FXL19.H14INVIVO.0.PSGIB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FXL19.H14INVIVO.0.PSGIB.A
Gene (human)	FBXL19 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Fbxl19
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	21
Consensus	KRRMRGvRRMRGvdRvRGvRv
GC content	73.23%
Information content (bits; total / per base)	13.636 / 0.649
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	999
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.703	0.719	0.47	0.493	0.738	0.747	0.054	0.108

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.472	0.487	0.471	0.486	0.477	0.487
overall, 3 experiments	best	0.479	0.489	0.483	0.491	0.485	0.492
Lysate, 1 experiments	median	0.451	0.474	0.458	0.477	0.462	0.48
Lysate, 1 experiments	best	0.451	0.474	0.458	0.477	0.462	0.48
IVT, 1 experiments	median	0.479	0.489	0.483	0.491	0.485	0.492
IVT, 1 experiments	best	0.479	0.489	0.483	0.491	0.485	0.492
GFPIVT, 1 experiments	median	0.472	0.487	0.471	0.486	0.477	0.487
GFPIVT, 1 experiments	best	0.472	0.487	0.471	0.486	0.477	0.487

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 1 experiments	median	0.0	0.668	0.584	0.394
Lysate, 1 experiments	best	0.0	0.691	0.603	0.406

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.437	0.468	0.448	0.472	0.461	0.477
Overall, 2 experiments	best	0.443	0.473	0.453	0.475	0.465	0.48

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 4 experiments	median	0.557	0.002	0.516	0.011
Overall, 4 experiments	best	0.574	0.002	0.526	0.014

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	CXXC zinc finger factors {2.6} (TFClass)
TF family	CpG-binding {2.6.1} (TFClass)
TF subfamily	{2.6.1.0} (TFClass)
TFClass ID	TFClass: 2.6.1.0.256
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	FXL19_HUMAN
UniProt ID (mouse)	FXL19_MOUSE
UniProt AC (human)	Q6PCT2 (TFClass)
UniProt AC (mouse)	Q6PB97 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3 overall: 1 Lysate, 1 IVT, 1 GFPIVT
Genomic HT-SELEX	1 overall: 1 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	2
PBM	4

PCM	FXL19.H14INVIVO.0.PSGIB.A.pcm
PWM	FXL19.H14INVIVO.0.PSGIB.A.pwm
PFM	FXL19.H14INVIVO.0.PSGIB.A.pfm
Threshold to P-value map	FXL19.H14INVIVO.0.PSGIB.A.thr
Motif in other formats
JASPAR format	FXL19.H14INVIVO.0.PSGIB.A_jaspar_format.txt
MEME format	FXL19.H14INVIVO.0.PSGIB.A_meme_format.meme
Transfac format	FXL19.H14INVIVO.0.PSGIB.A_transfac_format.txt
Homer format	FXL19.H14INVIVO.0.PSGIB.A_homer_format_0.001.txt FXL19.H14INVIVO.0.PSGIB.A_homer_format_0.0005.txt FXL19.H14INVIVO.0.PSGIB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	60.0	22.0	763.0	154.0
02	185.0	132.0	667.0	15.0
03	167.0	84.0	737.0	11.0
04	480.0	477.0	8.0	34.0
05	189.0	42.0	677.0	91.0
06	103.0	26.0	834.0	36.0
07	335.0	356.0	252.0	56.0
08	198.0	49.0	718.0	34.0
09	132.0	88.0	771.0	8.0
10	393.0	483.0	78.0	45.0
11	221.0	86.0	617.0	75.0
12	133.0	28.0	814.0	24.0
13	208.0	425.0	326.0	40.0
14	252.0	99.0	532.0	116.0
15	158.0	71.0	715.0	55.0
16	279.0	508.0	129.0	83.0
17	135.0	52.0	723.0	89.0
18	76.0	101.0	800.0	22.0
19	302.0	321.0	320.0	56.0
20	245.0	75.0	615.0	64.0
21	220.0	193.0	549.0	37.0

PFM

	A	C	G	T
01	0.06	0.022	0.764	0.154
02	0.185	0.132	0.668	0.015
03	0.167	0.084	0.738	0.011
04	0.48	0.477	0.008	0.034
05	0.189	0.042	0.678	0.091
06	0.103	0.026	0.835	0.036
07	0.335	0.356	0.252	0.056
08	0.198	0.049	0.719	0.034
09	0.132	0.088	0.772	0.008
10	0.393	0.483	0.078	0.045
11	0.221	0.086	0.618	0.075
12	0.133	0.028	0.815	0.024
13	0.208	0.425	0.326	0.04
14	0.252	0.099	0.533	0.116
15	0.158	0.071	0.716	0.055
16	0.279	0.509	0.129	0.083
17	0.135	0.052	0.724	0.089
18	0.076	0.101	0.801	0.022
19	0.302	0.321	0.32	0.056
20	0.245	0.075	0.616	0.064
21	0.22	0.193	0.55	0.037

PWM

	A	C	G	T
01	-1.405	-2.361	1.112	-0.479
02	-0.298	-0.632	0.978	-2.71
03	-0.399	-1.076	1.078	-2.984
04	0.65	0.644	-3.252	-1.951
05	-0.277	-1.749	0.993	-0.998
06	-0.876	-2.205	1.201	-1.897
07	0.292	0.352	0.009	-1.472
08	-0.23	-1.601	1.052	-1.951
09	-0.632	-1.031	1.123	-3.252
10	0.451	0.656	-1.149	-1.683
11	-0.121	-1.053	0.9	-1.187
12	-0.624	-2.135	1.177	-2.28
13	-0.182	0.529	0.265	-1.796
14	0.009	-0.915	0.753	-0.759
15	-0.454	-1.241	1.047	-1.489
16	0.11	0.707	-0.654	-1.088
17	-0.609	-1.543	1.058	-1.019
18	-1.174	-0.895	1.159	-2.361
19	0.189	0.249	0.246	-1.472
20	-0.019	-1.187	0.897	-1.342
21	-0.126	-0.256	0.784	-1.871

Standard thresholds

P-value	Threshold
0.001	3.85826
0.0005	4.81171
0.0001	6.82981