| Motif | HXB2.H14CORE.0.SM.B |
| Gene (human) | HOXB2 (GeneCards) |
| Gene synonyms (human) | HOX2H |
| Gene (mouse) | Hoxb2 |
| Gene synonyms (mouse) | Hox-2.8 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | HXB2.H14CORE.0.SM.B |
| Gene (human) | HOXB2 (GeneCards) |
| Gene synonyms (human) | HOX2H |
| Gene (mouse) | Hoxb2 |
| Gene synonyms (mouse) | Hox-2.8 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 12 |
| Consensus | nvvYTAATKRbn |
| GC content | 38.62% |
| Information content (bits; total / per base) | 11.188 / 0.932 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8768 |
| Previous names | HXB2.H12CORE.0.SM.B |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.986 | 0.978 | 0.976 | 0.962 | 0.949 | 0.93 |
| best | 0.992 | 0.987 | 0.983 | 0.974 | 0.97 | 0.956 | |
| Methyl HT-SELEX, 1 experiments | median | 0.99 | 0.984 | 0.983 | 0.973 | 0.97 | 0.956 |
| best | 0.99 | 0.984 | 0.983 | 0.973 | 0.97 | 0.956 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.982 | 0.972 | 0.97 | 0.952 | 0.948 | 0.926 |
| best | 0.992 | 0.987 | 0.982 | 0.974 | 0.949 | 0.935 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX2 {3.1.1.2} (TFClass) |
| TFClass ID | TFClass: 3.1.1.2.2 |
| HGNC | HGNC:5113 |
| MGI | MGI:96183 |
| EntrezGene (human) | GeneID:3212 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:103889 (SSTAR profile) |
| UniProt ID (human) | HXB2_HUMAN |
| UniProt ID (mouse) | HXB2_MOUSE |
| UniProt AC (human) | P14652 (TFClass) |
| UniProt AC (mouse) | P0C1T1 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | HXB2.H14CORE.0.SM.B.pcm |
| PWM | HXB2.H14CORE.0.SM.B.pwm |
| PFM | HXB2.H14CORE.0.SM.B.pfm |
| Threshold to P-value map | HXB2.H14CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | HXB2.H14CORE.0.SM.B_jaspar_format.txt |
| MEME format | HXB2.H14CORE.0.SM.B_meme_format.meme |
| Transfac format | HXB2.H14CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2192.0 | 2212.0 | 2387.0 | 1977.0 |
| 02 | 1478.25 | 3845.25 | 1973.25 | 1471.25 |
| 03 | 2175.0 | 2301.0 | 3923.0 | 369.0 |
| 04 | 92.0 | 5010.0 | 810.0 | 2856.0 |
| 05 | 0.0 | 0.0 | 0.0 | 8768.0 |
| 06 | 8768.0 | 0.0 | 0.0 | 0.0 |
| 07 | 8768.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 1.0 | 1.0 | 8766.0 |
| 09 | 3.0 | 181.0 | 4089.0 | 4495.0 |
| 10 | 6547.0 | 140.0 | 1893.0 | 188.0 |
| 11 | 738.25 | 4186.25 | 2455.25 | 1388.25 |
| 12 | 1621.0 | 2570.0 | 2657.0 | 1920.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.25 | 0.252 | 0.272 | 0.225 |
| 02 | 0.169 | 0.439 | 0.225 | 0.168 |
| 03 | 0.248 | 0.262 | 0.447 | 0.042 |
| 04 | 0.01 | 0.571 | 0.092 | 0.326 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 1.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 0.0 | 1.0 |
| 09 | 0.0 | 0.021 | 0.466 | 0.513 |
| 10 | 0.747 | 0.016 | 0.216 | 0.021 |
| 11 | 0.084 | 0.477 | 0.28 | 0.158 |
| 12 | 0.185 | 0.293 | 0.303 | 0.219 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.0 | 0.009 | 0.085 | -0.103 |
| 02 | -0.393 | 0.562 | -0.105 | -0.398 |
| 03 | -0.008 | 0.048 | 0.582 | -1.777 |
| 04 | -3.147 | 0.826 | -0.994 | 0.264 |
| 05 | -6.874 | -6.874 | -6.874 | 1.386 |
| 06 | 1.386 | -6.874 | -6.874 | -6.874 |
| 07 | 1.386 | -6.874 | -6.874 | -6.874 |
| 08 | -6.874 | -6.509 | -6.509 | 1.385 |
| 09 | -6.032 | -2.483 | 0.623 | 0.718 |
| 10 | 1.094 | -2.736 | -0.146 | -2.445 |
| 11 | -1.086 | 0.646 | 0.113 | -0.456 |
| 12 | -0.301 | 0.159 | 0.192 | -0.132 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.06156 |
| 0.0005 | 5.60036 |
| 0.0001 | 7.83836 |