MotifERG.H14RSNP.1.SM.B
Gene (human)ERG
(GeneCards)
Gene synonyms (human)
Gene (mouse)Erg
Gene synonyms (mouse)Erg-3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnWCCGGAAGTvn
GC content56.34%
Information content (bits; total / per base)14.686 / 1.224
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2374
Previous namesERG.H12RSNP.1.SM.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 42 (221) 0.879 0.954 0.804 0.931 0.829 0.933 2.682 4.458 133.553 417.959
Mouse 11 (64) 0.924 0.972 0.843 0.937 0.889 0.96 3.356 4.447 239.886 465.347

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.988 0.981 0.887 0.895 0.705 0.744
best 0.999 0.998 0.995 0.992 0.989 0.984
Methyl HT-SELEX, 3 experiments median 0.803 0.761 0.65 0.651 0.568 0.587
best 0.817 0.776 0.679 0.67 0.589 0.602
Non-Methyl HT-SELEX, 7 experiments median 0.992 0.986 0.945 0.933 0.763 0.788
best 0.999 0.998 0.995 0.992 0.989 0.984

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.42 11.836 0.231 0.194

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.865 0.698 0.846 0.532
batch 2 0.905 0.784 0.864 0.597
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilyETS-like {3.5.2.1} (TFClass)
TFClass IDTFClass: 3.5.2.1.7
HGNCHGNC:3446
MGIMGI:95415
EntrezGene (human)GeneID:2078
(SSTAR profile)
EntrezGene (mouse)GeneID:13876
(SSTAR profile)
UniProt ID (human)ERG_HUMAN
UniProt ID (mouse)ERG_MOUSE
UniProt AC (human)P11308
(TFClass)
UniProt AC (mouse)P81270
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 42 human, 11 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01670.5609.5427.5666.5
021619.2516.25253.25485.25
0321.02250.0101.02.0
0483.02291.00.00.0
050.00.02374.00.0
060.00.02374.00.0
072374.00.00.00.0
082326.00.00.048.0
09591.02.01781.00.0
102.0580.050.01742.0
11698.25282.251187.25206.25
12543.0832.0638.0361.0
PFM
ACGT
010.2820.2570.180.281
020.6820.0070.1070.204
030.0090.9480.0430.001
040.0350.9650.00.0
050.00.01.00.0
060.00.01.00.0
071.00.00.00.0
080.980.00.00.02
090.2490.0010.750.0
100.0010.2440.0210.734
110.2940.1190.50.087
120.2290.350.2690.152
PWM
ACGT
010.1220.027-0.3270.116
021.002-3.488-0.847-0.201
03-3.2561.33-1.755-5.017
04-1.9471.348-5.725-5.725
05-5.725-5.7251.384-5.725
06-5.725-5.7251.384-5.725
071.384-5.725-5.725-5.725
081.363-5.725-5.725-2.478
09-0.004-5.0171.097-5.725
10-5.017-0.023-2.4391.075
110.162-0.740.692-1.051
12-0.0890.3370.072-0.495
Standard thresholds
P-value Threshold
0.001 1.527075
0.0005 3.06824
0.0001 6.349095