FOS.H14CORE.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOS.H14CORE.1.S.C
Gene (human)	FOS (GeneCards)
Gene synonyms (human)	G0S7
Gene (mouse)	Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	10
Consensus	nvYGTCATbn
GC content	51.09%
Information content (bits; total / per base)	9.492 / 0.949
Data sources	HT-SELEX
Aligned words	8573
Previous names	FOS.H12CORE.1.S.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	25 (159)	0.665	0.794	0.458	0.6	0.587	0.689	1.215	1.626	34.102	102.824
Mouse	27 (180)	0.693	0.772	0.486	0.612	0.601	0.684	1.279	1.674	30.208	89.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.898	0.864	0.813	0.779	0.7	0.691
Non-Methyl HT-SELEX, 1 experiments	best	0.898	0.864	0.813	0.779	0.7	0.691

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.603	0.017	0.139	0.148

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.1
HGNC	HGNC:3796
MGI	MGI:95574
EntrezGene (human)	GeneID:2353 (SSTAR profile)
EntrezGene (mouse)	GeneID:14281 (SSTAR profile)
UniProt ID (human)	FOS_HUMAN
UniProt ID (mouse)	FOS_MOUSE
UniProt AC (human)	P01100 (TFClass)
UniProt AC (mouse)	P01101 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	25 human, 27 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOS.H14CORE.1.S.C.pcm
PWM	FOS.H14CORE.1.S.C.pwm
PFM	FOS.H14CORE.1.S.C.pfm
Threshold to P-value map	FOS.H14CORE.1.S.C.thr
Motif in other formats
JASPAR format	FOS.H14CORE.1.S.C_jaspar_format.txt
MEME format	FOS.H14CORE.1.S.C_meme_format.meme
Transfac format	FOS.H14CORE.1.S.C_transfac_format.txt
Homer format	FOS.H14CORE.1.S.C_homer_format_0.001.txt FOS.H14CORE.1.S.C_homer_format_0.0005.txt FOS.H14CORE.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1684.25	2497.25	2307.25	2084.25
02	2895.25	1470.25	3002.25	1205.25
03	371.0	5350.0	611.0	2241.0
04	568.0	252.0	7719.0	34.0
05	0.0	1.0	0.0	8572.0
06	18.0	8555.0	0.0	0.0
07	8417.0	155.0	1.0	0.0
08	54.0	1490.0	57.0	6972.0
09	1175.75	4253.75	1450.75	1692.75
10	2802.5	2502.5	2122.5	1145.5

PFM

	A	C	G	T
01	0.196	0.291	0.269	0.243
02	0.338	0.171	0.35	0.141
03	0.043	0.624	0.071	0.261
04	0.066	0.029	0.9	0.004
05	0.0	0.0	0.0	1.0
06	0.002	0.998	0.0	0.0
07	0.982	0.018	0.0	0.0
08	0.006	0.174	0.007	0.813
09	0.137	0.496	0.169	0.197
10	0.327	0.292	0.248	0.134

PWM

	A	C	G	T
01	-0.241	0.153	0.074	-0.028
02	0.3	-0.376	0.337	-0.575
03	-1.749	0.914	-1.252	0.045
04	-1.325	-2.133	1.281	-4.08
05	-6.854	-6.488	-6.854	1.385
06	-4.662	1.383	-6.854	-6.854
07	1.367	-2.613	-6.488	-6.854
08	-3.641	-0.363	-3.589	1.179
09	-0.6	0.685	-0.39	-0.236
10	0.268	0.155	-0.01	-0.626

Standard thresholds

P-value	Threshold
0.001	5.153315
0.0005	6.10106
0.0001	7.583535