HSFY1.H14INVIVO.0.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HSFY1.H14INVIVO.0.S.D
Gene (human)	HSFY1 (GeneCards)
Gene synonyms (human)	HSFY2, HSF2L, HSFY, HSF2L, HSFY
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	ndCGTTCGAAhn
GC content	42.1%
Information content (bits; total / per base)	13.451 / 1.121
Data sources	HT-SELEX
Aligned words	8508
Previous names	HSFY1.H12INVIVO.0.S.D

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.923	0.907	0.781	0.786	0.64	0.673
Overall, 6 experiments	best	0.992	0.987	0.973	0.965	0.823	0.838
Methyl HT-SELEX, 2 experiments	median	0.806	0.774	0.661	0.661	0.572	0.593
Methyl HT-SELEX, 2 experiments	best	0.86	0.835	0.682	0.693	0.573	0.607
Non-Methyl HT-SELEX, 4 experiments	median	0.989	0.983	0.91	0.905	0.749	0.77
Non-Methyl HT-SELEX, 4 experiments	best	0.992	0.987	0.973	0.965	0.823	0.838

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Heat shock factors {3.4} (TFClass)
TF family	HSF {3.4.1} (TFClass)
TF subfamily	{3.4.1.0} (TFClass)
TFClass ID	TFClass: 3.4.1.0.8
HGNC	HGNC:18568 HGNC:23950
MGI
EntrezGene (human)	GeneID:159119 (SSTAR profile) GeneID:86614 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	HSFY1_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96LI6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	HSFY1.H14INVIVO.0.S.D.pcm
PWM	HSFY1.H14INVIVO.0.S.D.pwm
PFM	HSFY1.H14INVIVO.0.S.D.pfm
Threshold to P-value map	HSFY1.H14INVIVO.0.S.D.thr
Motif in other formats
JASPAR format	HSFY1.H14INVIVO.0.S.D_jaspar_format.txt
MEME format	HSFY1.H14INVIVO.0.S.D_meme_format.meme
Transfac format	HSFY1.H14INVIVO.0.S.D_transfac_format.txt
Homer format	HSFY1.H14INVIVO.0.S.D_homer_format_0.001.txt HSFY1.H14INVIVO.0.S.D_homer_format_0.0005.txt HSFY1.H14INVIVO.0.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2821.75	1754.75	1456.75	2474.75
02	3560.5	1022.5	2556.5	1368.5
03	383.0	7081.0	577.0	467.0
04	3264.0	11.0	5233.0	0.0
05	0.0	0.0	1.0	8507.0
06	0.0	0.0	0.0	8508.0
07	0.0	8508.0	0.0	0.0
08	0.0	87.0	8090.0	331.0
09	8448.0	1.0	15.0	44.0
10	7393.0	135.0	73.0	907.0
11	3334.25	1332.25	904.25	2937.25
12	2317.75	2452.75	1693.75	2043.75

PFM

	A	C	G	T
01	0.332	0.206	0.171	0.291
02	0.418	0.12	0.3	0.161
03	0.045	0.832	0.068	0.055
04	0.384	0.001	0.615	0.0
05	0.0	0.0	0.0	1.0
06	0.0	0.0	0.0	1.0
07	0.0	1.0	0.0	0.0
08	0.0	0.01	0.951	0.039
09	0.993	0.0	0.002	0.005
10	0.869	0.016	0.009	0.107
11	0.392	0.157	0.106	0.345
12	0.272	0.288	0.199	0.24

PWM

	A	C	G	T
01	0.282	-0.192	-0.378	0.151
02	0.515	-0.731	0.184	-0.44
03	-1.71	1.202	-1.302	-1.512
04	0.428	-5.079	0.9	-6.847
05	-6.847	-6.847	-6.481	1.385
06	-6.847	-6.847	-6.847	1.385
07	-6.847	1.385	-6.847	-6.847
08	-6.847	-3.172	1.335	-1.855
09	1.378	-6.481	-4.815	-3.829
10	1.245	-2.742	-3.343	-0.851
11	0.449	-0.467	-0.854	0.322
12	0.086	0.142	-0.227	-0.04

Standard thresholds

P-value	Threshold
0.001	2.18271
0.0005	3.79261
0.0001	7.126015