GRHL2.H14RSNP.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GRHL2.H14RSNP.1.P.B
Gene (human)	GRHL2 (GeneCards)
Gene synonyms (human)	BOM, TFCP2L3
Gene (mouse)	Grhl2
Gene synonyms (mouse)	Bom, Tcfcp2l3
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	nvRRChGGTTh
GC content	47.98%
Information content (bits; total / per base)	10.651 / 0.968
Data sources	ChIP-Seq
Aligned words	998
Previous names	GRHL2.H12RSNP.1.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	23 (153)	0.868	0.924	0.77	0.846	0.812	0.883	2.632	3.148	420.444	537.051
Mouse	4 (28)	0.849	0.886	0.752	0.82	0.786	0.834	2.629	3.028	301.546	439.051

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	9.563	10.126	0.344	0.32

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	Grainyhead-related {6.7.1} (TFClass)
TF subfamily	GRH-like {6.7.1.1} (TFClass)
TFClass ID	TFClass: 6.7.1.1.2
HGNC	HGNC:2799
MGI	MGI:2182543
EntrezGene (human)	GeneID:79977 (SSTAR profile)
EntrezGene (mouse)	GeneID:252973 (SSTAR profile)
UniProt ID (human)	GRHL2_HUMAN
UniProt ID (mouse)	GRHL2_MOUSE
UniProt AC (human)	Q6ISB3 (TFClass)
UniProt AC (mouse)	Q8K5C0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	23 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	GRHL2.H14RSNP.1.P.B.pcm
PWM	GRHL2.H14RSNP.1.P.B.pwm
PFM	GRHL2.H14RSNP.1.P.B.pfm
Threshold to P-value map	GRHL2.H14RSNP.1.P.B.thr
Motif in other formats
JASPAR format	GRHL2.H14RSNP.1.P.B_jaspar_format.txt
MEME format	GRHL2.H14RSNP.1.P.B_meme_format.meme
Transfac format	GRHL2.H14RSNP.1.P.B_transfac_format.txt
Homer format	GRHL2.H14RSNP.1.P.B_homer_format_0.001.txt GRHL2.H14RSNP.1.P.B_homer_format_0.0005.txt GRHL2.H14RSNP.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	371.0	371.0	136.0	120.0
02	452.0	128.0	338.0	80.0
03	712.0	22.0	235.0	29.0
04	741.0	7.0	199.0	51.0
05	4.0	990.0	4.0	0.0
06	409.0	211.0	31.0	347.0
07	63.0	7.0	928.0	0.0
08	4.0	7.0	986.0	1.0
09	53.0	88.0	5.0	852.0
10	32.0	185.0	8.0	773.0
11	108.0	299.0	82.0	509.0

PFM

	A	C	G	T
01	0.372	0.372	0.136	0.12
02	0.453	0.128	0.339	0.08
03	0.713	0.022	0.235	0.029
04	0.742	0.007	0.199	0.051
05	0.004	0.992	0.004	0.0
06	0.41	0.211	0.031	0.348
07	0.063	0.007	0.93	0.0
08	0.004	0.007	0.988	0.001
09	0.053	0.088	0.005	0.854
10	0.032	0.185	0.008	0.775
11	0.108	0.3	0.082	0.51

PWM

	A	C	G	T
01	0.394	0.394	-0.601	-0.725
02	0.591	-0.661	0.302	-1.123
03	1.044	-2.36	-0.059	-2.101
04	1.084	-3.36	-0.224	-1.561
05	-3.781	1.373	-3.781	-4.98
06	0.492	-0.166	-2.038	0.328
07	-1.356	-3.36	1.309	-4.98
08	-3.781	-3.36	1.369	-4.523
09	-1.524	-1.03	-3.62	1.223
10	-2.008	-0.297	-3.252	1.126
11	-0.828	0.18	-1.099	0.709

Standard thresholds

P-value	Threshold
0.001	4.611945
0.0005	5.56048
0.0001	7.46358