ELF5.H14INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF5.H14INVIVO.1.S.B
Gene (human)	ELF5 (GeneCards)
Gene synonyms (human)	ESE2
Gene (mouse)	Elf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	vnAbSCGGAAGTRn
GC content	54.67%
Information content (bits; total / per base)	17.348 / 1.239
Data sources	HT-SELEX
Aligned words	5544
Previous names	ELF5.H12INVIVO.1.S.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.795	0.797	0.739	0.744	0.862	0.881	3.421	3.494	218.721	223.174
Mouse	8 (45)	0.75	0.85	0.673	0.83	0.839	0.91	2.711	3.802	129.959	228.538

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 12 experiments	median	0.985	0.975	0.919	0.906	0.791	0.789
Overall, 12 experiments	best	0.999	0.999	0.997	0.996	0.946	0.928
Methyl HT-SELEX, 3 experiments	median	0.988	0.974	0.971	0.956	0.934	0.915
Methyl HT-SELEX, 3 experiments	best	0.989	0.977	0.977	0.964	0.946	0.928
Non-Methyl HT-SELEX, 9 experiments	median	0.984	0.976	0.903	0.884	0.771	0.788
Non-Methyl HT-SELEX, 9 experiments	best	0.999	0.999	0.997	0.996	0.934	0.927

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.797	0.375	0.748	0.433
batch 2	0.78	0.562	0.774	0.57

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	EHF-like {3.5.2.4} (TFClass)
TFClass ID	TFClass: 3.5.2.4.3
HGNC	HGNC:3320
MGI	MGI:1335079
EntrezGene (human)	GeneID:2001 (SSTAR profile)
EntrezGene (mouse)	GeneID:13711 (SSTAR profile)
UniProt ID (human)	ELF5_HUMAN
UniProt ID (mouse)	ELF5_MOUSE
UniProt AC (human)	Q9UKW6 (TFClass)
UniProt AC (mouse)	Q8VDK3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 8 mouse
HT-SELEX	9
Methyl-HT-SELEX	3
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ELF5.H14INVIVO.1.S.B.pcm
PWM	ELF5.H14INVIVO.1.S.B.pwm
PFM	ELF5.H14INVIVO.1.S.B.pfm
Threshold to P-value map	ELF5.H14INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	ELF5.H14INVIVO.1.S.B_jaspar_format.txt
MEME format	ELF5.H14INVIVO.1.S.B_meme_format.meme
Transfac format	ELF5.H14INVIVO.1.S.B_transfac_format.txt
Homer format	ELF5.H14INVIVO.1.S.B_homer_format_0.001.txt ELF5.H14INVIVO.1.S.B_homer_format_0.0005.txt ELF5.H14INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	895.25	1332.25	2571.25	745.25
02	2116.0	878.0	1189.0	1361.0
03	5263.0	1.0	6.0	274.0
04	544.0	3067.0	681.0	1252.0
05	125.0	3229.0	2188.0	2.0
06	409.0	5135.0	0.0	0.0
07	0.0	0.0	5544.0	0.0
08	0.0	0.0	5544.0	0.0
09	5544.0	0.0	0.0	0.0
10	5544.0	0.0	0.0	0.0
11	0.0	0.0	5544.0	0.0
12	0.0	1.0	0.0	5543.0
13	3013.0	193.0	1702.0	636.0
14	990.0	1947.0	1683.0	924.0

PFM

	A	C	G	T
01	0.161	0.24	0.464	0.134
02	0.382	0.158	0.214	0.245
03	0.949	0.0	0.001	0.049
04	0.098	0.553	0.123	0.226
05	0.023	0.582	0.395	0.0
06	0.074	0.926	0.0	0.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	1.0	0.0
09	1.0	0.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.0	0.0	1.0	0.0
12	0.0	0.0	0.0	1.0
13	0.543	0.035	0.307	0.115
14	0.179	0.351	0.304	0.167

PWM

	A	C	G	T
01	-0.436	-0.039	0.617	-0.619
02	0.423	-0.456	-0.153	-0.018
03	1.333	-6.087	-5.137	-1.615
04	-0.933	0.793	-0.709	-0.102
05	-2.39	0.845	0.456	-5.811
06	-1.217	1.309	-6.468	-6.468
07	-6.468	-6.468	1.385	-6.468
08	-6.468	-6.468	1.385	-6.468
09	1.385	-6.468	-6.468	-6.468
10	1.385	-6.468	-6.468	-6.468
11	-6.468	-6.468	1.385	-6.468
12	-6.468	-6.087	-6.468	1.385
13	0.776	-1.962	0.205	-0.777
14	-0.336	0.339	0.194	-0.405

Standard thresholds

P-value	Threshold
0.001	-2.98014
0.0005	-0.48729
0.0001	3.645215