FOXR2.H14INVITRO.0.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXR2.H14INVITRO.0.M.C
Gene (human)	FOXR2 (GeneCards)
Gene synonyms (human)	FOXN6
Gene (mouse)	Foxr2
Gene synonyms (mouse)	Foxn6
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	15
Consensus	dTWTAYRTWTAYRYn
GC content	21.65%
Information content (bits; total / per base)	14.985 / 0.999
Data sources	Methyl-HT-SELEX
Aligned words	7796
Previous names	FOXR2.H12INVITRO.0.M.C

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.993	0.99	0.95	0.943	0.797	0.811
Methyl HT-SELEX, 1 experiments	best	0.993	0.99	0.95	0.943	0.797	0.811

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.904	0.289	0.877	0.555
batch 2	0.554	0.168	0.543	0.561

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXR {3.3.1.18} (TFClass)
TFClass ID	TFClass: 3.3.1.18.2
HGNC	HGNC:30469
MGI	MGI:3511682
EntrezGene (human)	GeneID:139628 (SSTAR profile)
EntrezGene (mouse)	GeneID:436240 (SSTAR profile)
UniProt ID (human)	FOXR2_HUMAN
UniProt ID (mouse)	FOXR2_MOUSE
UniProt AC (human)	Q6PJQ5 (TFClass)
UniProt AC (mouse)	Q3UM89 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOXR2.H14INVITRO.0.M.C.pcm
PWM	FOXR2.H14INVITRO.0.M.C.pwm
PFM	FOXR2.H14INVITRO.0.M.C.pfm
Threshold to P-value map	FOXR2.H14INVITRO.0.M.C.thr
Motif in other formats
JASPAR format	FOXR2.H14INVITRO.0.M.C_jaspar_format.txt
MEME format	FOXR2.H14INVITRO.0.M.C_meme_format.meme
Transfac format	FOXR2.H14INVITRO.0.M.C_transfac_format.txt
Homer format	FOXR2.H14INVITRO.0.M.C_homer_format_0.001.txt FOXR2.H14INVITRO.0.M.C_homer_format_0.0005.txt FOXR2.H14INVITRO.0.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	4286.5	946.5	1438.5	1124.5
02	270.75	454.75	409.75	6660.75
03	1957.0	393.0	607.0	4839.0
04	138.0	71.0	28.0	7559.0
05	7558.0	6.0	185.0	47.0
06	25.0	1574.0	873.0	5324.0
07	3059.0	24.0	4700.0	13.0
08	3.0	461.0	0.0	7332.0
09	3782.0	560.0	57.0	3397.0
10	18.0	21.0	15.0	7742.0
11	7109.0	25.0	607.0	55.0
12	70.0	1990.0	613.0	5123.0
13	3580.0	441.0	3451.0	324.0
14	594.75	1686.75	555.75	4958.75
15	2406.5	1494.5	1631.5	2263.5

PFM

	A	C	G	T
01	0.55	0.121	0.185	0.144
02	0.035	0.058	0.053	0.854
03	0.251	0.05	0.078	0.621
04	0.018	0.009	0.004	0.97
05	0.969	0.001	0.024	0.006
06	0.003	0.202	0.112	0.683
07	0.392	0.003	0.603	0.002
08	0.0	0.059	0.0	0.94
09	0.485	0.072	0.007	0.436
10	0.002	0.003	0.002	0.993
11	0.912	0.003	0.078	0.007
12	0.009	0.255	0.079	0.657
13	0.459	0.057	0.443	0.042
14	0.076	0.216	0.071	0.636
15	0.309	0.192	0.209	0.29

PWM

	A	C	G	T
01	0.788	-0.721	-0.303	-0.549
02	-1.967	-1.452	-1.555	1.228
03	0.004	-1.597	-1.164	0.909
04	-2.633	-3.282	-4.167	1.355
05	1.354	-5.467	-2.344	-3.68
06	-4.272	-0.213	-0.802	1.004
07	0.45	-4.309	0.88	-4.852
08	-5.92	-1.438	-6.77	1.324
09	0.662	-1.244	-3.495	0.555
10	-4.569	-4.43	-4.729	1.378
11	1.293	-4.272	-1.164	-3.529
12	-3.296	0.021	-1.154	0.966
13	0.608	-1.482	0.571	-1.789
14	-1.184	-0.144	-1.252	0.933
15	0.211	-0.265	-0.178	0.149

Standard thresholds

P-value	Threshold
0.001	2.50696
0.0005	3.81591
0.0001	6.50166