MotifGATA2.H14INVIVO.1.P.B
Gene (human)GATA2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusbdbnnnnndvAGATAASv
GC content44.76%
Information content (bits; total / per base)11.507 / 0.639
Data sourcesChIP-Seq
Aligned words977
Previous namesGATA2.H12INVIVO.1.P.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 41 (254) 0.843 0.954 0.716 0.903 0.828 0.945 2.613 4.151 178.616 332.143
Mouse 23 (136) 0.802 0.959 0.678 0.904 0.784 0.955 2.473 4.178 140.376 337.658

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.913 0.862 0.884 0.831 0.836 0.786
best 0.924 0.874 0.901 0.849 0.862 0.811
Methyl HT-SELEX, 1 experiments median 0.924 0.874 0.901 0.849 0.862 0.811
best 0.924 0.874 0.901 0.849 0.862 0.811
Non-Methyl HT-SELEX, 1 experiments median 0.903 0.85 0.867 0.812 0.811 0.762
best 0.903 0.85 0.867 0.812 0.811 0.762

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.942 4.58 0.235 0.113

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.65 0.286 0.616 0.425
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.2
HGNCHGNC:4171
MGIMGI:95662
EntrezGene (human)GeneID:2624
(SSTAR profile)
EntrezGene (mouse)GeneID:14461
(SSTAR profile)
UniProt ID (human)GATA2_HUMAN
UniProt ID (mouse)GATA2_MOUSE
UniProt AC (human)P23769
(TFClass)
UniProt AC (mouse)O09100
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 41 human, 23 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01134.0238.0168.0437.0
02106.095.0452.0324.0
03136.0215.0423.0203.0
04225.0214.0302.0236.0
05296.0187.0301.0193.0
06205.0183.0366.0223.0
07214.0213.0351.0199.0
08186.0241.0258.0292.0
09305.0133.0347.0192.0
10172.0379.0341.085.0
11701.010.09.0257.0
121.01.0975.00.0
13974.01.00.02.0
142.03.08.0964.0
15925.06.013.033.0
16845.09.092.031.0
17133.0136.0639.069.0
18345.0210.0353.069.0
PFM
ACGT
010.1370.2440.1720.447
020.1080.0970.4630.332
030.1390.220.4330.208
040.230.2190.3090.242
050.3030.1910.3080.198
060.210.1870.3750.228
070.2190.2180.3590.204
080.190.2470.2640.299
090.3120.1360.3550.197
100.1760.3880.3490.087
110.7180.010.0090.263
120.0010.0010.9980.0
130.9970.0010.00.002
140.0020.0030.0080.987
150.9470.0060.0130.034
160.8650.0090.0940.032
170.1360.1390.6540.071
180.3530.2150.3610.071
PWM
ACGT
01-0.595-0.026-0.3710.579
02-0.826-0.9330.6120.281
03-0.58-0.1270.546-0.184
04-0.081-0.1310.211-0.034
050.191-0.2650.208-0.234
06-0.174-0.2860.402-0.09
07-0.131-0.1360.36-0.203
08-0.27-0.0130.0540.177
090.221-0.6020.349-0.239
10-0.3480.4370.332-1.043
111.05-3.044-3.1330.051
12-4.504-4.5041.379-4.962
131.378-4.504-4.962-4.191
14-4.191-3.953-3.2311.368
151.326-3.461-2.816-1.958
161.236-3.133-0.965-2.017
17-0.602-0.580.957-1.246
180.343-0.150.366-1.246
Standard thresholds
P-value Threshold
0.001 4.22851
0.0005 5.33836
0.0001 7.48216