| Motif | HME2.H14INVIVO.0.SM.D |
| Gene (human) | EN2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | En2 |
| Gene synonyms (mouse) | En-2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | HME2.H14INVIVO.0.SM.D |
| Gene (human) | EN2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | En2 |
| Gene synonyms (mouse) | En-2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 10 |
| Consensus | nbRATTAvbn |
| GC content | 35.46% |
| Information content (bits; total / per base) | 8.292 / 0.829 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9153 |
| Previous names | HME2.H12INVIVO.0.SM.D |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.828 | 0.79 | 0.716 | 0.692 | 0.632 | 0.627 |
| best | 0.991 | 0.986 | 0.98 | 0.971 | 0.952 | 0.936 | |
| Methyl HT-SELEX, 2 experiments | median | 0.91 | 0.884 | 0.852 | 0.833 | 0.792 | 0.781 |
| best | 0.991 | 0.986 | 0.98 | 0.971 | 0.95 | 0.935 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.825 | 0.79 | 0.706 | 0.688 | 0.629 | 0.624 |
| best | 0.99 | 0.984 | 0.98 | 0.969 | 0.952 | 0.936 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | EN {3.1.2.7} (TFClass) |
| TFClass ID | TFClass: 3.1.2.7.2 |
| HGNC | HGNC:3343 |
| MGI | MGI:95390 |
| EntrezGene (human) | GeneID:2020 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:13799 (SSTAR profile) |
| UniProt ID (human) | HME2_HUMAN |
| UniProt ID (mouse) | HME2_MOUSE |
| UniProt AC (human) | P19622 (TFClass) |
| UniProt AC (mouse) | P09066 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | HME2.H14INVIVO.0.SM.D.pcm |
| PWM | HME2.H14INVIVO.0.SM.D.pwm |
| PFM | HME2.H14INVIVO.0.SM.D.pfm |
| Threshold to P-value map | HME2.H14INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | HME2.H14INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | HME2.H14INVIVO.0.SM.D_meme_format.meme |
| Transfac format | HME2.H14INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2189.75 | 2668.75 | 2118.75 | 2175.75 |
| 02 | 627.75 | 4276.75 | 790.75 | 3457.75 |
| 03 | 6380.0 | 1258.0 | 1287.0 | 228.0 |
| 04 | 8931.0 | 142.0 | 80.0 | 0.0 |
| 05 | 0.0 | 9.0 | 1.0 | 9143.0 |
| 06 | 0.0 | 689.0 | 0.0 | 8464.0 |
| 07 | 8162.0 | 364.0 | 578.0 | 49.0 |
| 08 | 1658.0 | 2550.0 | 4305.0 | 640.0 |
| 09 | 996.75 | 3018.75 | 3140.75 | 1996.75 |
| 10 | 2154.5 | 2241.5 | 2939.5 | 1817.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.239 | 0.292 | 0.231 | 0.238 |
| 02 | 0.069 | 0.467 | 0.086 | 0.378 |
| 03 | 0.697 | 0.137 | 0.141 | 0.025 |
| 04 | 0.976 | 0.016 | 0.009 | 0.0 |
| 05 | 0.0 | 0.001 | 0.0 | 0.999 |
| 06 | 0.0 | 0.075 | 0.0 | 0.925 |
| 07 | 0.892 | 0.04 | 0.063 | 0.005 |
| 08 | 0.181 | 0.279 | 0.47 | 0.07 |
| 09 | 0.109 | 0.33 | 0.343 | 0.218 |
| 10 | 0.235 | 0.245 | 0.321 | 0.199 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.044 | 0.154 | -0.077 | -0.05 |
| 02 | -1.291 | 0.625 | -1.061 | 0.412 |
| 03 | 1.025 | -0.597 | -0.575 | -2.297 |
| 04 | 1.361 | -2.765 | -3.326 | -6.912 |
| 05 | -6.912 | -5.313 | -6.549 | 1.384 |
| 06 | -6.912 | -1.198 | -6.912 | 1.307 |
| 07 | 1.271 | -1.833 | -1.373 | -3.799 |
| 08 | -0.322 | 0.108 | 0.632 | -1.272 |
| 09 | -0.83 | 0.277 | 0.316 | -0.136 |
| 10 | -0.06 | -0.021 | 0.25 | -0.23 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.322615 |
| 0.0005 | 5.978135 |
| 0.0001 | 7.332785 |