| Motif | FOXO3.H14INVIVO.0.PS.A |
| Gene (human) | FOXO3 (GeneCards) |
| Gene synonyms (human) | FKHRL1, FOXO3A |
| Gene (mouse) | Foxo3 |
| Gene synonyms (mouse) | Fkhr2, Foxo3a |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | FOXO3.H14INVIVO.0.PS.A |
| Gene (human) | FOXO3 (GeneCards) |
| Gene synonyms (human) | FKHRL1, FOXO3A |
| Gene (mouse) | Foxo3 |
| Gene synonyms (mouse) | Fkhr2, Foxo3a |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 10 |
| Consensus | bbTGTTTACh |
| GC content | 36.64% |
| Information content (bits; total / per base) | 11.442 / 1.144 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 1001 |
| Previous names | FOXO3.H12INVIVO.0.PS.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 1 (7) | 0.874 | 0.886 | 0.797 | 0.823 | 0.894 | 0.91 | 3.566 | 3.718 | 275.201 | 297.678 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.71 | 0.68 | 0.616 | 0.607 | 0.56 | 0.565 |
| best | 0.717 | 0.687 | 0.619 | 0.611 | 0.562 | 0.567 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | FOX {3.3.1} (TFClass) |
| TF subfamily | FOXO {3.3.1.15} (TFClass) |
| TFClass ID | TFClass: 3.3.1.15.2 |
| HGNC | HGNC:3821 |
| MGI | MGI:1890081 |
| EntrezGene (human) | GeneID:2309 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:56484 (SSTAR profile) |
| UniProt ID (human) | FOXO3_HUMAN |
| UniProt ID (mouse) | FOXO3_MOUSE |
| UniProt AC (human) | O43524 (TFClass) |
| UniProt AC (mouse) | Q9WVH4 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 1 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | FOXO3.H14INVIVO.0.PS.A.pcm |
| PWM | FOXO3.H14INVIVO.0.PS.A.pwm |
| PFM | FOXO3.H14INVIVO.0.PS.A.pfm |
| Threshold to P-value map | FOXO3.H14INVIVO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | FOXO3.H14INVIVO.0.PS.A_jaspar_format.txt |
| MEME format | FOXO3.H14INVIVO.0.PS.A_meme_format.meme |
| Transfac format | FOXO3.H14INVIVO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 111.0 | 414.0 | 306.0 | 170.0 |
| 02 | 60.0 | 384.0 | 170.0 | 387.0 |
| 03 | 10.0 | 1.0 | 1.0 | 989.0 |
| 04 | 49.0 | 6.0 | 943.0 | 3.0 |
| 05 | 2.0 | 7.0 | 14.0 | 978.0 |
| 06 | 5.0 | 7.0 | 35.0 | 954.0 |
| 07 | 0.0 | 10.0 | 148.0 | 843.0 |
| 08 | 839.0 | 50.0 | 14.0 | 98.0 |
| 09 | 5.0 | 848.0 | 8.0 | 140.0 |
| 10 | 387.0 | 245.0 | 57.0 | 312.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.111 | 0.414 | 0.306 | 0.17 |
| 02 | 0.06 | 0.384 | 0.17 | 0.387 |
| 03 | 0.01 | 0.001 | 0.001 | 0.988 |
| 04 | 0.049 | 0.006 | 0.942 | 0.003 |
| 05 | 0.002 | 0.007 | 0.014 | 0.977 |
| 06 | 0.005 | 0.007 | 0.035 | 0.953 |
| 07 | 0.0 | 0.01 | 0.148 | 0.842 |
| 08 | 0.838 | 0.05 | 0.014 | 0.098 |
| 09 | 0.005 | 0.847 | 0.008 | 0.14 |
| 10 | 0.387 | 0.245 | 0.057 | 0.312 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.804 | 0.501 | 0.2 | -0.383 |
| 02 | -1.407 | 0.426 | -0.383 | 0.434 |
| 03 | -3.067 | -4.526 | -4.526 | 1.369 |
| 04 | -1.603 | -3.485 | 1.322 | -3.976 |
| 05 | -4.214 | -3.363 | -2.774 | 1.358 |
| 06 | -3.623 | -3.363 | -1.926 | 1.333 |
| 07 | -4.983 | -3.067 | -0.521 | 1.21 |
| 08 | 1.205 | -1.583 | -2.774 | -0.927 |
| 09 | -3.623 | 1.216 | -3.254 | -0.575 |
| 10 | 0.434 | -0.021 | -1.456 | 0.219 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.24817 |
| 0.0005 | 5.29523 |
| 0.0001 | 7.437235 |