KLF6.H14INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF6.H14INVIVO.0.P.B
Gene (human)	KLF6 (GeneCards)
Gene synonyms (human)	BCD1, COPEB, CPBP, ST12
Gene (mouse)	Klf6
Gene synonyms (mouse)	Copeb, Cpbp
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	nvvdGGGMGKKGvvbbvv
GC content	70.87%
Information content (bits; total / per base)	11.526 / 0.64
Data sources	ChIP-Seq
Aligned words	991
Previous names	KLF6.H12INVIVO.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.709	0.755	0.485	0.556	0.778	0.863	2.538	3.272	4.196	48.377

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.786	0.721	0.713	0.669	0.637	0.618
Overall, 2 experiments	best	0.82	0.747	0.768	0.706	0.686	0.653
Methyl HT-SELEX, 1 experiments	median	0.82	0.747	0.768	0.706	0.686	0.653
Methyl HT-SELEX, 1 experiments	best	0.82	0.747	0.768	0.706	0.686	0.653
Non-Methyl HT-SELEX, 1 experiments	median	0.752	0.695	0.659	0.631	0.587	0.583
Non-Methyl HT-SELEX, 1 experiments	best	0.752	0.695	0.659	0.631	0.587	0.583

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.6
HGNC	HGNC:2235
MGI	MGI:1346318
EntrezGene (human)	GeneID:1316 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	KLF6_HUMAN
UniProt ID (mouse)	KLF6_MOUSE
UniProt AC (human)	Q99612 (TFClass)
UniProt AC (mouse)	O08584 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	KLF6.H14INVIVO.0.P.B.pcm
PWM	KLF6.H14INVIVO.0.P.B.pwm
PFM	KLF6.H14INVIVO.0.P.B.pfm
Threshold to P-value map	KLF6.H14INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	KLF6.H14INVIVO.0.P.B_jaspar_format.txt
MEME format	KLF6.H14INVIVO.0.P.B_meme_format.meme
Transfac format	KLF6.H14INVIVO.0.P.B_transfac_format.txt
Homer format	KLF6.H14INVIVO.0.P.B_homer_format_0.001.txt KLF6.H14INVIVO.0.P.B_homer_format_0.0005.txt KLF6.H14INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	209.0	244.0	368.0	170.0
02	237.0	127.0	533.0	94.0
03	365.0	251.0	300.0	75.0
04	453.0	29.0	276.0	233.0
05	27.0	4.0	860.0	100.0
06	4.0	2.0	975.0	10.0
07	10.0	4.0	970.0	7.0
08	242.0	532.0	3.0	214.0
09	90.0	21.0	869.0	11.0
10	13.0	41.0	628.0	309.0
11	104.0	68.0	690.0	129.0
12	69.0	41.0	831.0	50.0
13	227.0	493.0	166.0	105.0
14	222.0	432.0	171.0	166.0
15	98.0	215.0	428.0	250.0
16	120.0	188.0	554.0	129.0
17	149.0	255.0	501.0	86.0
18	300.0	190.0	382.0	119.0

PFM

	A	C	G	T
01	0.211	0.246	0.371	0.172
02	0.239	0.128	0.538	0.095
03	0.368	0.253	0.303	0.076
04	0.457	0.029	0.279	0.235
05	0.027	0.004	0.868	0.101
06	0.004	0.002	0.984	0.01
07	0.01	0.004	0.979	0.007
08	0.244	0.537	0.003	0.216
09	0.091	0.021	0.877	0.011
10	0.013	0.041	0.634	0.312
11	0.105	0.069	0.696	0.13
12	0.07	0.041	0.839	0.05
13	0.229	0.497	0.168	0.106
14	0.224	0.436	0.173	0.168
15	0.099	0.217	0.432	0.252
16	0.121	0.19	0.559	0.13
17	0.15	0.257	0.506	0.087
18	0.303	0.192	0.385	0.12

PWM

	A	C	G	T
01	-0.169	-0.015	0.393	-0.373
02	-0.044	-0.662	0.762	-0.958
03	0.385	0.013	0.19	-1.179
04	0.6	-2.094	0.107	-0.061
05	-2.162	-3.775	1.24	-0.897
06	-3.775	-4.204	1.365	-3.058
07	-3.058	-3.775	1.36	-3.353
08	-0.023	0.761	-3.967	-0.145
09	-1.001	-2.396	1.25	-2.976
10	-2.83	-1.765	0.926	0.22
11	-0.859	-1.275	1.02	-0.646
12	-1.261	-1.765	1.205	-1.573
13	-0.087	0.685	-0.397	-0.849
14	-0.109	0.553	-0.368	-0.397
15	-0.917	-0.141	0.544	0.009
16	-0.718	-0.274	0.801	-0.646
17	-0.504	0.029	0.701	-1.045
18	0.19	-0.263	0.431	-0.726

Standard thresholds

P-value	Threshold
0.001	4.36801
0.0005	5.30956
0.0001	7.22291