| Motif | KLF12.H14INVIVO.0.P.C |
| Gene (human) | KLF12 (GeneCards) |
| Gene synonyms (human) | AP2REP |
| Gene (mouse) | Klf12 |
| Gene synonyms (mouse) | Ap2rep |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | C |
| Motif | KLF12.H14INVIVO.0.P.C |
| Gene (human) | KLF12 (GeneCards) |
| Gene synonyms (human) | AP2REP |
| Gene (mouse) | Klf12 |
| Gene synonyms (mouse) | Ap2rep |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | C |
| Motif length | 20 |
| Consensus | vdGGGCGKGGMvdRRvvbSR |
| GC content | 79.13% |
| Information content (bits; total / per base) | 16.853 / 0.843 |
| Data sources | ChIP-Seq |
| Aligned words | 907 |
| Previous names | KLF12.H12INVIVO.0.P.C |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (5) | 0.83 | 0.842 | 0.708 | 0.723 | 0.858 | 0.874 | 3.964 | 4.054 | 113.237 | 131.886 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.647 | 0.611 | 0.603 | 0.58 | 0.561 | 0.554 |
| best | 0.895 | 0.84 | 0.857 | 0.801 | 0.777 | 0.739 | |
| Methyl HT-SELEX, 1 experiments | median | 0.895 | 0.84 | 0.857 | 0.801 | 0.777 | 0.739 |
| best | 0.895 | 0.84 | 0.857 | 0.801 | 0.777 | 0.739 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.538 | 0.535 | 0.515 | 0.517 | 0.505 | 0.509 |
| best | 0.755 | 0.687 | 0.692 | 0.643 | 0.617 | 0.599 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.707 | 0.133 | 0.79 | 0.517 |
| batch 2 | 0.635 | 0.089 | 0.339 | 0.187 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Kr-like {2.3.1.2} (TFClass) |
| TFClass ID | TFClass: 2.3.1.2.12 |
| HGNC | HGNC:6346 |
| MGI | MGI:1333796 |
| EntrezGene (human) | GeneID:11278 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16597 (SSTAR profile) |
| UniProt ID (human) | KLF12_HUMAN |
| UniProt ID (mouse) | KLF12_MOUSE |
| UniProt AC (human) | Q9Y4X4 (TFClass) |
| UniProt AC (mouse) | O35738 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | KLF12.H14INVIVO.0.P.C.pcm |
| PWM | KLF12.H14INVIVO.0.P.C.pwm |
| PFM | KLF12.H14INVIVO.0.P.C.pfm |
| Threshold to P-value map | KLF12.H14INVIVO.0.P.C.thr |
| Motif in other formats | |
| JASPAR format | KLF12.H14INVIVO.0.P.C_jaspar_format.txt |
| MEME format | KLF12.H14INVIVO.0.P.C_meme_format.meme |
| Transfac format | KLF12.H14INVIVO.0.P.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 274.0 | 345.0 | 240.0 | 48.0 |
| 02 | 235.0 | 33.0 | 458.0 | 181.0 |
| 03 | 90.0 | 2.0 | 793.0 | 22.0 |
| 04 | 0.0 | 5.0 | 900.0 | 2.0 |
| 05 | 2.0 | 5.0 | 898.0 | 2.0 |
| 06 | 148.0 | 702.0 | 1.0 | 56.0 |
| 07 | 46.0 | 4.0 | 840.0 | 17.0 |
| 08 | 25.0 | 25.0 | 672.0 | 185.0 |
| 09 | 104.0 | 5.0 | 782.0 | 16.0 |
| 10 | 46.0 | 24.0 | 823.0 | 14.0 |
| 11 | 107.0 | 707.0 | 45.0 | 48.0 |
| 12 | 156.0 | 379.0 | 223.0 | 149.0 |
| 13 | 162.0 | 84.0 | 413.0 | 248.0 |
| 14 | 117.0 | 57.0 | 689.0 | 44.0 |
| 15 | 107.0 | 98.0 | 681.0 | 21.0 |
| 16 | 178.0 | 255.0 | 400.0 | 74.0 |
| 17 | 150.0 | 187.0 | 489.0 | 81.0 |
| 18 | 106.0 | 182.0 | 492.0 | 127.0 |
| 19 | 120.0 | 123.0 | 573.0 | 91.0 |
| 20 | 132.0 | 97.0 | 623.0 | 55.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.302 | 0.38 | 0.265 | 0.053 |
| 02 | 0.259 | 0.036 | 0.505 | 0.2 |
| 03 | 0.099 | 0.002 | 0.874 | 0.024 |
| 04 | 0.0 | 0.006 | 0.992 | 0.002 |
| 05 | 0.002 | 0.006 | 0.99 | 0.002 |
| 06 | 0.163 | 0.774 | 0.001 | 0.062 |
| 07 | 0.051 | 0.004 | 0.926 | 0.019 |
| 08 | 0.028 | 0.028 | 0.741 | 0.204 |
| 09 | 0.115 | 0.006 | 0.862 | 0.018 |
| 10 | 0.051 | 0.026 | 0.907 | 0.015 |
| 11 | 0.118 | 0.779 | 0.05 | 0.053 |
| 12 | 0.172 | 0.418 | 0.246 | 0.164 |
| 13 | 0.179 | 0.093 | 0.455 | 0.273 |
| 14 | 0.129 | 0.063 | 0.76 | 0.049 |
| 15 | 0.118 | 0.108 | 0.751 | 0.023 |
| 16 | 0.196 | 0.281 | 0.441 | 0.082 |
| 17 | 0.165 | 0.206 | 0.539 | 0.089 |
| 18 | 0.117 | 0.201 | 0.542 | 0.14 |
| 19 | 0.132 | 0.136 | 0.632 | 0.1 |
| 20 | 0.146 | 0.107 | 0.687 | 0.061 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.188 | 0.417 | 0.056 | -1.525 |
| 02 | 0.035 | -1.885 | 0.699 | -0.223 |
| 03 | -0.913 | -4.122 | 1.247 | -2.266 |
| 04 | -4.899 | -3.529 | 1.373 | -4.122 |
| 05 | -4.122 | -3.529 | 1.371 | -4.122 |
| 06 | -0.423 | 1.125 | -4.437 | -1.376 |
| 07 | -1.566 | -3.69 | 1.304 | -2.503 |
| 08 | -2.147 | -2.147 | 1.081 | -0.202 |
| 09 | -0.771 | -3.529 | 1.233 | -2.558 |
| 10 | -1.566 | -2.185 | 1.284 | -2.678 |
| 11 | -0.743 | 1.132 | -1.588 | -1.525 |
| 12 | -0.371 | 0.511 | -0.017 | -0.416 |
| 13 | -0.333 | -0.98 | 0.596 | 0.089 |
| 14 | -0.655 | -1.359 | 1.106 | -1.609 |
| 15 | -0.743 | -0.829 | 1.095 | -2.309 |
| 16 | -0.24 | 0.117 | 0.564 | -1.105 |
| 17 | -0.409 | -0.191 | 0.765 | -1.016 |
| 18 | -0.752 | -0.218 | 0.771 | -0.574 |
| 19 | -0.63 | -0.605 | 0.923 | -0.902 |
| 20 | -0.536 | -0.839 | 1.006 | -1.394 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.37936 |
| 0.0005 | 3.59456 |
| 0.0001 | 6.13746 |