ELF5.H14RSNP.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF5.H14RSNP.1.S.B
Gene (human)	ELF5 (GeneCards)
Gene synonyms (human)	ESE2
Gene (mouse)	Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	vnAbSCGGAAGTdn
GC content	55.1%
Information content (bits; total / per base)	17.195 / 1.228
Data sources	HT-SELEX
Aligned words	5718
Previous names	ELF5.H12RSNP.1.S.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.795	0.797	0.74	0.743	0.862	0.882	3.402	3.501	217.481	223.319
Mouse	8 (45)	0.75	0.85	0.672	0.829	0.834	0.907	2.665	3.698	123.602	216.143

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 12 experiments	median	0.986	0.974	0.92	0.908	0.792	0.79
Overall, 12 experiments	best	0.999	0.999	0.997	0.996	0.946	0.928
Methyl HT-SELEX, 3 experiments	median	0.987	0.973	0.972	0.956	0.935	0.915
Methyl HT-SELEX, 3 experiments	best	0.988	0.975	0.976	0.963	0.946	0.928
Non-Methyl HT-SELEX, 9 experiments	median	0.985	0.976	0.905	0.886	0.771	0.79
Non-Methyl HT-SELEX, 9 experiments	best	0.999	0.999	0.997	0.996	0.936	0.928

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.791	0.379	0.754	0.437
batch 2	0.776	0.556	0.777	0.573

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.3
HGNC	HGNC:3320
MGI	MGI:1335079
EntrezGene (human)	GeneID:2001 (SSTAR profile)
EntrezGene (mouse)	GeneID:13711 (SSTAR profile)
UniProt ID (human)	ELF5_HUMAN
UniProt ID (mouse)	ELF5_MOUSE
UniProt AC (human)	Q9UKW6 (TFClass)
UniProt AC (mouse)	Q8VDK3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 8 mouse
HT-SELEX	9
Methyl-HT-SELEX	3
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ELF5.H14RSNP.1.S.B.pcm
PWM	ELF5.H14RSNP.1.S.B.pwm
PFM	ELF5.H14RSNP.1.S.B.pfm
Threshold to P-value map	ELF5.H14RSNP.1.S.B.thr
Motif in other formats
JASPAR format	ELF5.H14RSNP.1.S.B_jaspar_format.txt
MEME format	ELF5.H14RSNP.1.S.B_meme_format.meme
Transfac format	ELF5.H14RSNP.1.S.B_transfac_format.txt
Homer format	ELF5.H14RSNP.1.S.B_homer_format_0.001.txt ELF5.H14RSNP.1.S.B_homer_format_0.0005.txt ELF5.H14RSNP.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	992.75	1523.75	2340.75	860.75
02	2170.25	934.25	1229.25	1384.25
03	5397.0	6.0	13.0	302.0
04	489.0	3380.0	774.0	1075.0
05	132.0	3450.0	2135.0	1.0
06	338.0	5380.0	0.0	0.0
07	0.0	0.0	5718.0	0.0
08	0.0	0.0	5718.0	0.0
09	5718.0	0.0	0.0	0.0
10	5718.0	0.0	0.0	0.0
11	0.0	0.0	5718.0	0.0
12	0.0	3.0	0.0	5715.0
13	2730.0	375.0	1802.0	811.0
14	1243.0	1857.0	1753.0	865.0

PFM

	A	C	G	T
01	0.174	0.266	0.409	0.151
02	0.38	0.163	0.215	0.242
03	0.944	0.001	0.002	0.053
04	0.086	0.591	0.135	0.188
05	0.023	0.603	0.373	0.0
06	0.059	0.941	0.0	0.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	1.0	0.0
09	1.0	0.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.0	0.0	1.0	0.0
12	0.0	0.001	0.0	0.999
13	0.477	0.066	0.315	0.142
14	0.217	0.325	0.307	0.151

PWM

	A	C	G	T
01	-0.364	0.064	0.493	-0.506
02	0.417	-0.425	-0.151	-0.032
03	1.327	-5.167	-4.548	-1.549
04	-1.07	0.86	-0.612	-0.285
05	-2.368	0.88	0.401	-6.115
06	-1.437	1.324	-6.495	-6.495
07	-6.495	-6.495	1.385	-6.495
08	-6.495	-6.495	1.385	-6.495
09	1.385	-6.495	-6.495	-6.495
10	1.385	-6.495	-6.495	-6.495
11	-6.495	-6.495	1.385	-6.495
12	-6.495	-5.625	-6.495	1.385
13	0.646	-1.334	0.231	-0.566
14	-0.14	0.261	0.204	-0.501

Standard thresholds

P-value	Threshold
0.001	-2.76293
0.0005	-0.29918
0.0001	3.77731