FOXP1.H14INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXP1.H14INVIVO.0.PS.A
Gene (human)	FOXP1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Foxp1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	bbTGTTKWY
GC content	39.38%
Information content (bits; total / per base)	8.704 / 0.967
Data sources	ChIP-Seq + HT-SELEX
Aligned words	882
Previous names	FOXP1.H12INVIVO.0.PS.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	11 (71)	0.697	0.914	0.579	0.86	0.71	0.876	2.095	2.979	42.319	193.921
Mouse	4 (22)	0.644	0.845	0.56	0.751	0.675	0.847	2.033	2.834	19.067	254.26

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.874	0.833	0.806	0.762	0.704	0.686
Non-Methyl HT-SELEX, 1 experiments	best	0.874	0.833	0.806	0.762	0.704	0.686

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.069	1.022	0.079	0.14

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXP {3.3.1.16} (TFClass)
TFClass ID	TFClass: 3.3.1.16.1
HGNC	HGNC:3823
MGI	MGI:1914004
EntrezGene (human)	GeneID:27086 (SSTAR profile)
EntrezGene (mouse)	GeneID:108655 (SSTAR profile)
UniProt ID (human)	FOXP1_HUMAN
UniProt ID (mouse)	FOXP1_MOUSE
UniProt AC (human)	Q9H334 (TFClass)
UniProt AC (mouse)	P58462 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	11 human, 4 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOXP1.H14INVIVO.0.PS.A.pcm
PWM	FOXP1.H14INVIVO.0.PS.A.pwm
PFM	FOXP1.H14INVIVO.0.PS.A.pfm
Threshold to P-value map	FOXP1.H14INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	FOXP1.H14INVIVO.0.PS.A_jaspar_format.txt
MEME format	FOXP1.H14INVIVO.0.PS.A_meme_format.meme
Transfac format	FOXP1.H14INVIVO.0.PS.A_transfac_format.txt
Homer format	FOXP1.H14INVIVO.0.PS.A_homer_format_0.001.txt FOXP1.H14INVIVO.0.PS.A_homer_format_0.0005.txt FOXP1.H14INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	84.0	213.0	317.0	268.0
02	56.0	290.0	242.0	294.0
03	22.0	5.0	8.0	847.0
04	24.0	13.0	835.0	10.0
05	5.0	34.0	12.0	831.0
06	6.0	5.0	118.0	753.0
07	5.0	13.0	304.0	560.0
08	481.0	88.0	39.0	274.0
09	8.0	539.0	51.0	284.0

PFM

	A	C	G	T
01	0.095	0.241	0.359	0.304
02	0.063	0.329	0.274	0.333
03	0.025	0.006	0.009	0.96
04	0.027	0.015	0.947	0.011
05	0.006	0.039	0.014	0.942
06	0.007	0.006	0.134	0.854
07	0.006	0.015	0.345	0.635
08	0.545	0.1	0.044	0.311
09	0.009	0.611	0.058	0.322

PWM

	A	C	G	T
01	-0.953	-0.034	0.361	0.194
02	-1.348	0.272	0.092	0.286
03	-2.238	-3.502	-3.132	1.34
04	-2.157	-2.716	1.326	-2.944
05	-3.502	-1.829	-2.786	1.321
06	-3.363	-3.502	-0.619	1.223
07	-3.502	-2.716	0.319	0.927
08	0.776	-0.907	-1.697	0.216
09	-3.132	0.889	-1.439	0.251

Standard thresholds

P-value	Threshold
0.001	5.027265
0.0005	5.95151
0.0001	7.468105