GMEB2.H14INVIVO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GMEB2.H14INVIVO.1.P.C
Gene (human)	GMEB2 (GeneCards)
Gene synonyms (human)	KIAA1269
Gene (mouse)	Gmeb2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	9
Consensus	bKGCGTSMS
GC content	65.37%
Information content (bits; total / per base)	9.165 / 1.018
Data sources	ChIP-Seq
Aligned words	1001
Previous names	GMEB2.H12INVIVO.1.P.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.848	0.853	0.73	0.745	0.712	0.731	1.789	1.87	146.18	158.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 5 experiments	median	0.862	0.789	0.825	0.759	0.72	0.691
Overall, 5 experiments	best	0.949	0.913	0.944	0.903	0.936	0.893
Methyl HT-SELEX, 1 experiments	median	0.949	0.913	0.942	0.902	0.931	0.888
Methyl HT-SELEX, 1 experiments	best	0.949	0.913	0.942	0.902	0.931	0.888
Non-Methyl HT-SELEX, 4 experiments	median	0.784	0.714	0.731	0.68	0.649	0.629
Non-Methyl HT-SELEX, 4 experiments	best	0.947	0.91	0.944	0.903	0.936	0.893

TF superclass	alpha-Helices exposed by beta-structures {5} (TFClass)
TF class	SAND domain factors {5.3} (TFClass)
TF family	GMEB {5.3.3} (TFClass)
TF subfamily	GMEB {5.3.3.1} (TFClass)
TFClass ID	TFClass: 5.3.3.1.2
HGNC	HGNC:4371
MGI	MGI:2652836
EntrezGene (human)	GeneID:26205 (SSTAR profile)
EntrezGene (mouse)	GeneID:229004 (SSTAR profile)
UniProt ID (human)	GMEB2_HUMAN
UniProt ID (mouse)	GMEB2_MOUSE
UniProt AC (human)	Q9UKD1 (TFClass)
UniProt AC (mouse)	P58929 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	GMEB2.H14INVIVO.1.P.C.pcm
PWM	GMEB2.H14INVIVO.1.P.C.pwm
PFM	GMEB2.H14INVIVO.1.P.C.pfm
Threshold to P-value map	GMEB2.H14INVIVO.1.P.C.thr
Motif in other formats
JASPAR format	GMEB2.H14INVIVO.1.P.C_jaspar_format.txt
MEME format	GMEB2.H14INVIVO.1.P.C_meme_format.meme
Transfac format	GMEB2.H14INVIVO.1.P.C_transfac_format.txt
Homer format	GMEB2.H14INVIVO.1.P.C_homer_format_0.001.txt GMEB2.H14INVIVO.1.P.C_homer_format_0.0005.txt GMEB2.H14INVIVO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	37.0	411.0	244.0	309.0
02	103.0	12.0	315.0	571.0
03	315.0	6.0	674.0	6.0
04	9.0	987.0	4.0	1.0
05	7.0	3.0	978.0	13.0
06	2.0	1.0	3.0	995.0
07	50.0	466.0	480.0	5.0
08	493.0	393.0	77.0	38.0
09	33.0	317.0	518.0	133.0

PFM

	A	C	G	T
01	0.037	0.411	0.244	0.309
02	0.103	0.012	0.315	0.57
03	0.315	0.006	0.673	0.006
04	0.009	0.986	0.004	0.001
05	0.007	0.003	0.977	0.013
06	0.002	0.001	0.003	0.994
07	0.05	0.466	0.48	0.005
08	0.493	0.393	0.077	0.038
09	0.033	0.317	0.517	0.133

PWM

	A	C	G	T
01	-1.873	0.493	-0.025	0.21
02	-0.878	-2.91	0.229	0.821
03	0.229	-3.485	0.986	-3.485
04	-3.157	1.367	-3.784	-4.526
05	-3.363	-3.976	1.358	-2.84
06	-4.214	-4.526	-3.976	1.375
07	-1.583	0.619	0.648	-3.623
08	0.675	0.449	-1.163	-1.847
09	-1.982	0.235	0.724	-0.626

Standard thresholds

P-value	Threshold
0.001	5.213335
0.0005	6.09159
0.0001	7.46175