| Motif | HXB5.H14RSNP.0.SM.D |
| Gene (human) | HOXB5 (GeneCards) |
| Gene synonyms (human) | HOX2A |
| Gene (mouse) | Hoxb5 |
| Gene synonyms (mouse) | Hox-2.1, Hoxb-5 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | HXB5.H14RSNP.0.SM.D |
| Gene (human) | HOXB5 (GeneCards) |
| Gene synonyms (human) | HOX2A |
| Gene (mouse) | Hoxb5 |
| Gene synonyms (mouse) | Hox-2.1, Hoxb-5 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 11 |
| Consensus | nvbTAATKRbn |
| GC content | 35.75% |
| Information content (bits; total / per base) | 10.496 / 0.954 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9369 |
| Previous names | HXB5.H12RSNP.0.SM.D |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.869 | 0.836 | 0.786 | 0.762 | 0.672 | 0.677 |
| best | 0.96 | 0.934 | 0.933 | 0.901 | 0.864 | 0.836 | |
| Methyl HT-SELEX, 2 experiments | median | 0.877 | 0.847 | 0.805 | 0.782 | 0.73 | 0.718 |
| best | 0.96 | 0.934 | 0.933 | 0.901 | 0.864 | 0.836 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.817 | 0.78 | 0.748 | 0.725 | 0.654 | 0.655 |
| best | 0.956 | 0.934 | 0.899 | 0.868 | 0.804 | 0.78 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX5 {3.1.1.5} (TFClass) |
| TFClass ID | TFClass: 3.1.1.5.2 |
| HGNC | HGNC:5116 |
| MGI | MGI:96186 |
| EntrezGene (human) | GeneID:3215 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15413 (SSTAR profile) |
| UniProt ID (human) | HXB5_HUMAN |
| UniProt ID (mouse) | HXB5_MOUSE |
| UniProt AC (human) | P09067 (TFClass) |
| UniProt AC (mouse) | P09079 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | HXB5.H14RSNP.0.SM.D.pcm |
| PWM | HXB5.H14RSNP.0.SM.D.pwm |
| PFM | HXB5.H14RSNP.0.SM.D.pfm |
| Threshold to P-value map | HXB5.H14RSNP.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | HXB5.H14RSNP.0.SM.D_jaspar_format.txt |
| MEME format | HXB5.H14RSNP.0.SM.D_meme_format.meme |
| Transfac format | HXB5.H14RSNP.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1907.75 | 3457.75 | 1944.75 | 2058.75 |
| 02 | 2427.0 | 2313.0 | 4050.0 | 579.0 |
| 03 | 316.0 | 3598.0 | 1269.0 | 4186.0 |
| 04 | 0.0 | 0.0 | 0.0 | 9369.0 |
| 05 | 9369.0 | 0.0 | 0.0 | 0.0 |
| 06 | 9369.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 69.0 | 0.0 | 9300.0 |
| 08 | 17.0 | 123.0 | 4609.0 | 4620.0 |
| 09 | 5756.0 | 141.0 | 3185.0 | 287.0 |
| 10 | 930.5 | 4019.5 | 2765.5 | 1653.5 |
| 11 | 1850.5 | 2659.5 | 2642.5 | 2216.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.204 | 0.369 | 0.208 | 0.22 |
| 02 | 0.259 | 0.247 | 0.432 | 0.062 |
| 03 | 0.034 | 0.384 | 0.135 | 0.447 |
| 04 | 0.0 | 0.0 | 0.0 | 1.0 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.007 | 0.0 | 0.993 |
| 08 | 0.002 | 0.013 | 0.492 | 0.493 |
| 09 | 0.614 | 0.015 | 0.34 | 0.031 |
| 10 | 0.099 | 0.429 | 0.295 | 0.176 |
| 11 | 0.198 | 0.284 | 0.282 | 0.237 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.205 | 0.389 | -0.186 | -0.129 |
| 02 | 0.036 | -0.013 | 0.547 | -1.395 |
| 03 | -1.997 | 0.429 | -0.612 | 0.58 |
| 04 | -6.933 | -6.933 | -6.933 | 1.386 |
| 05 | 1.386 | -6.933 | -6.933 | -6.933 |
| 06 | 1.386 | -6.933 | -6.933 | -6.933 |
| 07 | -6.933 | -3.493 | -6.933 | 1.378 |
| 08 | -4.8 | -2.929 | 0.676 | 0.679 |
| 09 | 0.899 | -2.795 | 0.307 | -2.092 |
| 10 | -0.922 | 0.54 | 0.166 | -0.348 |
| 11 | -0.235 | 0.127 | 0.121 | -0.055 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.53474 |
| 0.0005 | 6.09241 |
| 0.0001 | 7.81368 |