| Motif | GRHL1.H14RSNP.0.PSM.A |
| Gene (human) | GRHL1 (GeneCards) |
| Gene synonyms (human) | LBP32, MGR, TFCP2L2 |
| Gene (mouse) | Grhl1 |
| Gene synonyms (mouse) | Mgr, Tcfcp2l2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | GRHL1.H14RSNP.0.PSM.A |
| Gene (human) | GRHL1 (GeneCards) |
| Gene synonyms (human) | LBP32, MGR, TFCP2L2 |
| Gene (mouse) | Grhl1 |
| Gene synonyms (mouse) | Mgr, Tcfcp2l2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 20 |
| Consensus | ndRAACCGGTTWWWCYRGTY |
| GC content | 44.51% |
| Information content (bits; total / per base) | 24.623 / 1.231 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 391 |
| Previous names | GRHL1.H12RSNP.0.PSM.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 3 (20) | 0.547 | 0.551 | 0.444 | 0.452 | 0.904 | 0.924 | 3.998 | 4.358 | 350.217 | 538.77 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.999 | 0.999 | 0.994 | 0.993 | 0.937 | 0.939 |
| best | 1.0 | 1.0 | 0.999 | 0.999 | 0.995 | 0.993 | |
| Methyl HT-SELEX, 2 experiments | median | 0.999 | 0.999 | 0.997 | 0.996 | 0.988 | 0.984 |
| best | 0.999 | 0.999 | 0.997 | 0.996 | 0.99 | 0.986 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.988 | 0.985 | 0.924 | 0.921 | 0.795 | 0.81 |
| best | 1.0 | 1.0 | 0.999 | 0.999 | 0.995 | 0.993 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.926 | 0.73 | 0.894 | 0.587 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | Grainyhead domain factors {6.7} (TFClass) |
| TF family | Grainyhead-related {6.7.1} (TFClass) |
| TF subfamily | GRH-like {6.7.1.1} (TFClass) |
| TFClass ID | TFClass: 6.7.1.1.1 |
| HGNC | HGNC:17923 |
| MGI | MGI:2182540 |
| EntrezGene (human) | GeneID:29841 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:195733 (SSTAR profile) |
| UniProt ID (human) | GRHL1_HUMAN |
| UniProt ID (mouse) | GRHL1_MOUSE |
| UniProt AC (human) | Q9NZI5 (TFClass) |
| UniProt AC (mouse) | Q921D9 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 0 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | GRHL1.H14RSNP.0.PSM.A.pcm |
| PWM | GRHL1.H14RSNP.0.PSM.A.pwm |
| PFM | GRHL1.H14RSNP.0.PSM.A.pfm |
| Threshold to P-value map | GRHL1.H14RSNP.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | GRHL1.H14RSNP.0.PSM.A_jaspar_format.txt |
| MEME format | GRHL1.H14RSNP.0.PSM.A_meme_format.meme |
| Transfac format | GRHL1.H14RSNP.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 137.25 | 69.25 | 109.25 | 75.25 |
| 02 | 168.5 | 53.5 | 85.5 | 83.5 |
| 03 | 276.0 | 10.0 | 62.0 | 43.0 |
| 04 | 386.0 | 0.0 | 4.0 | 1.0 |
| 05 | 391.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 391.0 | 0.0 | 0.0 |
| 07 | 0.0 | 391.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 391.0 | 0.0 |
| 09 | 0.0 | 0.0 | 391.0 | 0.0 |
| 10 | 1.0 | 0.0 | 0.0 | 390.0 |
| 11 | 5.0 | 19.0 | 0.0 | 367.0 |
| 12 | 100.0 | 38.0 | 9.0 | 244.0 |
| 13 | 207.0 | 8.0 | 66.0 | 110.0 |
| 14 | 233.0 | 0.0 | 46.0 | 112.0 |
| 15 | 2.0 | 384.0 | 4.0 | 1.0 |
| 16 | 72.0 | 210.0 | 3.0 | 106.0 |
| 17 | 121.0 | 0.0 | 248.0 | 22.0 |
| 18 | 7.0 | 31.0 | 350.0 | 3.0 |
| 19 | 38.75 | 20.75 | 3.75 | 327.75 |
| 20 | 31.75 | 62.75 | 19.75 | 276.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.351 | 0.177 | 0.279 | 0.192 |
| 02 | 0.431 | 0.137 | 0.219 | 0.214 |
| 03 | 0.706 | 0.026 | 0.159 | 0.11 |
| 04 | 0.987 | 0.0 | 0.01 | 0.003 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 1.0 | 0.0 | 0.0 |
| 07 | 0.0 | 1.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 1.0 | 0.0 |
| 09 | 0.0 | 0.0 | 1.0 | 0.0 |
| 10 | 0.003 | 0.0 | 0.0 | 0.997 |
| 11 | 0.013 | 0.049 | 0.0 | 0.939 |
| 12 | 0.256 | 0.097 | 0.023 | 0.624 |
| 13 | 0.529 | 0.02 | 0.169 | 0.281 |
| 14 | 0.596 | 0.0 | 0.118 | 0.286 |
| 15 | 0.005 | 0.982 | 0.01 | 0.003 |
| 16 | 0.184 | 0.537 | 0.008 | 0.271 |
| 17 | 0.309 | 0.0 | 0.634 | 0.056 |
| 18 | 0.018 | 0.079 | 0.895 | 0.008 |
| 19 | 0.099 | 0.053 | 0.01 | 0.838 |
| 20 | 0.081 | 0.16 | 0.051 | 0.708 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.335 | -0.339 | 0.11 | -0.257 |
| 02 | 0.538 | -0.59 | -0.132 | -0.155 |
| 03 | 1.028 | -2.156 | -0.447 | -0.802 |
| 04 | 1.362 | -4.197 | -2.894 | -3.684 |
| 05 | 1.375 | -4.197 | -4.197 | -4.197 |
| 06 | -4.197 | 1.375 | -4.197 | -4.197 |
| 07 | -4.197 | 1.375 | -4.197 | -4.197 |
| 08 | -4.197 | -4.197 | 1.375 | -4.197 |
| 09 | -4.197 | -4.197 | 1.375 | -4.197 |
| 10 | -3.684 | -4.197 | -4.197 | 1.372 |
| 11 | -2.727 | -1.578 | -4.197 | 1.312 |
| 12 | 0.022 | -0.921 | -2.247 | 0.906 |
| 13 | 0.742 | -2.347 | -0.386 | 0.116 |
| 14 | 0.86 | -4.197 | -0.737 | 0.134 |
| 15 | -3.347 | 1.357 | -2.894 | -3.684 |
| 16 | -0.3 | 0.757 | -3.095 | 0.08 |
| 17 | 0.21 | -4.197 | 0.922 | -1.441 |
| 18 | -2.458 | -1.117 | 1.265 | -3.095 |
| 19 | -0.903 | -1.496 | -2.941 | 1.199 |
| 20 | -1.094 | -0.435 | -1.542 | 1.031 |
| P-value | Threshold |
|---|---|
| 0.001 | -3.43609 |
| 0.0005 | -1.69044 |
| 0.0001 | 2.02671 |