MotifHME1.H14CORE.0.PSM.A
Gene (human)EN1
(GeneCards)
Gene synonyms (human)
Gene (mouse)En1
Gene synonyms (mouse)En-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length13
ConsensusnnvTAATTARbnn
GC content35.93%
Information content (bits; total / per base)11.85 / 0.912
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words2375
Previous namesHME1.H12CORE.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (2) 0.733 0.733 0.624 0.624 0.713 0.713 2.068 2.068 12.032 12.032

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.928 0.901 0.804 0.787 0.672 0.683
best 0.958 0.93 0.938 0.904 0.886 0.848
Methyl HT-SELEX, 1 experiments median 0.958 0.93 0.938 0.904 0.88 0.848
best 0.958 0.93 0.938 0.904 0.88 0.848
Non-Methyl HT-SELEX, 5 experiments median 0.923 0.893 0.797 0.78 0.669 0.679
best 0.95 0.917 0.929 0.891 0.886 0.847
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyEN {3.1.2.7} (TFClass)
TFClass IDTFClass: 3.1.2.7.1
HGNCHGNC:3342
MGIMGI:95389
EntrezGene (human)GeneID:2019
(SSTAR profile)
EntrezGene (mouse)GeneID:13798
(SSTAR profile)
UniProt ID (human)HME1_HUMAN
UniProt ID (mouse)HME1_MOUSE
UniProt AC (human)Q05925
(TFClass)
UniProt AC (mouse)P09065
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01614.25469.25737.25554.25
02673.5499.5817.5384.5
03324.0965.0875.0211.0
047.0805.06.01557.0
052285.064.026.00.0
062375.00.00.00.0
070.00.00.02375.0
080.00.00.02375.0
092354.017.02.02.0
10742.0151.01364.0118.0
11101.0808.0729.0737.0
12479.5588.5903.5403.5
13621.75639.75624.75488.75
PFM
ACGT
010.2590.1980.310.233
020.2840.210.3440.162
030.1360.4060.3680.089
040.0030.3390.0030.656
050.9620.0270.0110.0
061.00.00.00.0
070.00.00.01.0
080.00.00.01.0
090.9910.0070.0010.001
100.3120.0640.5740.05
110.0430.340.3070.31
120.2020.2480.380.17
130.2620.2690.2630.206
PWM
ACGT
010.034-0.2340.216-0.069
020.126-0.1720.319-0.433
03-0.6030.4840.387-1.029
04-4.1990.304-4.3170.962
051.345-2.201-3.06-5.725
061.384-5.725-5.725-5.725
07-5.725-5.725-5.7251.384
08-5.725-5.725-5.7251.384
091.375-3.448-5.018-5.018
100.222-1.360.83-1.603
11-1.7560.3070.2050.215
12-0.213-0.0090.419-0.385
130.0460.0740.051-0.194
Standard thresholds
P-value Threshold
0.001 3.220165
0.0005 4.818915
0.0001 7.899775