ERF.H14INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ERF.H14INVITRO.0.PS.A
Gene (human)	ERF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Erf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	ddnSGGAAGbn
GC content	56.55%
Information content (bits; total / per base)	9.879 / 0.898
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1638
Previous names	ERF.H12INVITRO.0.PS.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (25)	0.679	0.73	0.515	0.555	0.643	0.721	1.532	2.253	29.538	64.62
Mouse	7 (41)	0.701	0.77	0.552	0.625	0.686	0.73	1.737	2.239	25.125	52.301

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.608	0.581	0.548	0.545	0.521	0.526
Non-Methyl HT-SELEX, 2 experiments	best	0.619	0.591	0.554	0.551	0.524	0.529

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETS-like {3.5.2.1} (TFClass)
TFClass ID	TFClass: 3.5.2.1.11
HGNC	HGNC:3444
MGI	MGI:109637
EntrezGene (human)	GeneID:2077 (SSTAR profile)
EntrezGene (mouse)	GeneID:13875 (SSTAR profile)
UniProt ID (human)	ERF_HUMAN
UniProt ID (mouse)	ERF_MOUSE
UniProt AC (human)	P50548 (TFClass)
UniProt AC (mouse)	P70459 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 7 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ERF.H14INVITRO.0.PS.A.pcm
PWM	ERF.H14INVITRO.0.PS.A.pwm
PFM	ERF.H14INVITRO.0.PS.A.pfm
Threshold to P-value map	ERF.H14INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	ERF.H14INVITRO.0.PS.A_jaspar_format.txt
MEME format	ERF.H14INVITRO.0.PS.A_meme_format.meme
Transfac format	ERF.H14INVITRO.0.PS.A_transfac_format.txt
Homer format	ERF.H14INVITRO.0.PS.A_homer_format_0.001.txt ERF.H14INVITRO.0.PS.A_homer_format_0.0005.txt ERF.H14INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	371.75	268.75	662.75	334.75
02	589.5	92.5	495.5	460.5
03	331.0	505.0	486.0	316.0
04	177.0	941.0	504.0	16.0
05	0.0	0.0	1638.0	0.0
06	0.0	0.0	1638.0	0.0
07	1638.0	0.0	0.0	0.0
08	1449.0	0.0	2.0	187.0
09	469.0	17.0	1151.0	1.0
10	29.5	469.5	433.5	705.5
11	434.25	262.25	623.25	318.25

PFM

	A	C	G	T
01	0.227	0.164	0.405	0.204
02	0.36	0.056	0.303	0.281
03	0.202	0.308	0.297	0.193
04	0.108	0.574	0.308	0.01
05	0.0	0.0	1.0	0.0
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	0.885	0.0	0.001	0.114
09	0.286	0.01	0.703	0.001
10	0.018	0.287	0.265	0.431
11	0.265	0.16	0.38	0.194

PWM

	A	C	G	T
01	-0.096	-0.419	0.48	-0.201
02	0.363	-1.472	0.19	0.117
03	-0.212	0.209	0.171	-0.258
04	-0.833	0.829	0.207	-3.137
05	-5.404	-5.404	1.383	-5.404
06	-5.404	-5.404	1.383	-5.404
07	1.383	-5.404	-5.404	-5.404
08	1.26	-5.404	-4.671	-0.778
09	0.135	-3.083	1.031	-4.972
10	-2.574	0.136	0.057	0.542
11	0.058	-0.443	0.418	-0.251

Standard thresholds

P-value	Threshold
0.001	5.196115
0.0005	6.234145
0.0001	7.5803