GRHL2.H14INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GRHL2.H14INVIVO.0.P.B
Gene (human)	GRHL2 (GeneCards)
Gene synonyms (human)	BOM, TFCP2L3
Gene (mouse)	Grhl2
Gene synonyms (mouse)	Bom, Tcfcp2l3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	CYdGTTYddChRG
GC content	56.53%
Information content (bits; total / per base)	10.943 / 0.842
Data sources	ChIP-Seq
Aligned words	985
Previous names	GRHL2.H12INVIVO.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	23 (153)	0.938	0.968	0.887	0.95	0.893	0.927	3.193	3.617	590.481	679.201
Mouse	4 (28)	0.891	0.937	0.838	0.874	0.837	0.888	2.97	3.255	343.843	634.387

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	6.483	7.328	0.349	0.264

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	Grainyhead-related {6.7.1} (TFClass)
TF subfamily	GRH-like {6.7.1.1} (TFClass)
TFClass ID	TFClass: 6.7.1.1.2
HGNC	HGNC:2799
MGI	MGI:2182543
EntrezGene (human)	GeneID:79977 (SSTAR profile)
EntrezGene (mouse)	GeneID:252973 (SSTAR profile)
UniProt ID (human)	GRHL2_HUMAN
UniProt ID (mouse)	GRHL2_MOUSE
UniProt AC (human)	Q6ISB3 (TFClass)
UniProt AC (mouse)	Q8K5C0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	23 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	GRHL2.H14INVIVO.0.P.B.pcm
PWM	GRHL2.H14INVIVO.0.P.B.pwm
PFM	GRHL2.H14INVIVO.0.P.B.pfm
Threshold to P-value map	GRHL2.H14INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	GRHL2.H14INVIVO.0.P.B_jaspar_format.txt
MEME format	GRHL2.H14INVIVO.0.P.B_meme_format.meme
Transfac format	GRHL2.H14INVIVO.0.P.B_transfac_format.txt
Homer format	GRHL2.H14INVIVO.0.P.B_homer_format_0.001.txt GRHL2.H14INVIVO.0.P.B_homer_format_0.0005.txt GRHL2.H14INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2.0	954.0	25.0	4.0
02	163.0	551.0	17.0	254.0
03	231.0	18.0	430.0	306.0
04	2.0	9.0	968.0	6.0
05	24.0	126.0	1.0	834.0
06	32.0	212.0	3.0	738.0
07	67.0	233.0	114.0	571.0
08	119.0	96.0	368.0	402.0
09	290.0	74.0	312.0	309.0
10	7.0	914.0	22.0	42.0
11	267.0	430.0	27.0	261.0
12	465.0	12.0	370.0	138.0
13	21.0	220.0	733.0	11.0

PFM

	A	C	G	T
01	0.002	0.969	0.025	0.004
02	0.165	0.559	0.017	0.258
03	0.235	0.018	0.437	0.311
04	0.002	0.009	0.983	0.006
05	0.024	0.128	0.001	0.847
06	0.032	0.215	0.003	0.749
07	0.068	0.237	0.116	0.58
08	0.121	0.097	0.374	0.408
09	0.294	0.075	0.317	0.314
10	0.007	0.928	0.022	0.043
11	0.271	0.437	0.027	0.265
12	0.472	0.012	0.376	0.14
13	0.021	0.223	0.744	0.011

PWM

	A	C	G	T
01	-4.199	1.349	-2.228	-3.769
02	-0.409	0.802	-2.584	0.031
03	-0.063	-2.532	0.554	0.216
04	-4.199	-3.141	1.364	-3.469
05	-2.266	-0.663	-4.512	1.215
06	-1.995	-0.149	-3.961	1.093
07	-1.283	-0.055	-0.762	0.837
08	-0.72	-0.931	0.399	0.487
09	0.162	-1.186	0.235	0.226
10	-3.347	1.306	-2.347	-1.735
11	0.08	0.554	-2.156	0.058
12	0.632	-2.894	0.405	-0.574
13	-2.39	-0.112	1.086	-2.97

Standard thresholds

P-value	Threshold
0.001	4.48491
0.0005	5.44616
0.0001	7.398155