ETV7.H14INVIVO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV7.H14INVIVO.0.SM.B
Gene (human)	ETV7 (GeneCards)
Gene synonyms (human)	TEL2, TELB, TREF
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	nddhvvGGAARYdnddvvn
GC content	49.04%
Information content (bits; total / per base)	10.598 / 0.558
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9936
Previous names	ETV7.H12INVIVO.0.SM.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.639	0.65	0.475	0.492	0.635	0.646	1.541	1.589	2.569	4.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.978	0.974	0.898	0.899	0.809	0.821
Overall, 2 experiments	best	0.999	0.999	0.995	0.994	0.962	0.958
Methyl HT-SELEX, 1 experiments	median	0.956	0.948	0.801	0.804	0.656	0.685
Methyl HT-SELEX, 1 experiments	best	0.956	0.948	0.801	0.804	0.656	0.685
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.995	0.994	0.962	0.958
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.995	0.994	0.962	0.958

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.803	0.371	0.67	0.407

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETV6-like {3.5.2.6} (TFClass)
TFClass ID	TFClass: 3.5.2.6.2
HGNC	HGNC:18160
MGI
EntrezGene (human)	GeneID:51513 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ETV7_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9Y603 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ETV7.H14INVIVO.0.SM.B.pcm
PWM	ETV7.H14INVIVO.0.SM.B.pwm
PFM	ETV7.H14INVIVO.0.SM.B.pfm
Threshold to P-value map	ETV7.H14INVIVO.0.SM.B.thr
Motif in other formats
JASPAR format	ETV7.H14INVIVO.0.SM.B_jaspar_format.txt
MEME format	ETV7.H14INVIVO.0.SM.B_meme_format.meme
Transfac format	ETV7.H14INVIVO.0.SM.B_transfac_format.txt
Homer format	ETV7.H14INVIVO.0.SM.B_homer_format_0.001.txt ETV7.H14INVIVO.0.SM.B_homer_format_0.0005.txt ETV7.H14INVIVO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2014.0	2543.0	2042.0	3337.0
02	2321.75	1627.75	1829.75	4156.75
03	2998.0	1115.0	1744.0	4079.0
04	2342.0	4072.0	1705.0	1817.0
05	1685.0	4952.0	2125.0	1174.0
06	4127.0	3088.0	1547.0	1174.0
07	36.0	32.0	9820.0	48.0
08	13.0	43.0	9788.0	92.0
09	9837.0	13.0	12.0	74.0
10	9620.0	107.0	20.0	189.0
11	3032.0	202.0	6633.0	69.0
12	710.0	1880.0	678.0	6668.0
13	4496.0	739.0	3383.0	1318.0
14	2207.0	3379.0	2121.0	2229.0
15	2036.0	1818.0	1825.0	4257.0
16	1828.0	1812.0	1899.0	4397.0
17	1835.0	4467.0	1937.0	1697.0
18	1824.75	4318.75	2127.75	1664.75
19	2212.5	1889.5	3250.5	2583.5

PFM

	A	C	G	T
01	0.203	0.256	0.206	0.336
02	0.234	0.164	0.184	0.418
03	0.302	0.112	0.176	0.411
04	0.236	0.41	0.172	0.183
05	0.17	0.498	0.214	0.118
06	0.415	0.311	0.156	0.118
07	0.004	0.003	0.988	0.005
08	0.001	0.004	0.985	0.009
09	0.99	0.001	0.001	0.007
10	0.968	0.011	0.002	0.019
11	0.305	0.02	0.668	0.007
12	0.071	0.189	0.068	0.671
13	0.452	0.074	0.34	0.133
14	0.222	0.34	0.213	0.224
15	0.205	0.183	0.184	0.428
16	0.184	0.182	0.191	0.443
17	0.185	0.45	0.195	0.171
18	0.184	0.435	0.214	0.168
19	0.223	0.19	0.327	0.26

PWM

	A	C	G	T
01	-0.21	0.023	-0.196	0.295
02	-0.067	-0.422	-0.305	0.514
03	0.188	-0.8	-0.353	0.496
04	-0.059	0.494	-0.376	-0.312
05	-0.388	0.689	-0.156	-0.748
06	0.507	0.217	-0.473	-0.748
07	-4.173	-4.283	1.374	-3.901
08	-5.091	-4.005	1.371	-3.272
09	1.376	-5.091	-5.158	-3.484
10	1.353	-3.124	-4.714	-2.565
11	0.199	-2.499	0.982	-3.552
12	-1.25	-0.278	-1.296	0.987
13	0.593	-1.21	0.309	-0.633
14	-0.118	0.307	-0.158	-0.108
15	-0.199	-0.312	-0.308	0.538
16	-0.306	-0.315	-0.268	0.571
17	-0.302	0.586	-0.248	-0.381
18	-0.308	0.553	-0.155	-0.4
19	-0.116	-0.273	0.269	0.039

Standard thresholds

P-value	Threshold
0.001	4.62756
0.0005	5.70196
0.0001	7.49891