ELF4.H14RSNP.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF4.H14RSNP.0.PS.A
Gene (human)	ELF4 (GeneCards)
Gene synonyms (human)	ELFR, MEF
Gene (mouse)	Elf4
Gene synonyms (mouse)	Mef
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	dvSCGGAAGYR
GC content	60.64%
Information content (bits; total / per base)	13.331 / 1.212
Data sources	ChIP-Seq + HT-SELEX
Aligned words	997
Previous names	ELF4.H12RSNP.0.PS.A

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.768	0.882	0.703	0.836	0.745	0.876	2.673	3.755	70.244	172.509
Mouse	3 (19)	0.969	0.979	0.925	0.954	0.961	0.972	4.491	4.688	242.432	369.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.994	0.995	0.991	0.988	0.982
Overall, 4 experiments	best	0.998	0.997	0.998	0.996	0.995	0.993
Methyl HT-SELEX, 2 experiments	median	0.996	0.993	0.994	0.99	0.985	0.978
Methyl HT-SELEX, 2 experiments	best	0.997	0.994	0.995	0.992	0.99	0.985
Non-Methyl HT-SELEX, 2 experiments	median	0.997	0.995	0.996	0.993	0.99	0.986
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.998	0.996	0.995	0.993

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.914	0.762	0.908	0.709

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELF1-like {3.5.2.3} (TFClass)
TFClass ID	TFClass: 3.5.2.3.3
HGNC	HGNC:3319
MGI	MGI:1928377
EntrezGene (human)	GeneID:2000 (SSTAR profile)
EntrezGene (mouse)	GeneID:56501 (SSTAR profile)
UniProt ID (human)	ELF4_HUMAN
UniProt ID (mouse)	ELF4_MOUSE
UniProt AC (human)	Q99607 (TFClass)
UniProt AC (mouse)	Q9Z2U4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ELF4.H14RSNP.0.PS.A.pcm
PWM	ELF4.H14RSNP.0.PS.A.pwm
PFM	ELF4.H14RSNP.0.PS.A.pfm
Threshold to P-value map	ELF4.H14RSNP.0.PS.A.thr
Motif in other formats
JASPAR format	ELF4.H14RSNP.0.PS.A_jaspar_format.txt
MEME format	ELF4.H14RSNP.0.PS.A_meme_format.meme
Transfac format	ELF4.H14RSNP.0.PS.A_transfac_format.txt
Homer format	ELF4.H14RSNP.0.PS.A_homer_format_0.001.txt ELF4.H14RSNP.0.PS.A_homer_format_0.0005.txt ELF4.H14RSNP.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	581.0	96.0	114.0	206.0
02	191.0	488.0	214.0	104.0
03	54.0	765.0	170.0	8.0
04	151.0	841.0	4.0	1.0
05	2.0	0.0	995.0	0.0
06	0.0	2.0	995.0	0.0
07	996.0	0.0	1.0	0.0
08	993.0	0.0	1.0	3.0
09	50.0	40.0	905.0	2.0
10	95.0	229.0	34.0	639.0
11	158.0	157.0	599.0	83.0

PFM

	A	C	G	T
01	0.583	0.096	0.114	0.207
02	0.192	0.489	0.215	0.104
03	0.054	0.767	0.171	0.008
04	0.151	0.844	0.004	0.001
05	0.002	0.0	0.998	0.0
06	0.0	0.002	0.998	0.0
07	0.999	0.0	0.001	0.0
08	0.996	0.0	0.001	0.003
09	0.05	0.04	0.908	0.002
10	0.095	0.23	0.034	0.641
11	0.158	0.157	0.601	0.083

PWM

	A	C	G	T
01	0.842	-0.943	-0.774	-0.189
02	-0.264	0.668	-0.151	-0.865
03	-1.505	1.117	-0.379	-3.251
04	-0.497	1.211	-3.78	-4.522
05	-4.21	-4.979	1.379	-4.979
06	-4.979	-4.21	1.379	-4.979
07	1.38	-4.979	-4.522	-4.979
08	1.377	-4.979	-4.522	-3.972
09	-1.579	-1.794	1.284	-4.21
10	-0.953	-0.084	-1.949	0.937
11	-0.452	-0.458	0.873	-1.086

Standard thresholds

P-value	Threshold
0.001	3.17172
0.0005	4.47641
0.0001	7.180585