HIF1A.H14RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HIF1A.H14RSNP.0.P.B
Gene (human)	HIF1A (GeneCards)
Gene synonyms (human)	BHLHE78, MOP1, PASD8
Gene (mouse)	Hif1a
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	8
Consensus	vKACGTGM
GC content	60.2%
Information content (bits; total / per base)	9.665 / 1.208
Data sources	ChIP-Seq
Aligned words	999
Previous names	HIF1A.H12RSNP.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	24 (137)	0.834	0.924	0.764	0.89	0.8	0.909	2.666	3.516	169.0	425.432
Mouse	4 (25)	0.839	0.882	0.743	0.801	0.828	0.881	2.771	3.377	176.796	291.292

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	18.972	11.551	0.291	0.184

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	PAS {1.2.5} (TFClass)
TF subfamily	PAS-AHR {1.2.5.1} (TFClass)
TFClass ID	TFClass: 1.2.5.1.5
HGNC	HGNC:4910
MGI	MGI:106918
EntrezGene (human)	GeneID:3091 (SSTAR profile)
EntrezGene (mouse)	GeneID:15251 (SSTAR profile)
UniProt ID (human)	HIF1A_HUMAN
UniProt ID (mouse)	HIF1A_MOUSE
UniProt AC (human)	Q16665 (TFClass)
UniProt AC (mouse)	Q61221 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	24 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	HIF1A.H14RSNP.0.P.B.pcm
PWM	HIF1A.H14RSNP.0.P.B.pwm
PFM	HIF1A.H14RSNP.0.P.B.pfm
Threshold to P-value map	HIF1A.H14RSNP.0.P.B.thr
Motif in other formats
JASPAR format	HIF1A.H14RSNP.0.P.B_jaspar_format.txt
MEME format	HIF1A.H14RSNP.0.P.B_meme_format.meme
Transfac format	HIF1A.H14RSNP.0.P.B_transfac_format.txt
Homer format	HIF1A.H14RSNP.0.P.B_homer_format_0.001.txt HIF1A.H14RSNP.0.P.B_homer_format_0.0005.txt HIF1A.H14RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	161.0	240.0	503.0	95.0
02	115.0	11.0	390.0	483.0
03	808.0	4.0	176.0	11.0
04	61.0	916.0	7.0	15.0
05	28.0	2.0	967.0	2.0
06	1.0	3.0	0.0	995.0
07	1.0	0.0	998.0	0.0
08	320.0	534.0	60.0	85.0

PFM

	A	C	G	T
01	0.161	0.24	0.504	0.095
02	0.115	0.011	0.39	0.483
03	0.809	0.004	0.176	0.011
04	0.061	0.917	0.007	0.015
05	0.028	0.002	0.968	0.002
06	0.001	0.003	0.0	0.996
07	0.001	0.0	0.999	0.0
08	0.32	0.535	0.06	0.085

PWM

	A	C	G	T
01	-0.435	-0.04	0.697	-0.955
02	-0.768	-2.984	0.443	0.656
03	1.169	-3.782	-0.347	-2.984
04	-1.389	1.295	-3.361	-2.71
05	-2.135	-4.212	1.349	-4.212
06	-4.524	-3.974	-4.981	1.377
07	-4.524	-4.981	1.38	-4.981
08	0.246	0.756	-1.405	-1.065

Standard thresholds

P-value	Threshold
0.001	5.004325
0.0005	6.004635
0.0001	7.505245