HES2.H14INVITRO.0.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HES2.H14INVITRO.0.S.C
Gene (human)	HES2 (GeneCards)
Gene synonyms (human)	BHLHB40
Gene (mouse)	Hes2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	14
Consensus	nnhGGCACGTGbbn
GC content	64.94%
Information content (bits; total / per base)	14.951 / 1.068
Data sources	HT-SELEX
Aligned words	9732
Previous names	HES2.H12INVITRO.0.S.C

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.998	0.997	0.996	0.995	0.986	0.982
Non-Methyl HT-SELEX, 1 experiments	best	0.998	0.997	0.996	0.995	0.986	0.982

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.892	0.806	0.77	0.638

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Hairy-related {1.2.4} (TFClass)
TF subfamily	HAIRY {1.2.4.1} (TFClass)
TFClass ID	TFClass: 1.2.4.1.2
HGNC	HGNC:16005
MGI	MGI:1098624
EntrezGene (human)	GeneID:54626 (SSTAR profile)
EntrezGene (mouse)	GeneID:15206 (SSTAR profile)
UniProt ID (human)	HES2_HUMAN
UniProt ID (mouse)	HES2_MOUSE
UniProt AC (human)	Q9Y543 (TFClass)
UniProt AC (mouse)	O54792 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	HES2.H14INVITRO.0.S.C.pcm
PWM	HES2.H14INVITRO.0.S.C.pwm
PFM	HES2.H14INVITRO.0.S.C.pfm
Threshold to P-value map	HES2.H14INVITRO.0.S.C.thr
Motif in other formats
JASPAR format	HES2.H14INVITRO.0.S.C_jaspar_format.txt
MEME format	HES2.H14INVITRO.0.S.C_meme_format.meme
Transfac format	HES2.H14INVITRO.0.S.C_transfac_format.txt
Homer format	HES2.H14INVITRO.0.S.C_homer_format_0.001.txt HES2.H14INVITRO.0.S.C_homer_format_0.0005.txt HES2.H14INVITRO.0.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2222.5	2652.5	2458.5	2398.5
02	2753.0	1444.0	3245.0	2290.0
03	1987.0	1756.0	1217.0	4772.0
04	352.0	193.0	9048.0	139.0
05	709.0	307.0	8566.0	150.0
06	9.0	9723.0	0.0	0.0
07	9706.0	0.0	23.0	3.0
08	0.0	9732.0	0.0	0.0
09	9.0	0.0	9722.0	1.0
10	38.0	901.0	13.0	8780.0
11	44.0	17.0	9596.0	75.0
12	704.0	4650.0	1210.0	3168.0
13	1217.5	4660.5	2070.5	1783.5
14	2253.0	2478.0	2796.0	2205.0

PFM

	A	C	G	T
01	0.228	0.273	0.253	0.246
02	0.283	0.148	0.333	0.235
03	0.204	0.18	0.125	0.49
04	0.036	0.02	0.93	0.014
05	0.073	0.032	0.88	0.015
06	0.001	0.999	0.0	0.0
07	0.997	0.0	0.002	0.0
08	0.0	1.0	0.0	0.0
09	0.001	0.0	0.999	0.0
10	0.004	0.093	0.001	0.902
11	0.005	0.002	0.986	0.008
12	0.072	0.478	0.124	0.326
13	0.125	0.479	0.213	0.183
14	0.232	0.255	0.287	0.227

PWM

	A	C	G	T
01	-0.09	0.086	0.01	-0.014
02	0.123	-0.521	0.288	-0.061
03	-0.202	-0.326	-0.692	0.673
04	-1.928	-2.523	1.313	-2.847
05	-1.231	-2.064	1.258	-2.772
06	-5.373	1.385	-6.967	-6.967
07	1.383	-6.967	-4.567	-6.131
08	-6.967	1.386	-6.967	-6.967
09	-5.373	-6.967	1.385	-6.605
10	-4.102	-0.992	-5.07	1.283
11	-3.963	-4.838	1.372	-3.45
12	-1.238	0.647	-0.698	0.264
13	-0.691	0.65	-0.161	-0.31
14	-0.077	0.018	0.139	-0.098

Standard thresholds

P-value	Threshold
0.001	1.21716
0.0005	2.85671
0.0001	6.28371