MAF.H14INVIVO.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAF.H14INVIVO.1.PSM.A
Gene (human)	MAF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Maf
Gene synonyms (mouse)	Maf2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	15
Consensus	nndhnTGCTGACbbn
GC content	51.65%
Information content (bits; total / per base)	13.651 / 0.91
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	322
Previous names	MAF.H12INVIVO.1.PSM.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.742	0.787	0.644	0.716	0.716	0.785	2.184	2.406	44.602	199.854
Mouse	4 (26)	0.779	0.839	0.695	0.753	0.781	0.841	2.406	2.787	230.903	334.553

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.938	0.915	0.816	0.798	0.692	0.696
Overall, 4 experiments	best	0.948	0.928	0.868	0.835	0.762	0.745
Methyl HT-SELEX, 2 experiments	median	0.933	0.907	0.816	0.797	0.692	0.696
Methyl HT-SELEX, 2 experiments	best	0.948	0.928	0.818	0.804	0.709	0.7
Non-Methyl HT-SELEX, 2 experiments	median	0.938	0.915	0.835	0.814	0.717	0.716
Non-Methyl HT-SELEX, 2 experiments	best	0.941	0.917	0.868	0.835	0.762	0.745

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.915	0.675	0.913	0.572
batch 2	0.676	0.407	0.715	0.494

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.1
HGNC	HGNC:6776
MGI	MGI:96909
EntrezGene (human)	GeneID:4094 (SSTAR profile)
EntrezGene (mouse)	GeneID:17132 (SSTAR profile)
UniProt ID (human)	MAF_HUMAN
UniProt ID (mouse)	MAF_MOUSE
UniProt AC (human)	O75444 (TFClass)
UniProt AC (mouse)	P54843 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	2
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	MAF.H14INVIVO.1.PSM.A.pcm
PWM	MAF.H14INVIVO.1.PSM.A.pwm
PFM	MAF.H14INVIVO.1.PSM.A.pfm
Threshold to P-value map	MAF.H14INVIVO.1.PSM.A.thr
Motif in other formats
JASPAR format	MAF.H14INVIVO.1.PSM.A_jaspar_format.txt
MEME format	MAF.H14INVIVO.1.PSM.A_meme_format.meme
Transfac format	MAF.H14INVIVO.1.PSM.A_transfac_format.txt
Homer format	MAF.H14INVIVO.1.PSM.A_homer_format_0.001.txt MAF.H14INVIVO.1.PSM.A_homer_format_0.0005.txt MAF.H14INVIVO.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	87.0	87.0	104.0	44.0
02	116.25	51.25	89.25	65.25
03	115.0	41.0	52.0	114.0
04	141.0	51.0	38.0	92.0
05	98.0	44.0	70.0	110.0
06	1.0	42.0	0.0	279.0
07	0.0	0.0	322.0	0.0
08	0.0	322.0	0.0	0.0
09	0.0	0.0	0.0	322.0
10	0.0	0.0	322.0	0.0
11	322.0	0.0	0.0	0.0
12	1.0	275.0	20.0	26.0
13	38.0	44.0	176.0	64.0
14	43.5	131.5	46.5	100.5
15	90.5	66.5	99.5	65.5

PFM

	A	C	G	T
01	0.27	0.27	0.323	0.137
02	0.361	0.159	0.277	0.203
03	0.357	0.127	0.161	0.354
04	0.438	0.158	0.118	0.286
05	0.304	0.137	0.217	0.342
06	0.003	0.13	0.0	0.866
07	0.0	0.0	1.0	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	0.0	1.0
10	0.0	0.0	1.0	0.0
11	1.0	0.0	0.0	0.0
12	0.003	0.854	0.062	0.081
13	0.118	0.137	0.547	0.199
14	0.135	0.408	0.144	0.312
15	0.281	0.207	0.309	0.203

PWM

	A	C	G	T
01	0.076	0.076	0.252	-0.59
02	0.362	-0.442	0.101	-0.206
03	0.351	-0.658	-0.427	0.343
04	0.553	-0.446	-0.731	0.131
05	0.194	-0.59	-0.137	0.307
06	-3.513	-0.635	-4.039	1.23
07	-4.039	-4.039	1.373	-4.039
08	-4.039	1.373	-4.039	-4.039
09	-4.039	-4.039	-4.039	1.373
10	-4.039	-4.039	1.373	-4.039
11	1.373	-4.039	-4.039	-4.039
12	-3.513	1.216	-1.341	-1.094
13	-0.731	-0.59	0.773	-0.225
14	-0.601	0.484	-0.536	0.218
15	0.115	-0.187	0.209	-0.202

Standard thresholds

P-value	Threshold
0.001	3.26946
0.0005	4.38966
0.0001	7.21666