| Motif | EPAS1.H14INVIVO.0.P.B |
| Gene (human) | EPAS1 (GeneCards) |
| Gene synonyms (human) | BHLHE73, HIF2A, MOP2, PASD2 |
| Gene (mouse) | Epas1 |
| Gene synonyms (mouse) | Hif2a |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | EPAS1.H14INVIVO.0.P.B |
| Gene (human) | EPAS1 (GeneCards) |
| Gene synonyms (human) | BHLHE73, HIF2A, MOP2, PASD2 |
| Gene (mouse) | Epas1 |
| Gene synonyms (mouse) | Hif2a |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | vKRCGTGhh |
| GC content | 58.73% |
| Information content (bits; total / per base) | 9.273 / 1.03 |
| Data sources | ChIP-Seq |
| Aligned words | 1000 |
| Previous names | EPAS1.H12INVIVO.0.P.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 14 (90) | 0.854 | 0.92 | 0.776 | 0.861 | 0.822 | 0.912 | 3.002 | 3.674 | 186.538 | 417.108 |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 28.417 | 8.124 | 0.45 | 0.357 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | PAS {1.2.5} (TFClass) |
| TF subfamily | PAS-AHR {1.2.5.1} (TFClass) |
| TFClass ID | TFClass: 1.2.5.1.7 |
| HGNC | HGNC:3374 |
| MGI | MGI:109169 |
| EntrezGene (human) | GeneID:2034 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:13819 (SSTAR profile) |
| UniProt ID (human) | EPAS1_HUMAN |
| UniProt ID (mouse) | EPAS1_MOUSE |
| UniProt AC (human) | Q99814 (TFClass) |
| UniProt AC (mouse) | P97481 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 14 human, 0 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | EPAS1.H14INVIVO.0.P.B.pcm |
| PWM | EPAS1.H14INVIVO.0.P.B.pwm |
| PFM | EPAS1.H14INVIVO.0.P.B.pfm |
| Threshold to P-value map | EPAS1.H14INVIVO.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | EPAS1.H14INVIVO.0.P.B_jaspar_format.txt |
| MEME format | EPAS1.H14INVIVO.0.P.B_meme_format.meme |
| Transfac format | EPAS1.H14INVIVO.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 210.0 | 259.0 | 454.0 | 77.0 |
| 02 | 136.0 | 47.0 | 261.0 | 556.0 |
| 03 | 757.0 | 58.0 | 142.0 | 43.0 |
| 04 | 7.0 | 955.0 | 2.0 | 36.0 |
| 05 | 11.0 | 6.0 | 971.0 | 12.0 |
| 06 | 1.0 | 0.0 | 1.0 | 998.0 |
| 07 | 0.0 | 1.0 | 990.0 | 9.0 |
| 08 | 339.0 | 457.0 | 78.0 | 126.0 |
| 09 | 194.0 | 436.0 | 168.0 | 202.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.21 | 0.259 | 0.454 | 0.077 |
| 02 | 0.136 | 0.047 | 0.261 | 0.556 |
| 03 | 0.757 | 0.058 | 0.142 | 0.043 |
| 04 | 0.007 | 0.955 | 0.002 | 0.036 |
| 05 | 0.011 | 0.006 | 0.971 | 0.012 |
| 06 | 0.001 | 0.0 | 0.001 | 0.998 |
| 07 | 0.0 | 0.001 | 0.99 | 0.009 |
| 08 | 0.339 | 0.457 | 0.078 | 0.126 |
| 09 | 0.194 | 0.436 | 0.168 | 0.202 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.173 | 0.035 | 0.594 | -1.162 |
| 02 | -0.603 | -1.642 | 0.043 | 0.796 |
| 03 | 1.103 | -1.439 | -0.56 | -1.728 |
| 04 | -3.362 | 1.335 | -4.213 | -1.898 |
| 05 | -2.985 | -3.484 | 1.352 | -2.909 |
| 06 | -4.525 | -4.982 | -4.525 | 1.379 |
| 07 | -4.982 | -4.525 | 1.371 | -3.156 |
| 08 | 0.303 | 0.6 | -1.15 | -0.678 |
| 09 | -0.252 | 0.553 | -0.394 | -0.212 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.09449 |
| 0.0005 | 5.99171 |
| 0.0001 | 7.445355 |