FOSL2.H14INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOSL2.H14INVIVO.0.P.B
Gene (human)	FOSL2 (GeneCards)
Gene synonyms (human)	FRA2
Gene (mouse)	Fosl2
Gene synonyms (mouse)	Fra-2, Fra2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	ndRTGAGTCAYh
GC content	44.87%
Information content (bits; total / per base)	14.091 / 1.174
Data sources	ChIP-Seq
Aligned words	500
Previous names	FOSL2.H12INVIVO.0.P.B; FOSL2_HUMAN.H11MO.0.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	28 (191)	0.962	0.992	0.92	0.98	0.964	0.987	4.424	5.24	335.18	753.77
Mouse	11 (71)	0.957	0.992	0.917	0.979	0.959	0.991	4.377	5.348	450.301	657.137

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	14.153	2.893	0.335	0.273

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.4
HGNC	HGNC:3798
MGI	MGI:102858
EntrezGene (human)	GeneID:2355 (SSTAR profile)
EntrezGene (mouse)	GeneID:14284 (SSTAR profile)
UniProt ID (human)	FOSL2_HUMAN
UniProt ID (mouse)	FOSL2_MOUSE
UniProt AC (human)	P15408 (TFClass)
UniProt AC (mouse)	P47930 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	28 human, 11 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOSL2.H14INVIVO.0.P.B.pcm
PWM	FOSL2.H14INVIVO.0.P.B.pwm
PFM	FOSL2.H14INVIVO.0.P.B.pfm
Threshold to P-value map	FOSL2.H14INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	FOSL2.H14INVIVO.0.P.B_jaspar_format.txt
MEME format	FOSL2.H14INVIVO.0.P.B_meme_format.meme
Transfac format	FOSL2.H14INVIVO.0.P.B_transfac_format.txt
Homer format	FOSL2.H14INVIVO.0.P.B_homer_format_0.001.txt FOSL2.H14INVIVO.0.P.B_homer_format_0.0005.txt FOSL2.H14INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	97.0	95.0	187.0	121.0
02	141.0	67.0	191.0	101.0
03	260.0	79.0	149.0	12.0
04	0.0	0.0	1.0	499.0
05	0.0	1.0	479.0	20.0
06	493.0	2.0	0.0	5.0
07	51.0	0.0	449.0	0.0
08	2.0	2.0	2.0	494.0
09	3.0	496.0	1.0	0.0
10	499.0	0.0	0.0	1.0
11	12.0	176.0	57.0	255.0
12	108.0	189.0	69.0	134.0

PFM

	A	C	G	T
01	0.194	0.19	0.374	0.242
02	0.282	0.134	0.382	0.202
03	0.52	0.158	0.298	0.024
04	0.0	0.0	0.002	0.998
05	0.0	0.002	0.958	0.04
06	0.986	0.004	0.0	0.01
07	0.102	0.0	0.898	0.0
08	0.004	0.004	0.004	0.988
09	0.006	0.992	0.002	0.0
10	0.998	0.0	0.0	0.002
11	0.024	0.352	0.114	0.51
12	0.216	0.378	0.138	0.268

PWM

	A	C	G	T
01	-0.25	-0.271	0.399	-0.032
02	0.119	-0.613	0.42	-0.21
03	0.726	-0.452	0.174	-2.234
04	-4.4	-4.4	-3.903	1.375
05	-4.4	-3.903	1.334	-1.77
06	1.363	-3.573	-4.4	-2.961
07	-0.879	-4.4	1.27	-4.4
08	-3.573	-3.573	-3.573	1.365
09	-3.325	1.369	-3.903	-4.4
10	1.375	-4.4	-4.4	-3.903
11	-2.234	0.339	-0.771	0.707
12	-0.144	0.409	-0.584	0.069

Standard thresholds

P-value	Threshold
0.001	2.886955
0.0005	4.24394
0.0001	6.57649