ETV6.H14INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETV6.H14INVIVO.1.P.B
Gene (human)	ETV6 (GeneCards)
Gene synonyms (human)	TEL, TEL1
Gene (mouse)	Etv6
Gene synonyms (mouse)	Tel, Tel1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	dvvMGGAAGYRv
GC content	52.11%
Information content (bits; total / per base)	12.018 / 1.001
Data sources	ChIP-Seq
Aligned words	1000
Previous names	ETV6.H12INVIVO.1.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (35)	0.879	0.903	0.764	0.811	0.902	0.93	3.497	3.939	136.77	174.745
Mouse	4 (25)	0.74	0.847	0.618	0.737	0.774	0.848	2.477	2.928	46.585	193.602

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.763	0.73	0.635	0.633	0.564	0.578
Non-Methyl HT-SELEX, 2 experiments	best	0.822	0.789	0.672	0.671	0.582	0.6

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETV6-like {3.5.2.6} (TFClass)
TFClass ID	TFClass: 3.5.2.6.1
HGNC	HGNC:3495
MGI	MGI:109336
EntrezGene (human)	GeneID:2120 (SSTAR profile)
EntrezGene (mouse)	GeneID:14011 (SSTAR profile)
UniProt ID (human)	ETV6_HUMAN
UniProt ID (mouse)	ETV6_MOUSE
UniProt AC (human)	P41212 (TFClass)
UniProt AC (mouse)	P97360 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ETV6.H14INVIVO.1.P.B.pcm
PWM	ETV6.H14INVIVO.1.P.B.pwm
PFM	ETV6.H14INVIVO.1.P.B.pfm
Threshold to P-value map	ETV6.H14INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	ETV6.H14INVIVO.1.P.B_jaspar_format.txt
MEME format	ETV6.H14INVIVO.1.P.B_meme_format.meme
Transfac format	ETV6.H14INVIVO.1.P.B_transfac_format.txt
Homer format	ETV6.H14INVIVO.1.P.B_homer_format_0.001.txt ETV6.H14INVIVO.1.P.B_homer_format_0.0005.txt ETV6.H14INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	550.0	48.0	250.0	152.0
02	462.0	145.0	333.0	60.0
03	152.0	385.0	440.0	23.0
04	670.0	225.0	91.0	14.0
05	9.0	3.0	983.0	5.0
06	0.0	3.0	996.0	1.0
07	990.0	3.0	5.0	2.0
08	982.0	0.0	11.0	7.0
09	153.0	11.0	832.0	4.0
10	117.0	120.0	112.0	651.0
11	243.0	64.0	626.0	67.0
12	347.0	131.0	436.0	86.0

PFM

	A	C	G	T
01	0.55	0.048	0.25	0.152
02	0.462	0.145	0.333	0.06
03	0.152	0.385	0.44	0.023
04	0.67	0.225	0.091	0.014
05	0.009	0.003	0.983	0.005
06	0.0	0.003	0.996	0.001
07	0.99	0.003	0.005	0.002
08	0.982	0.0	0.011	0.007
09	0.153	0.011	0.832	0.004
10	0.117	0.12	0.112	0.651
11	0.243	0.064	0.626	0.067
12	0.347	0.131	0.436	0.086

PWM

	A	C	G	T
01	0.785	-1.622	0.0	-0.493
02	0.611	-0.54	0.285	-1.406
03	-0.493	0.429	0.562	-2.32
04	0.982	-0.105	-0.999	-2.773
05	-3.156	-3.975	1.364	-3.622
06	-4.982	-3.975	1.377	-4.525
07	1.371	-3.975	-3.622	-4.213
08	1.363	-4.982	-2.985	-3.362
09	-0.487	-2.985	1.198	-3.783
10	-0.752	-0.727	-0.795	0.953
11	-0.028	-1.343	0.914	-1.298
12	0.326	-0.64	0.553	-1.054

Standard thresholds

P-value	Threshold
0.001	3.999115
0.0005	5.15746
0.0001	7.39681