MotifHLF.H14RSNP.1.SM.B
Gene (human)HLF
(GeneCards)
Gene synonyms (human)
Gene (mouse)Hlf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusnbGTTACGTAAbvn
GC content42.15%
Information content (bits; total / per base)17.138 / 1.224
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words512
Previous namesHLF.H12RSNP.1.SM.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.787 0.793 0.761 0.768 0.924 0.931 3.604 3.668 708.367 777.301
Mouse 3 (16) 0.622 0.639 0.543 0.575 0.818 0.849 2.581 2.747 179.607 205.018

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.846 0.839 0.695 0.703 0.601 0.622
best 0.992 0.985 0.987 0.979 0.975 0.964
Methyl HT-SELEX, 1 experiments median 0.992 0.985 0.987 0.979 0.975 0.964
best 0.992 0.985 0.987 0.979 0.975 0.964
Non-Methyl HT-SELEX, 5 experiments median 0.754 0.747 0.632 0.638 0.57 0.583
best 0.99 0.984 0.985 0.975 0.971 0.957

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.845 0.82 0.112 0.134

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.947 0.365 0.951 0.588
batch 2 0.887 0.696 0.829 0.591
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyC/EBP-related {1.1.8} (TFClass)
TF subfamilyPAR {1.1.8.2} (TFClass)
TFClass IDTFClass: 1.1.8.2.2
HGNCHGNC:4977
MGIMGI:96108
EntrezGene (human)GeneID:3131
(SSTAR profile)
EntrezGene (mouse)GeneID:217082
(SSTAR profile)
UniProt ID (human)HLF_HUMAN
UniProt ID (mouse)HLF_MOUSE
UniProt AC (human)Q16534
(TFClass)
UniProt AC (mouse)Q8BW74
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 3 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01132.590.5176.5112.5
0264.0146.0177.0125.0
0324.026.0462.00.0
040.00.00.0512.0
050.00.00.0512.0
06512.00.00.00.0
070.0401.00.0111.0
080.00.0512.00.0
090.016.00.0496.0
10509.03.00.00.0
11512.00.00.00.0
1212.0157.0183.0160.0
1386.2593.25264.2568.25
1497.25138.25175.25101.25
PFM
ACGT
010.2590.1770.3450.22
020.1250.2850.3460.244
030.0470.0510.9020.0
040.00.00.01.0
050.00.00.01.0
061.00.00.00.0
070.00.7830.00.217
080.00.01.00.0
090.00.0310.00.969
100.9940.0060.00.0
111.00.00.00.0
120.0230.3070.3570.313
130.1680.1820.5160.133
140.190.270.3420.198
PWM
ACGT
010.034-0.3420.318-0.127
02-0.6810.130.321-0.023
03-1.623-1.5481.275-4.42
04-4.42-4.42-4.421.377
05-4.42-4.42-4.421.377
061.377-4.42-4.42-4.42
07-4.421.134-4.42-0.141
08-4.42-4.421.377-4.42
09-4.42-1.999-4.421.346
101.371-3.347-4.42-4.42
111.377-4.42-4.42-4.42
12-2.2570.2020.3540.221
13-0.389-0.3120.719-0.618
14-0.2710.0760.311-0.231
Standard thresholds
P-value Threshold
0.001 0.52062
0.0005 1.975965
0.0001 5.57913