FOXD3.H14RSNP.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOXD3.H14RSNP.0.P.D
Gene (human)	FOXD3 (GeneCards)
Gene synonyms (human)	HFH2
Gene (mouse)	Foxd3
Gene synonyms (mouse)	Hfh2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	14
Consensus	nnTGTYKnYhYWvn
GC content	39.12%
Information content (bits; total / per base)	7.704 / 0.55
Data sources	ChIP-Seq
Aligned words	997
Previous names	FOXD3.H12RSNP.0.P.D

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.684	0.717	0.495	0.559	0.753	0.786	2.175	2.496	62.921	89.347

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.626	0.614	0.57	0.566	0.535	0.54
Non-Methyl HT-SELEX, 2 experiments	best	0.71	0.693	0.617	0.613	0.558	0.567

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	FOX {3.3.1} (TFClass)
TF subfamily	FOXD {3.3.1.4} (TFClass)
TFClass ID	TFClass: 3.3.1.4.3
HGNC	HGNC:3804
MGI	MGI:1347473
EntrezGene (human)	GeneID:27022 (SSTAR profile)
EntrezGene (mouse)	GeneID:15221 (SSTAR profile)
UniProt ID (human)	FOXD3_HUMAN
UniProt ID (mouse)	FOXD3_MOUSE
UniProt AC (human)	Q9UJU5 (TFClass)
UniProt AC (mouse)	Q61060 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOXD3.H14RSNP.0.P.D.pcm
PWM	FOXD3.H14RSNP.0.P.D.pwm
PFM	FOXD3.H14RSNP.0.P.D.pfm
Threshold to P-value map	FOXD3.H14RSNP.0.P.D.thr
Motif in other formats
JASPAR format	FOXD3.H14RSNP.0.P.D_jaspar_format.txt
MEME format	FOXD3.H14RSNP.0.P.D_meme_format.meme
Transfac format	FOXD3.H14RSNP.0.P.D_transfac_format.txt
Homer format	FOXD3.H14RSNP.0.P.D_homer_format_0.001.txt FOXD3.H14RSNP.0.P.D_homer_format_0.0005.txt FOXD3.H14RSNP.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	196.0	196.0	303.0	302.0
02	152.0	269.0	242.0	334.0
03	177.0	10.0	44.0	766.0
04	36.0	75.0	880.0	6.0
05	61.0	72.0	29.0	835.0
06	43.0	89.0	63.0	802.0
07	50.0	7.0	180.0	760.0
08	324.0	167.0	253.0	253.0
09	16.0	600.0	53.0	328.0
10	274.0	196.0	40.0	487.0
11	93.0	234.0	80.0	590.0
12	438.0	29.0	115.0	415.0
13	233.0	165.0	436.0	163.0
14	135.0	308.0	326.0	228.0

PFM

	A	C	G	T
01	0.197	0.197	0.304	0.303
02	0.152	0.27	0.243	0.335
03	0.178	0.01	0.044	0.768
04	0.036	0.075	0.883	0.006
05	0.061	0.072	0.029	0.838
06	0.043	0.089	0.063	0.804
07	0.05	0.007	0.181	0.762
08	0.325	0.168	0.254	0.254
09	0.016	0.602	0.053	0.329
10	0.275	0.197	0.04	0.488
11	0.093	0.235	0.08	0.592
12	0.439	0.029	0.115	0.416
13	0.234	0.165	0.437	0.163
14	0.135	0.309	0.327	0.229

PWM

	A	C	G	T
01	-0.238	-0.238	0.194	0.191
02	-0.49	0.076	-0.029	0.291
03	-0.34	-3.064	-1.703	1.118
04	-1.895	-1.185	1.257	-3.481
05	-1.387	-1.225	-2.1	1.204
06	-1.725	-1.018	-1.355	1.164
07	-1.579	-3.359	-0.323	1.11
08	0.261	-0.397	0.015	0.015
09	-2.65	0.874	-1.523	0.273
10	0.094	-0.238	-1.794	0.666
11	-0.974	-0.063	-1.122	0.858
12	0.561	-2.1	-0.766	0.507
13	-0.067	-0.409	0.556	-0.421
14	-0.607	0.21	0.267	-0.088

Standard thresholds

P-value	Threshold
0.001	5.00091
0.0005	5.66906
0.0001	7.02146