-1.3580.529
050.119-0.395-0.2080.328
06-2.155-0.753-3.2551.216
07-3.847-3.1951.365-3.866
08-3.1011.368-4.718-3.885
09-3.542-3.74-3.7741.367
10-3.4-4.5531.353-2.432
111.369-3.214-4.317-4.078
12-3.3881.259-1.59-1.42
13-0.388-1.0550.570.186
14-0.6160.493-0.6620.267
150.446-0.144-0.206-0.276
16-0.007-0.4450.497-0.325
17-0.5630.59-0.037-0.412
180.2150.208-0.137-0.42
Standard thresholds
P-value Threshold
0.001 3.17926
0.0005 4.38456
0.0001 6.85466